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Are Personality Disorders Psychological Manifestations of Executive Function Deficits? Bivariate Heritability Evidence from a Twin Study

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Abstract

This study tested whether personality disorders may be the psychological manifestations of executive function deficits by examining their bivariate heritability in a community sample of 314 twins (ages 5–17 years; M age = 9.7; 96 monozygotic pairs and 61 dizygotic pairs). The parents of the twins completed the Coolidge Personality and Neuropsychological Inventory (Coolidge, 1998; Coolidge et al., 2002). Heritability was estimated by structural equation modeling. Executive function deficits and personality disorders were significantly heritable (executive function deficits, .77; 11 out of 12 personality disorders, median = .69). The proportion of the observed correlation attributable to heritable factors or bivariate heritability between executive function deficits and the personality disorder scales ranged from .27 for schizoid to .64 for histrionic. These findings may provide some insight as to why individuals diagnosed with specific personality disorders frequently exhibit chronic difficulties with everyday decisions, selective attention and inhibition, judgments, choices, planning, and flexibility.

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References

  • Akaike, H. (1987). Factor analysis and AIC. Psychometrika 52: 317-332.

    Google Scholar 

  • Alexander, G. E., DeLong, M. R., and Strick, P. L. (1986). Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Annu. Rev. Neurosci. 9:357-381.

    Google Scholar 

  • American Psychiatric Association (1994). Diagnostic and statistical manual of mental disorders, 4th ed. Washington DC: Author.

  • Andrulonis, P. A., Glueck, B. C., Stoebel, C. F., and Vogel, N. G. (1980). Organic brain dysfunction and the borderline syndrome. Psychiatr. Clin. North Am. 4:47-66.

    Google Scholar 

  • Barkley, R. A. (2001). The executive functions and self-regulations: An evolutionary neuropsychological perspective. Neuropsychol. Rev. 11:1-29.

    Google Scholar 

  • Bernstein, D., Cohen, P., Skodol, A., Bezirganian, S., and Brook, J. (1996). Childhood antecedents of adolescent personality disorders. Am. J. Psychol. 15:907-913.

    Google Scholar 

  • Bleiberg, E. (2001). Treating personality disorders in children and adolescents. New York: Guilford Press.

    Google Scholar 

  • Chow, T. W., and Cummings, J. L. (1999). Frontal-subcortical circuits. In: B. L. Miller and J. L. Cummings (eds.), The human frontal lobes. New York: Guilford Press.

    Google Scholar 

  • Cohen, D. J., Dibble, E., Grawe, J. M., and Pollin, W. (1975). Reliably separating identical from fraternal twins. Arch. Gen. Psychol. 135:1371-1375.

    Google Scholar 

  • Coolidge, F. L. (1998). Coolidge Personality and Neuropsychological Inventory for Children (CPNI): Manual. Colorado Springs, CO: Author.

  • Coolidge, F. L., Aksamit, C. R., and Becker, L. A. (1994). Prediction of recidivism in juvenile offenders. Indian J. Psychol. Issues 2:1-6.

    Google Scholar 

  • Coolidge, F. L., Philbrick, P. B., Wooley, M. J., Bunting, E. K., Hyman, J. N., and Stager, M. A. (1990). The KCATI: Development of an inventory for the assessment of personality disorders in children. J. Pers. Clin. Studies 6:225-232.

    Google Scholar 

  • Coolidge, F. L., Reilman, B. J., Becker, L. A., Cass, V. J., and Coolidge, R. L. (1992). Emotional problems and neuropsychological symptoms in juvenile non-violent offenders. J. Pers. Clin. Studies 8:7-13.

    Google Scholar 

  • Coolidge, F. L., and Segal, D. L. (1998). Evolution of personality disorder diagnosis in The Diagnostic and Statistical Manual of Mental Disorders. Clin. Psychol. Rev. 18:585-599.

    Google Scholar 

  • Coolidge, F. L., Segal, D. L., Stewart, S. E., and Ellett, J. A. C. (2000). Neuropsychological dysfunction in children with borderline personality disorder features: A preliminary investigation. J. Research Pers. 34:554-561.

    Google Scholar 

  • Coolidge, F. L., Thede, L. L., and Jang, K. L. (2001). Heritability of personality disorders in childhood. J. Pers. Disord. 15:33-40.

    Google Scholar 

  • Coolidge, F. L., Thede, L. L., Stewart, S. E., and Segal, D. L. (2002). The Coolidge Personality and Neuropsychological Inventory for Children (CPNI): Preliminary psychometric characteristics. Behav. Mod. 26:550-566.

