1. Editorial

   • Garland R. Marshall
   • Andy Vinter

   Legacy Pages: 1 - 1

2. Prediction of the three-dimensional structure of the human Fas receptor by comparative molecular modeling

   • Jürgen Bajorath
   • Alejandro Aruffo

   OriginalPaper Pages: 3 - 8

3. Molecular modeling of the neurophysin I/oxytocin complex

   • R. Kazmierkiewicz
   • C. Czaplewski
   • J. Ciarkowski

   OriginalPaper Pages: 9 - 20

4. Development of a common 3D pharmacophore for δ-opioid recognition from peptides and non-peptides using a novel computer program

   • Ping Huang
   • Susan Kim
   • Gilda Loew

   OriginalPaper Pages: 21 - 28

5. Optimizing doped libraries by using genetic algorithms

   • Dirk Tomandl
   • Andreas Schober
   • Andreas Schwienhorst

   OriginalPaper Pages: 29 - 38

6. Strategies for the determination of pharmacophoric 3D database queries

   • John H. Van Drie

   OriginalPaper Pages: 39 - 52

7. A hybrid approach for addressing ring flexibility in 3D database searching

   • Jens Sadowski

   OriginalPaper Pages: 53 - 60

8. MM3(96) parameterization for camptothecin analogs: An ab initio and molecular mechanics study

   • Sean W. Carrigan
   • Jenn-Huei Lii
   • J. Phillip Bowen

   OriginalPaper Pages: 61 - 70

9. Comparative molecular field analysis and molecular modeling studies of 20-(S)- camptothecin analogs as inhibitors of DNA topoisomerase I and anticancer/antitumor agents

   • Sean W. Carrigan
   • Peter C. Fox
   • J. Phillip Bowen

   OriginalPaper Pages: 71 - 78

10. MS-WHIM, new 3D theoretical descriptors derived from molecular surface properties: A comparative 3D QSAR study in a series of steroids

    • Gianpaolo Bravi
    • Emanuela Gancia
    • Andrea Zaliani

    OriginalPaper Pages: 79 - 92

11. Objective models for steroid binding sites of human globulins

    • Jurgen Schnitker
    • Ramesh Gopalaswamy
    • Gordon M. Crippen

    OriginalPaper Pages: 93 - 110