This journal presents a forum for the publication of papers in the rapidly growing area of Purinergic Signalling (through purines and pyrimidines), with its exceptionally wide spectrum of signalling functions in health and disease. Coverage includes original articles, reviews, hot topics and controversies, and meeting reports.
There is both short-term purinergic signalling in transmission and secretion and long-term (trophic) signalling in controlling cell proliferation, differentiation, motility and death in development and regeneration and there is increasing interest in the roles of purines and pyrimidines in pathophysiological conditions and their therapeutic potential in disease. At the molecular level, rapid progress has been made in understanding the mechanisms of nucleotide and nucleoside release, their extracellular metabolism, the intracellular signalling cascades elicited by receptor activation and the cross-talk with other essential signalling pathways.
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10 Volumes 41 Issues 481 Articles available from 2005 - 2014Browse Volumes & Issues
- Journal Title
- Purinergic Signalling
- Volume 1 / 2005 - Volume 10 / 2014
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- Springer Netherlands
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