1. Preface

   • Armin Distler
   • Wolfgang Meyer-Sabellek

   EditorialNotes Pages: S1 - S1

2. What blood pressure levels should be treated?

   • A. Zanchetti

   Pathophysiology Pages: S2 - S6

3. The role of α- and β-adrenoceptor blockade in antihypertensive treatment

   • P. A. van Zwieten

   Pathophysiology Pages: S7 - S12

4. Oral administration of carvedilol and prazosin inhibits the prostaglandin F_2α- and noradrenaline-induced contraction of human hand veins in vivo

   • C. Beermann
   • J. Schloos
   • G. G. Belz

   Pathophysiology Pages: S13 - S19

5. Pharmacological profile of β-adrenoceptor blockers with vasodilating properties, especially carvedilol — rationale for clinical use

   • G. Sponer
   • W. Bartsch
   • K. Strem

   Clinical Pharmacology Pages: S20 - S26

6. Clinical pharmacology of carvedilol

   • B. Tomlinson
   • B. N. C. Prichard
   • R. J. Walden

   Clinical Pharmacology Pages: S27 - S36

7. Antihypertensive effect of carvedilol: a preliminary dose-response study

   • B. Casadei
   • J. Conway
   • R. Bird

   Clinical Pharmacology Pages: S37 - S38

8. Clinical experience with dual-acting drugs in hypertension

   • K. H. Rahn

   Clinical Pharmacology Pages: S39 - S42

9. Antihypertensive profile of carvedilol

   • W. Meyer-Sabellek
   • B. Agrawal

   Antihypertensive Therapy Pages: S43 - S52

10. Comparison of the antihypertensive effects of carvedilol and metoprolol on resting and exercise blood pressure

    • I. -W. Franz
    • B. Agrawal
    • R. Ketelhut

    Antihypertensive Therapy Pages: S53 - S57

11. Long-term hemodynamic effects of antihypertensive treatment

    • P. Lund-Johansen
    • P. Omvik
    • J. E. Nordrehaug

    Antihypertensive Therapy Pages: S58 - S64

12. Hemodynamic and metabolic effects of carvedilol: a meta-analysis approach

    • U. Stienen
    • W. Meyer-Sabellek

    Antihypertensive Therapy Pages: S65 - S72

13. Pathophysiology and triggers of acute myocardial infarction: clinical implications

    • S. N. Willich
    • A. H. Jimenez
    • J. E. Muller

    Carvedilol and The Heart Pages: S73 - S78

14. Left ventricular hypertrophy regression during antihypertensive treatment

    • H. Eichstaedt
    • O. Danne
    • D. Kreuz

    Carvedilol and The Heart Pages: S79 - S86

15. Therapeutic effect on left ventricular hypertrophy by different antihypertensive drugs

    • W. Motz
    • B. E. Strauer

    Carvedilol and The Heart Pages: S87 - S92

16. Acute hemodynamic effects of carvedilol in comparison with propranolol in patients with coronary heart disease

    • T. Wendt

    Carvedilol and The Heart Pages: S93 - S97

17. Can intravenous beta blockade predict long-term haemodynamic benefit in chronic congestive heart failure secondary to ischaemic heart disease? A comparison between intravenous and oral carvedilol

    • P. DasGupta
    • A. Lahiri

    Carvedilol and The Heart Pages: S98 - S104

18. Effects of carvedilol on adrenergic receptor pharmacology in human ventricular myocardium and lymphocytes

    • M. R. Bristow
    • P. Larrabee
    • J. D. Port

    Carvedilol and The Heart Pages: S105 - S113

19. Clinical relevance of albuminuria in hypertensive patients

    • E. Ritz
    • D. Fliser

    Carvedilol and The Kidney Pages: S114 - S119

20. Influence of antihypertensive therapy on renal function

    • U. Frei
    • R. Schindler
    • K. M. Koch

    Carvedilol and The Kidney Pages: S120 - S126

21. Carvedilol and the kidney

    • A. G. Dupont

    Carvedilol and The Kidney Pages: S127 - S131