In this issue (31 articles)

1. Then and Now

   Estimating insulin sensitivity and beta cell function: perspectives from the modern pandemics of obesity and type 2 diabetes

   J. J. Nolan, K. Færch Pages 2863-2867

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2. Review

   Does the gut microbiota have a role in type 1 diabetes? Early evidence from humans and animal models of the disease

   M. A. Atkinson, A. Chervonsky Pages 2868-2877

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3. Systematic Review

   Variation between countries in the frequency of diabetic ketoacidosis at first presentation of type 1 diabetes in children: a systematic review

   J. A. Usher-Smith, M. Thompson, A. Ercole, F. M. Walter Pages 2878-2894

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4. Meta-analysis

   Sedentary time in adults and the association with diabetes, cardiovascular disease and death: systematic review and meta-analysis

   E. G. Wilmot, C. L. Edwardson, F. A. Achana, M. J. Davies, T. Gorely… Pages 2895-2905

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5. 

   Meta-analysis

   The association of ulceration of the foot with cardiovascular and all-cause mortality in patients with diabetes: a meta-analysis

   J. R. W. Brownrigg, J. Davey, P. J. Holt, W. A. Davis, M. M. Thompson… Pages 2906-2912

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6. Article

   Urinary podocalyxin is an early marker for podocyte injury in patients with diabetes: establishment of a highly sensitive ELISA to detect urinary podocalyxin

   M. Hara, K. Yamagata, Y. Tomino, A. Saito, Y. Hirayama, S. Ogasawara… Pages 2913-2919

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7. Article

   N-Acetylcysteine inhibits platelet–monocyte conjugation in patients with type 2 diabetes with depleted intraplatelet glutathione: a randomised controlled trial

   A. T. Treweeke, T. J. Winterburn, I. Mackenzie, F. Barrett, C. Barr… Pages 2920-2928

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8. Article

   Hospitalised hip fracture risk with rosiglitazone and pioglitazone use compared with other glucose-lowering drugs

   H. M. Colhoun, S. J. Livingstone, H. C. Looker, A. D. Morris, S. H. Wild… Pages 2929-2937

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9. 

   Article

   Area-based socioeconomic status, type 2 diabetes and cardiovascular mortality in Scotland

   C. A. Jackson, N. R. V. Jones, J. J. Walker, C. M. Fischbacher… Pages 2938-2945

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10. 

    Article

    The relationship between glycaemic control and heart failure in 83,021 patients with type 2 diabetes

    M. Lind, M. Olsson, A. Rosengren, A.-M. Svensson, I. Bounias… Pages 2946-2953

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11. 

    Article

    Erythrocyte trans-fatty acids, type 2 diabetes and cardiovascular risk factors in middle-aged and older Chinese individuals

    D. X. Yu, Q. Sun, X. W. Ye, A. Pan, G. Zong, Y. H. Zhou, H. X. Li, F. B. Hu… Pages 2954-2962

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12. 

    Article

    HLA class II is a factor in cardiovascular morbidity and mortality rates in patients with type 1 diabetes

    J. Söderlund, C. Forsblom, J. Ilonen, L. M. Thorn, J. Wadén, M. Parkkonen… Pages 2963-2969

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13. 

    Article

    Transferability and fine-mapping of glucose and insulin quantitative trait loci across populations: CARe, the Candidate Gene Association Resource

    C. -T. Liu, M. C. Y. Ng, D. Rybin, A. Adeyemo, S. J. Bielinski… Pages 2970-2984

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14. Short Communication

    Beta cell nuclear musculoaponeurotic fibrosarcoma oncogene family A (MafA) is deficient in type 2 diabetes

    A. E. Butler, R. P. Robertson, R. Hernandez, A. V. Matveyenko, T. Gurlo… Pages 2985-2988

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15. 

    Article

    Degradation of islet amyloid polypeptide by neprilysin

    H. Guan, K. M. Chow, R. Shah, C. J. Rhodes, L. B. Hersh Pages 2989-2998

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16. 

    Article

    Cross-talk between the unfolded protein response and nuclear factor-κB signalling pathways regulates cytokine-mediated beta cell death in MIN6 cells and isolated mouse islets

    J. Y. Chan, T. J. Biden, D. R. Laybutt Pages 2999-3009

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17. 

    Article

    Interleukin-15 plays an essential role in the pathogenesis of autoimmune diabetes in the NOD mouse

    D. Bobbala, X.-L. Chen, C. Leblanc, M. Mayhue, J. Stankova, T. Tanaka… Pages 3010-3020

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18. Article

    Elevated NEFA levels impair glucose effectiveness by increasing net hepatic glycogenolysis

    S. Kehlenbrink, S. Koppaka, M. Martin, R. Relwani, M.-H. Cui, J.-H. Hwang… Pages 3021-3028

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19. 

    Article

    Marked resistance of femoral adipose tissue blood flow and lipolysis to adrenaline in vivo

    K. N. Manolopoulos, F. Karpe, K. N. Frayn Pages 3029-3037

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20. 

    Article

    The ghrelin O-acyltransferase–ghrelin system reduces TNF-α-induced apoptosis and autophagy in human visceral adipocytes

    A. Rodríguez, J. Gómez-Ambrosi, V. Catalán, F. Rotellar, V. Valentí… Pages 3038-3050

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