    Google Scholar 

  • Coolidge, F. L., Thede, L. L., and Young, S. E. (2000). Heritability and the comorbidity of ADHD with behavioral disorders and executive functions deficits: A preliminary investigation. Dev. Neuropsychol. 17:273-287.

    Google Scholar 

  • Damasio, A. R., Tranel, D., and Damasio, H. C. (1991). Somatic markers and the guidance of behavior: Theory and preliminary testing. In: H. S. Levin, H. M. Eisenberg, and A. L. Benton (eds.), Frontal lobe function and dysfunction. New York: Oxford University Press.

    Google Scholar 

  • Deckel, A. W., Hesselbrock, V., and Bauer, L. (1996). Antisocial personality disorder, childhood delinquency, and frontal brain functioning: EEG and neuropsychological findings. J. Clin. Psychol. 52:639-650.

    Google Scholar 

  • Elliott, C., and Gillett, G. (1992). Moral insanity and practical reason. Philosophical Psychol. 5:53-67.

    Google Scholar 

  • Eysenck, H. J. (1964). Crime and personality. Boston: Houghton Mifflin.

    Google Scholar 

  • Friedman, M. C. (1998). The Coolidge Axis II Inventory for children as a measure of attention-deficit/hyperactivity disorder and comorbid disorders. Unpublished master's thesis, University of Colorado, Colorado Springs, CO.

  • Gardner, D. L., Lucas, P. N., and Cowdry, R. W. (1987). Soft sign neurological abnormalities in borderline personality disorder and normal control subjects. J. Nerv. Ment. Dis. 175:177-180.

    Google Scholar 

  • Gioia, G. A., Isquith, P. K., Guy, S. C., and Kenworthy, L. (2000). Behavior rating inventory of executive function. Child Neuropsychol. 6:235-238.

    Google Scholar 

  • Hersen, M., and Van Hasselt, V. B. (eds.) (2001). Advanced abnormal psychology. New York: Kluwer Academic/Plenum Publishers.

    Google Scholar 

  • Hetherington, E. M., Reiss, D., and Plomin, R. (eds.) (1994). Separate social worlds of siblings: Impact of nonshared environment on development. Hillsdale, NJ: Erlbaum.

    Google Scholar 

  • Jang, K. L., Livesley, W. J., Vernon, P. A., and Jackson, D. N. (1996). Heritability of personality disorder traits: A twin study. Acta Psychol. Scand. 94:438-444.

    Google Scholar 

  • Jöreskog, K. G., and Sörbom, D. (1993). PRELIS 2, A Preprocessor for LISREL. Chicago: Scientific Software International.

    Google Scholar 

  • Kernberg, P. F., Weiner, A. S., and Bardenstein, K. K. (2000). Personality disorders in children and adolescents. New York: Basic Books.

    Google Scholar 

  • Kimble, C. R., Oepen, G., Weinberg, E., Williams, A. A., and Zanarini, M. C. (1997). Neurological vulnerability and trauma in borderline personality disorder. In: M. C. Zanarini (ed.), Role of sexual abuse in the etiology of borderline personality disorder (pp. 165-180). Washington, DC: American Psychiatric Press.

    Google Scholar 

  • Lezak, M. D. (1982). The problem of assessing executive functions. Int. J. Psychol. 17:281-297.

    Google Scholar 

  • Livesley, W. J. (ed.) (1995). The DSM-IV personality disorders. New York: The Guilford Press.

    Google Scholar 

  • Livesley, W. J., Jang, K. L., Jackson, D. N., and Vernon, P. A. (1993). Genetic and environmental contributions to dimensions of personality disorder. Am. J. Psychol. 150:1826-1831.

    Google Scholar 

  • Luria, A. R. (1966). Higher cortical function in man. New York: Basic Books.

    Google Scholar 

  • Lykken, D. T. (1957). A study of anxiety in the sociopathic personality. J. Abnorm. Soc. Psychol. 55:6-10.

    Google Scholar 

  • MacPherson, S. E., Phillips, L. H., and Della Sala, S. (2002). Age, executive function and social decision-making: A dorsolateral prefrontal theory of cognitive aging. Psychol. Aging, 17, 598-609.

    Google Scholar 

  • Middleton, F. A., and Strick, P. L. (2001). A revised neuroanatomy of frontal-subcortical circuits. In: D. G. Lichter and J. L. Cummings (eds.), Frontal-subcortical circuits in psychiatric and neurological disorders. New York: Guilford Press.

    Google Scholar 

  • Millon, T., and Davis, R. D. (1996). Disorders of personality: DSMIV and beyond. New York: Wiley & Sons.

