Pharmacodynamic Modeling of Sequence-Dependent Antitumor Activity of Insulin-like Growth Factor Blockade and Gemcitabine Amit KhatriRichard C. BrundageMark N. Kirstein Research Article 19 November 2011 Pages: 1 - 9
Absorption Enhancers: Applications and Advances Bruce J. Aungst Review Article 22 November 2011 Pages: 10 - 18
Common Deficiencies with Bioequivalence Submissions in Abbreviated New Drug Applications Assessed by FDA Qing LiuBarbara M. DavitDale P. Conner Regulatory Note 01 December 2011 Pages: 19 - 22
Comparison of Intestinal Absorption and Disposition of Structurally Similar Bioactive Flavones in Radix Scutellariae Chenrui LiLi ZhangZhong Zuo Research Article 14 December 2011 Pages: 23 - 34
PEGylation of a Factor VIII–Phosphatidylinositol Complex: Pharmacokinetics and Immunogenicity in Hemophilia A Mice Aaron PengMatthew P. KosloskiSathy V. Balu-Iyer Research Article 16 December 2011 Pages: 35 - 42
Synthesis and Pharmacological Characterization of a Novel Sigma Receptor Ligand with Improved Metabolic Stability and Antagonistic Effects Against Methamphetamine Michael J. SeminerioMatthew J. RobsonRae R. Matsumoto Research Article 20 December 2011 Pages: 43 - 51
The Risk of Recurrence in Breast Cancer Patients Treated with Tamoxifen: Polymorphisms of CYP2D6 and ABCB1 L. K. TehN. I. MohamedJ. Din Research Article 20 December 2011 Pages: 52 - 59
On Average: Data Exploration Based on Means Can Be Misleading Adrian DunneMila EtropolskiPartha Nandy Commentary 22 December 2011 Pages: 60 - 67
Effect of Cyclosporine and Rifampin on the Pharmacokinetics of Macitentan, a Tissue-Targeting Dual Endothelin Receptor Antagonist Shirin BrudererPäivi ÄänismaaJasper Dingemanse Research Article Open access 22 December 2011 Pages: 68 - 78
Modification of Disodium Cromoglycate Passage Across Lung Epithelium In Vitro Via Incorporation into Polymeric Microparticles Mehra HaghiRania SalamaPaul M. Young Research Article 28 December 2011 Pages: 79 - 86
Alteration in P-glycoprotein Functionality Affects Intrabrain Distribution of Quinidine More Than Brain Entry—A Study in Rats Subjected to Status Epilepticus by Kainate Stina SyvänenMaarten SchenkeElizabeth C. de Lange Research Article Open access 04 January 2012 Pages: 87 - 96
Disposition of Human Recombinant Lubricin in Naive Rats and in a Rat Model of Post-traumatic Arthritis After Intra-articular or Intravenous Administration Yulia VugmeysterQin WangMoisés A. Rivera-Bermúdez Research Article 07 January 2012 Pages: 97 - 104
Ligand-Binding Assays in the 21st Century Laboratory: Recommendations for an Automated Data Interchange Process Sheldon S. LeungJoel UsanskyDavid Rusnak Commentary 14 January 2012 Pages: 105 - 112
Ligand Binding Assays in the 21st Century Laboratory: Platforms Franklin P. SpriggsZhandong Don ZhongChad Ray Commentary 19 January 2012 Pages: 113 - 118
Covariate Pharmacokinetic Model Building in Oncology and its Potential Clinical Relevance Markus Joerger Review Article 25 January 2012 Pages: 119 - 132
Structure-Based Virtual Screening for Drug Discovery: a Problem-Centric Review Tiejun ChengQingliang LiStephen H. Bryant Review Article Open access 27 January 2012 Pages: 133 - 141
Ligand Binding Assays in the 21st Century Laboratory: Automation Ago B. AheneChris MorrowJohn Derent Commentary 01 February 2012 Pages: 142 - 153