In this issue (8 articles)

1. Perspective

   Innate immune responses to DNA viruses

   Ying Nie, Yan-Yi Wang Pages 1-7

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2. Review

   Recognition of self and altered self by T cells in autoimmunity and allergy

   Lei Yin, Shaodong Dai, Gina Clayton, Wei Gao, Yang Wang, John Kappler… Pages 8-16

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3. Review

   Immune plexins and semaphorins: old proteins, new immune functions

   Kelly Roney, Eda Holl, Jenny Ting Pages 17-26

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4. Review

   The essential adaptors of innate immune signaling

   Huihui Chen, Zhengfan Jiang Pages 27-39

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5. Review

   Regulation of TLR7/9 signaling in plasmacytoid dendritic cells

   Musheng Bao, Yong-Jun Liu Pages 40-52

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6. 

   Communication

   Caenorhabditis elegans mom-4 is required for the activation of the p38 MAPK signaling pathway in the response to Pseudomonas aeruginosa infection

   Ajing Xu, Guojun Shi, Feng Liu, Baoxue Ge Pages 53-61

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7. 

   Communication

   USP2a positively regulates TCR-induced NF-κB activation by bridging MALT1-TRAF6

   Yi Li, Xiao He, Shuai Wang, Hong-Bing Shu, Yu Liu Pages 62-70

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8. 

   Research Article

   Combined effects of p53 and MDM2 polymorphisms on susceptibility and surgical prognosis in hepatitis B virus-related hepatocellular carcinoma

   Yun Yang, Tian Xia, Ning Li, Jin Zhang, Yuan Yang, Wenming Cong… Pages 71-81

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