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Reactions of 2-Acetyl-5-hydroxy-5-methyl-3-phenylcyclohexanone and Alkyl 4-Hydroxy-4-methyl-2-oxo-6-phenylcyclohexanecarboxylates with Nucleophilic Reagents

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Abstract

A series of novel enamines, bis(enamines), benzisoxazoles, tetrahydroindazoles, benzophenone hydrazones were obtained via reactions of 2-acetyl-5-hydroxy-5-methylcyclohexanone and alkyl 4-hydroxy-4-methyl-2-oxocyclohexanecarboxylates with nucleophilic reagents such as aliphatic and aromatic amines, diamines, hydroxylamine, hydrazine, phenylhydrazine, benzophenone hydrazone. The structures of the compounds obtained were proved by IR and 1H NMR spectroscopy methods.

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Acknowledgments

The studies were performed with use of the equipment of the Resource Educational “Center Chemistry” of the Science Park of St. Petersburg State University.

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Authors and Affiliations

  1. Perm State Pharmaceutical Academy, ul. Polevaya 2, Perm, 614990, Russia

    V. L. Gein, N. V. Nosova, A. V. Vagapova & N. V. Dozmorova

  2. St. Petersburg State University, St. Petersburg, Russia

    A. N. Yankin

Authors
  1. V. L. Gein
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  2. N. V. Nosova
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  3. A. V. Vagapova
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  4. N. V. Dozmorova
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  5. A. N. Yankin
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Corresponding author

Correspondence to V. L. Gein.

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Russian Text © The Author(s), 2019, published in Zhurnal Obshchei Khimii, 2019, Vol. 89, No. 7, pp. 987–994.

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Gein, V.L., Nosova, N.V., Vagapova, A.V. et al. Reactions of 2-Acetyl-5-hydroxy-5-methyl-3-phenylcyclohexanone and Alkyl 4-Hydroxy-4-methyl-2-oxo-6-phenylcyclohexanecarboxylates with Nucleophilic Reagents. Russ J Gen Chem 89, 1353–1359 (2019). https://doi.org/10.1134/S1070363219070016

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  • DOI: https://doi.org/10.1134/S1070363219070016

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