1. Parkin’s substrates and the pathways leading to neuronal damage

   • Mark R. Cookson

   Review Article Pages: 1 - 13

2. Neuronal overexpression of COX-2 results in dominant production of PGE₂ and altered fever response

   • Svetlana Vidensky
   • Yan Zhang
   • Katrin Andreasson

   Original Research Pages: 15 - 27

3. Autoantibodies to amyloid β-peptide (Aβ) are increased in Alzheimer’s disease patients and Aβ antibodies can enhance Aβ neurotoxicity

   • Avindra Nath
   • Elizabeth Hall
   • Mark P. Mattson

   Original Research Pages: 29 - 39

4. NF2 Tumor suppressor gene

   • Irene Szijan
   • Daniel Rochefort
   • Guy A. Rouleau

   Original Research Pages: 41 - 52

5. Presenilin-1 mutation sensitizes oligodendrocytes to glutamate and amyloid toxicities, and exacerbates white matter damage and memory impairment in mice

   • Kirk Pak
   • Sic L. Chan
   • Mark P. Mattson

   Original Research Pages: 53 - 64