1. Important announcement

   Announcement Pages: 1 - 1

2. Introduction

   • William B. Guggino

   EditorialNotes Pages: 5 - 6

3. Spectrum of mutations in cystic fibrosis

   • Garry R. Cutting

   OriginalPaper Pages: 7 - 10

4. Effects of the ΔF508 mutation on the structure, function, and folding of the first nucleotide-binding domain of CFTR

   • Philip J. Thomas
   • Peter L. Pedersen

   OriginalPaper Pages: 11 - 19

5. CFTR targeting in epithelial cells

   • Andrew P. Morris
   • Sonia A. Cunningham
   • Raymond A. Frizzell

   OriginalPaper Pages: 21 - 26

6. Outwardly rectifying chloride channels and CF: A divorce and remarriage

   • William B. Guggino

   OriginalPaper Pages: 27 - 35

7. Prospects for virus-based gene therapy for cystic fibrosis

   • Terence R. Flotte

   OriginalPaper Pages: 37 - 42

8. Ionic channels in the plasma membrane ofSchizosaccharomyces pombe: Evidence from patch-clamp measurements

   • Vladimír Vacata
   • Milan Höfer
   • Harold Lecar

   Original Article Pages: 43 - 53

9. Solubilization and reconstitution of the mitochondrial peptide-sensitive channel

   • Florence Fèvre
   • Jean-Pierre Henry
   • Michel Thieffry

   Original Article Pages: 55 - 60

10. Phosphorylation of the Na,K-ATPase by Ca,phospholipid-dependent andcAMP-dependent protein kinases. Mapping of the region phosphorylated by Ca,phospholipid-dependent protein kinase

    • A. V. Chibalin
    • O. D. Lopina
    • L. A. Vasilets

    Original Article Pages: 61 - 66