    Google Scholar 

  • Millon, T., Davis, R., Millon, C., Escovar, L., and Meagher, S. (2000). Personality disorders in modern life. New York: John Wiley & Sons, Inc.

    Google Scholar 

  • Murray, M. E. (1979). Minimal brain dysfunction and borderline personality adjustment. Am. J. Psychother. 33:391-403.

    Google Scholar 

  • Neale, M. C., Boker, S. M., Xie, G., and Maes, H. H. (1999). Mx: statistical modeling, 5th ed., Box 126 MCV, Department of Psychiatry, Richmond, VA 23298.

    Google Scholar 

  • Neale, M. C., and Cardon, L. R. (1992). Methodology for genetic studies of twins and families. Dordrecht: Kluwer.

    Google Scholar 

  • Pennington, B. F. (2002). The development of psychopathology. New York: Guilford Press.

    Google Scholar 

  • Pennington, B. F., and Ozonoff, S. (1996). Executive functions and developmental psychopathology. J. Child Psychol. Psychiatry 37:51-87.

    Google Scholar 

  • Quitkin, F., Rifkin, A., and Klein, D. F. (1976). Neurological soft signs in schizophrenia and character disorders. Arch. Gen. Psychiatry 33:845-853.

    Google Scholar 

  • Raine, A., Sheard, C., Reynolds, G. P., and Lencz, T. (1992). Prefrontal structural and functional deficits associated with individual differences in schizotypal personality. Schizophr. Res. 7:237-247.

    Google Scholar 

  • Rowe, D. C. (1994). The limits of family influence: Genes, experience, and behavior. New York: Guilford Press.

    Google Scholar 

  • Sarazin, M., Pillon, B., Giannakopoulos, P., Rancurel, G., Samson, Y., and Dubois, B. (1998). Clinicometabolic dissociation of cognitive functions and social behavior in frontal lobe lesions. Am. Acad. Neurol. 51:142-148.

    Google Scholar 

  • Shallice, T., and Burgess, W. (1991). Deficits in strategy application following frontal lobe damage in man. Brain 114:727-741.

    Google Scholar 

  • Silver, C. H., Benton, S. B., Goulden, L. G., Molho, C. E., and Clark, J. P. (1999, August). Measurement of children's executive functioning by parent report. Paper presented at the meeting of the American Psychological Association, Boston, MA.

  • Soloff, P. H., and Millward, J. W. (1983). Developmental histories of borderline patients. Comprehensive Psych. 24:574-588.

    Google Scholar 

  • Stone, A. A., Turkkan, J. S., Bachrach, C. A., Jobe, J. B., Kurtzman, H. S., and Cain, V. S. (eds.) (2000). The science of self-report: Implications for research and practice. Mahwah, NJ: Erlbaum.

    Google Scholar 

  • Thede, L. L., and Coolidge, F. L. (2002, August). Executive function deficits in Asperger disorder. Paper presented to the American Psychological Association, Chicago, IL.

  • Torgersen, S., Lygren, S., Oien, P. A., Skre, I., Onstad, S., Edvardsen, J., Tambs, K., and Kringlen, E. (2000). A twin study of personality disorders. Compr. Psychiatry 41:416-425.

    Google Scholar 

  • van Reekum, R. (1993). Acquired and developmental brain dysfunction in borderline personality disorder. Can. J. Psychiatry 38(Suppl. 1):4-9.

    Google Scholar 

  • Verhulst, F. C. (1984). Diagnosing borderline children. Acta Paedopsychiatr. 50:161-173.

    Google Scholar 

  • Welsh, M. C., and Pennington, B. F. (1988). Assessing frontal lobe functioning in children: Views from developmental psychology. Dev. Neuropsychol. 4:199-230.

    Google Scholar 

  • Wolff, S. (1993). Personality disorder in childhood. In: P. Tyrer and G. Stein (eds.), Personality disorder reviewed (pp. 64-89). Glasgow: Bell & Bain Limited.

    Google Scholar 

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Authors and Affiliations

  1. University of Colorado, Colorado Springs

    Frederick L. Coolidge & Linda L. Thede

  2. University of British Columbia, Vancouver, Canada

    Kerry L. Jang

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  1. Frederick L. Coolidge
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Coolidge, F.L., Thede, L.L. & Jang, K.L. Are Personality Disorders Psychological Manifestations of Executive Function Deficits? Bivariate Heritability Evidence from a Twin Study. Behav Genet 34, 75–84 (2004). https://doi.org/10.1023/B:BEGE.0000009486.97375.53

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  • DOI: https://doi.org/10.1023/B:BEGE.0000009486.97375.53

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