Volume 40, Issue 1, February 2013

ISSN: 1567-567X (Print) 1573-8744 (Online)

From Volume 1 (1973) to Volume 27 (1999), this journal was published as Journal of Pharmacokinetics and Biopharmaceutics.

In this issue (10 articles)

  1. No Access

    Original Paper

    Identification of the primary mechanism of action of an insulin secretagogue from meal test data in healthy volunteers based on an integrated glucose-insulin model

    Steve Choy, Emilie Hénin… Pages 1-10
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  2. No Access

    Original Paper

    Fractal structure of the liver: effect on drug elimination

    Michael Weiss Pages 11-14
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  3. No Access

    Original Paper

    Variability and singularity arising from poor compliance in a pharmacokinetic model I: the multi-IV case

    Pierre-Emmanuel Lévy Véhel… Pages 15-39
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  4. No Access

    Original Paper

    Compliance spectrum as a drug fingerprint of drug intake and drug disposition

    Olivier Barrière, Jun Li, Fahima Nekka Pages 41-52
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  5. No Access

    Original Paper

    Dose selection using a semi-mechanistic integrated glucose-insulin-glucagon model: designing phase 2 trials for a novel oral glucokinase activator

    Xin Zhang, Karen Schneck… Pages 53-65
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  6. No Access

    Original Paper

    Assessment of glycemic response to an oral glucokinase activator in a proof of concept study: application of a semi-mechanistic, integrated glucose-insulin-glucagon model

    Karen B. Schneck, Xin Zhang, Robert Bauer… Pages 67-80
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  7. No Access

    Original Paper

    Latent variable indirect response modeling of categorical endpoints representing change from baseline

    Chuanpu Hu, Zhenhua Xu, Alan M. Mendelsohn… Pages 81-91
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  8. No Access

    Original Paper

    The design and analysis of parallel experiments to produce structurally identifiable models

    S. Y. Amy Cheung, James W. T. Yates… Pages 93-100
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    Original Paper

    The effects of active metabolites on parameter estimation in linear mixed effect models of concentration–QT analyses

    Peter L. Bonate Pages 101-115
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  10. No Access

    Original Paper

    Population pharmacokinetic modeling and deconvolution of enantioselective absorption of eflornithine in the rat

    Carl-Christer Johansson, Peter Gennemark… Pages 117-128
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