Volume 30, Issue 4, April 2013

ISSN: 0724-8741 (Print) 1573-904X (Online)

In this issue (24 articles)

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  1. No Access

    Expert Review

    Delivery Systems and Local Administration Routes for Therapeutic siRNA

    Fabiana Testa Moura de Carvalho Vicentini… Pages 915-931
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  2. No Access

    Research Paper

    Pharmacokinetics and Metabolism of 2-Aminothiazoles with Antiprion Activity in Mice

    B. Michael Silber, Satish Rao, Kimberly L. Fife… Pages 932-950
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    Research Paper

    Measurement of Drug Concentration in the Stomach After Intragastric Administration of Drug Solution to Healthy Volunteers: Analysis of Intragastric Fluid Dynamics and Drug Absorption

    Shinji Yamashita, Makoto Kataoka, Haruki Higashino… Pages 951-958
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    Research Paper

    Oral Delivery of Ionic Complex of Ceftriaxone with Bile Acid Derivative in Non-human Primates

    Ok-Cheol Jeon, Seung Rim Hwang, Taslim A. Al-Hilal, Jin Woo Park… Pages 959-967
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    Research Paper

    Effect of pH and Excipients on Structure, Dynamics, and Long-Term Stability of a Model IgG1 Monoclonal Antibody upon Freeze-Drying

    Jihea Park, Karthik Nagapudi, Camille Vergara… Pages 968-984
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    Research Paper

    Accelerated Blood Clearance of PEGylated PLGA Nanoparticles Following Repeated Injections: Effects of Polymer Dose, PEG Coating, and Encapsulated Anticancer Drug

    Roonak Saadati, Simin Dadashzadeh, Zahra Abbasian… Pages 985-995
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    Research Paper

    Human Intestinal Transporter Database: QSAR Modeling and Virtual Profiling of Drug Uptake, Efflux and Interactions

    Alexander Sedykh, Denis Fourches, Jianmin Duan, Oliver Hucke… Pages 996-1007
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    Research Paper

    MicroRNA-302 Replacement Therapy Sensitizes Breast Cancer Cells to Ionizing Radiation

    Zhongxing Liang, Jeffrey Ahn, Donna Guo, John R. Votaw… Pages 1008-1016
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    Research Paper

    Relevance of PepT1 in the Intestinal Permeability and Oral Absorption of Cefadroxil

    Maria M. Posada, David E. Smith Pages 1017-1025
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    Research Paper

    Erythropoietin-Induced Erythroid Precursor Pool Depletion Causes Erythropoietin Hyporesponsiveness

    Xiaoyu Yan, Sihem Ait-Oudhia, Wojciech Krzyzanski Pages 1026-1036
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    Research Paper

    Investigation of Follicular and Non-follicular Pathways for Polyarginine and Oleic Acid-Modified Nanoparticles

    Pinaki R. Desai, Punit P. Shah, Patrick Hayden, Mandip Singh Pages 1037-1049
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    Research Paper

    Role of Drug Efflux and Uptake Transporters in Atazanavir Intestinal Permeability and Drug-Drug Interactions

    Olena Kis, Jason A. Zastre, Md. Tozammel Hoque… Pages 1050-1064
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    Research Paper

    Critical Solvent Properties Affecting the Particle Formation Process and Characteristics of Celecoxib-Loaded PLGA Microparticles via Spray-Drying

    Feng Wan, Adam Bohr, Morten Jonas Maltesen, Simon Bjerregaard… Pages 1065-1076
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    Research Paper

    The Implantable and Biodegradable PHBHHx 3D Scaffolds Loaded with Protein-Phospholipid Complex for Sustained Delivery of Proteins

    Qiang Peng, Yong-Jie Yang, Ting Zhang, Cheng-Yu Wu, Qin Yang… Pages 1077-1085
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    Research Paper

    In Vitro Investigations of the Efficacy of Cyclodextrin-siRNA Complexes Modified with Lipid-PEG-Octaarginine: Towards a Formulation Strategy for Non-viral Neuronal siRNA Delivery

    Aoife M. O’Mahony, Stephane Desgranges, Julien Ogier… Pages 1086-1098
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    Research Paper

    Transdermal Delivery of Molecules is Limited by Full Epidermis, Not Just Stratum Corneum

    Samantha N. Andrews, Eunhye Jeong, Mark R. Prausnitz Pages 1099-1109
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    Research Paper

    Joint Population Pharmacokinetic/Pharmacodynamic Model for the Heart Rate Effects at Rest and at the End of Exercise for Cilobradine

    Nieves Vélez de Mendizábal, Alexander Staab, Hans Günter Schäfer… Pages 1110-1122
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    Research Paper

    Moisture Uptake of Polyoxyethylene Glycol Glycerides Used as Matrices for Drug Delivery: Kinetic Modelling and Practical Implications

    Sheng Qi, Peter Belton, William McAuley, Doroty Codoni… Pages 1123-1136
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    Research Paper

    Nano-encapsulation of Vitamin D3 Active Metabolites for Application in Chemotherapy: Formulation Study and in Vitro Evaluation

    Eyad Almouazen, Sandrine Bourgeois, Lars Petter Jordheim… Pages 1137-1146
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    Research Paper

    Location-Dependent Coronary Artery Diffusive and Convective Mass Transport Properties of a Lipophilic Drug Surrogate Measured Using Nonlinear Microscopy

    Joseph T. Keyes, Bruce R. Simon, Jonathan P. Vande Geest Pages 1147-1160
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