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Teriparatide treatment of osteoporosis in a patient with anorexia nervosa

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Abstract

Osteoporosis commonly occurs in patients with anorexia nervosa (AN) and is often irreversible even after weight restoration. We describe a 52-year-old woman with AN and severe osteoporosis, discovered after she sustained multiple fractures from a fall. She had low weight for most of her life, but was only formally diagnosed with AN 6 years prior to her presentation. She received therapy for her eating disorder and was able to restore weight, which led to a 4.1 % improvement in her bone density. We then treated her with teriparatide for 2 years, which lead to a further 21 % increase in bone density and she has had no recurrence of fractures. Since AN-associated osteoporosis is characterized by low bone formation, teriparatide may be a useful treatment option.

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The authors have no conflict of interest to disclose.

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Authors and Affiliations

  1. Division of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine, University of Iowa Carver College of Medicine, E 426 GH, 200 Hawkins Drive, Iowa City, IA, 52242, USA

    Amal Shibli-Rahhal

  2. Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, IA, USA

    Laurie McCormick

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  1. Amal Shibli-Rahhal
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  2. Laurie McCormick
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Correspondence to Amal Shibli-Rahhal.

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Shibli-Rahhal, A., McCormick, L. Teriparatide treatment of osteoporosis in a patient with anorexia nervosa. Eat Weight Disord 18, 229–231 (2013). https://doi.org/10.1007/s40519-013-0034-y

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  • DOI: https://doi.org/10.1007/s40519-013-0034-y

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