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Complexes of nucleic acids with oppositely charged amphiphilic ions in aqueous and organic solutions

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Abstract

The published data on the interaction of DNA macromolecules with cationic amphiphiles (surfactants) are analyzed. The effect of the structure of surfactant molecules on their interaction with DNA and the structure of DNA-surfactant complexes is examined. The unique property of DNA molecules to preserve the double-helix conformation in complexes is considered. The structure of DNA-surfactant complexes in aqueous and organic solutions is discussed, and examples of the possible application of these complexes are presented.

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Original Russian Text © O.A. Pyshkina, V.G. Sergeyev, 2012, published in Vysokomolekulyarnye Soedineniya, Ser. C, 2012, Vol. 54, No. 7, pp. 1013–1022.

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Pyshkina, O.A., Sergeyev, V.G. Complexes of nucleic acids with oppositely charged amphiphilic ions in aqueous and organic solutions. Polym. Sci. Ser. C 54, 48–56 (2012). https://doi.org/10.1134/S1811238212060033

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