Volume 8, Issue 1, March 2013

ISSN: 1872-5120 (Print) 1939-8042 (Online)

In this issue (5 articles)

  1. No Access

    Research Article

    Latent Variables-Based Process Modeling of a Continuous Hydrogenation Reaction in API Synthesis of Small Molecules

    Zhenqi Shi, Nikolay Zaborenko, David E. Reed Pages 1-10
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  2. No Access

    Research Article

    Computer-Aided Flowsheet Simulation of a Pharmaceutical Tablet Manufacturing Process Incorporating Wet Granulation

    Fani Boukouvala, Anwesha Chaudhury, Maitraye Sen… Pages 11-27
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  3. No Access

    Research Article

    Quality by Design Studies on Multi-response Pharmaceutical Formulation Modeling and Optimization

    Zhe Li, Byung Rae Cho, Brian J. Melloy Pages 28-44
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    Research Article

    Online Monitoring of Pharmaceutical Materials Using Multiple NIR Sensors—Part II: Blend End-point Determination

    Benoît Igne, Sameer Talwar, James K. Drennen III… Pages 45-55
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    Case Report

    Best Practices for Drug Substance Stress and Stability Studies During Early-Stage Development Part II—Conducting Abbreviated Long-Term and Accelerated Stability Testing on the First Clinical Drug Substance Batch to Confirm and Adjust the Drug Substance Retest Period/Powder for Oral Solution Shelf Life

    Q. Chan Li, K. Cohen, T. Tougas, F. Qiu, J. Li… Pages 56-65
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