Volume 30, Issue 3, March 2013

ISSN: 0724-8741 (Print) 1573-904X (Online)

In this issue (27 articles)

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  1. No Access

    Perspective

    Celiac Disease: A Challenging Disease for Pharmaceutical Scientists

    Simon Matoori, Gregor Fuhrmann, Jean-Christophe Leroux Pages 619-626
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    Research Paper

    Evaluation of Poly (1, 6-bis-(p-carboxyphenoxy) Hexane-co-sebacic Acid Microspheres for Controlled Basal Insulin Delivery

    Chandrasekar Manoharan, Jagdish Singh Pages 627-640
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    Research Paper

    Aggregation Mechanism of an IgG2 and two IgG1 Monoclonal Antibodies at low pH: From Oligomers to Larger Aggregates

    Paolo Arosio, Simonetta Rima, Massimo Morbidelli Pages 641-654
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    Research Paper

    Pharmacokinetic and Pharmacodynamic Modeling of Romiplostim in Animals

    Wojciech Krzyzanski, Liviawati Sutjandra, Juan Jose Perez-Ruixo… Pages 655-669
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    Research Paper

    Protected Graft Copolymer Excipient Leads to a Higher Acute Maximum Tolerated Dose and Extends Residence Time of Vasoactive Intestinal Peptide Significantly Better than Sterically Stabilized Micelles

    Sandra Reichstetter, Gerardo M. Castillo, Israel Rubinstein… Pages 670-682
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    Research Paper

    Exploration of Optimal Dosing Regimens of Haloperidol, a D2 Antagonist, via Modeling and Simulation Analysis in a D2 Receptor Occupancy Study

    Hyeong-Seok Lim, Su Jin Kim, Yook-Hwan Noh, Byung Chul Lee… Pages 683-693
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    Research Paper

    Lamellar Liquid Crystalline Phases for Cutaneous Delivery of Paclitaxel: Impact of the Monoglyceride

    Jaclyn M. Hosmer, Alexandre A. Steiner, Luciana B. Lopes Pages 694-706
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    Research Paper

    Interactions of Everolimus and Sorafenib in Whole Blood Lymphocyte Proliferation

    Dipti K. Pawaskar, Robert M. Straubinger, Gerald J. Fetterly… Pages 707-713
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    Research Paper

    Molecular Mobility as a Predictor of the Water Sorption by Annealed Amorphous Trehalose

    Sunny P. Bhardwaj, Raj Suryanarayanan Pages 714-720
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    Research Paper

    Efficacy of Mucoadhesive Hydrogel Microparticles of Whey Protein and Alginate for Oral Insulin Delivery

    Emmanuelle Déat-Lainé, Valérie Hoffart, Ghislain Garrait… Pages 721-734
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    Research Paper

    Liquid Formulations for Stabilizing IgMs During Physical Stress and Long-Term Storage

    Monika Mueller, Maybelle Q. T. Loh, Rupert Tscheliessnig… Pages 735-750
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    Research Paper

    Interspecies Modeling and Prediction of Human Exenatide Pharmacokinetics

    Ting Chen, Donald E. Mager, Leonid Kagan Pages 751-760
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    Research Paper

    Cyclosporine Inhibition of Hepatic and Intestinal CYP3A4, Uptake and Efflux Transporters: Application of PBPK Modeling in the Assessment of Drug-Drug Interaction Potential

    Michael Gertz, Catherine M. Cartwright, Michael J. Hobbs… Pages 761-780
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    Research Paper

    Drug Delivery Characteristics of the Progenitor Bronchial Epithelial Cell Line VA10

    Berglind Eva Benediktsdóttir, Ari Jón Arason… Pages 781-791
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    Research Paper

    Skin Permeation of Small-Molecule Drugs, Macromolecules, and Nanoparticles Mediated by a Fractional Carbon Dioxide Laser: The Role of Hair Follicles

    Woan-Ruoh Lee, Shing-Chuan Shen, Saleh A. Al-Suwayeh… Pages 792-802
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    Research Paper

    The Impact of Glycosylation on the Pharmacokinetics of a TNFR2:Fc Fusion Protein Expressed in Glycoengineered Pichia Pastoris

    Liming Liu, Sujatha Gomathinayagam, Lora Hamuro… Pages 803-812
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    Research Paper

    Respirable Low-Density Microparticles Formed In Situ from Aerosolized Brittle Matrices

    Alan B. Watts, Yi-Bo Wang, Keith P. Johnston… Pages 813-825
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    Research Paper

    Rapid Insight into Heating-Induced Phase Transformations in the Solid State of the Calcium Salt of Atorvastatin Using Multivariate Data Analysis

    Niels Peter Aae Christensen, Bernard Van Eerdenbrugh, Kaho Kwok… Pages 826-835
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    Research Paper

    Bioactivity and Bioavailability of Ginsenosides are Dependent on the Glycosidase Activities of the A/J Mouse Intestinal Microbiome Defined by Pyrosequencing

    Tao Niu, Diane L. Smith, Zhen Yang, Song Gao, Taijun Yin… Pages 836-846
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    Research Paper

    Involvement of a Novel Organic Cation Transporter in Verapamil Transport Across the Inner Blood-Retinal Barrier

    Yoshiyuki Kubo, Yusuke Kusagawa, Masanori Tachikawa… Pages 847-856
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