Volume 39, Issue 6, December 2012

ISSN: 1567-567X (Print) 1573-8744 (Online)

From Volume 1 (1973) to Volume 27 (1999), this journal was published as Journal of Pharmacokinetics and Biopharmaceutics.

In this issue (11 articles)

  1. No Access

    Original Paper

    Population pharmacokinetic/pharmacodynamic modelling of the anti-TNF-α polyclonal fragment antibody AZD9773 in patients with severe sepsis

    James W. T. Yates, Shampa Das… Pages 591-599
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  2. No Access

    Original Paper

    Modeling of Functional Assessment Questionnaire (FAQ) as continuous bounded data from the ADNI database

    K. Ito, M. M. Hutmacher, B. W. Corrigan Pages 601-618
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  3. No Access

    Original Paper

    Longitudinal FEV1 dose–response model for inhaled PF-00610355 and salmeterol in patients with chronic obstructive pulmonary disease

    Jace C. Nielsen, Matthew M. Hutmacher… Pages 619-634
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  4. No Access

    Original Paper

    A population pharmacokinetic model for the complex systemic absorption of ropivacaine after femoral nerve block in patients undergoing knee surgery

    François Gaudreault, Pierre Drolet… Pages 635-642
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  5. No Access

    Original Paper

    Bench to bedside translation of antibody drug conjugates using a multiscale mechanistic PK/PD model: a case study with brentuximab-vedotin

    Dhaval K. Shah, Nahor Haddish-Berhane… Pages 643-659
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  6. No Access

    Original Paper

    Optimised protocol design for the screening of analgesic compounds in neuropathic pain

    A. Taneja, J. Nyberg, M. Danhof… Pages 661-671
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  7. No Access

    Original Paper

    Application of ED-optimality to screening experiments for analgesic compounds in an experimental model of neuropathic pain

    A. Taneja, J. Nyberg, E. C. M. de Lange… Pages 673-681
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  8. No Access

    Original Paper

    Application of PBPK modeling to predict monoclonal antibody disposition in plasma and tissues in mouse models of human colorectal cancer

    Lubna Abuqayyas, Joseph P. Balthasar Pages 683-710
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  9. No Access

    Original Paper

    Applications of minimal physiologically-based pharmacokinetic models

    Yanguang Cao, William J. Jusko Pages 711-723
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  10. No Access

    Commentary

    Letter to the editor regarding: “A reduction in between subject variability is not mandatory for selecting a new covariate”

    Mats O. Karlsson, Martin Bergstrand Pages 725-726
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  11. Commentary

    Reply to the editor of Journal of Pharmacokinetics and Pharmacodynamics

    Chakradhar V. Lagishetty, Pavan Vajjah… Page 727
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