Abstract
This study examined the associations of dietary glycemic index and glycemic load with glucose intolerance in Iranian adults. The study had a cross-sectional design and was performed as a secondary analysis on data obtained from the Isfahan Healthy Heart Program (2000–2001). Data on food intake using a 24-hour recall and blood parameters of a subsample of 960 adults age ≥19 years were used (436 Men, 524 Women; age: 38.2 ± 15.4 year). We identified a positive significant association of fasting and postprandial blood glucose (P < 0.001), body mass index (P < 0.001), and age (P < 0.001) with diabetes mellitus, but found no statistically significant associations of dietary glycemic index and glycemic load with diabetes mellitus after adjusting for body mass index, age, gender, and smoking as confounding factors. We concluded that a low glycemic index diet is not associated with the prevalence of glucose intolerance in our sample.
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References
Schalkwijk CG, Stehouwer CDA. Vascular complications in diabetes mellitus: the role of endothelial dysfunction. Clin Sci. 2005;109:143–59.
Votey Scott R, Peters A. Diabetes mellitus, Type 2 (A Review). eMedicine 2007. www.emedicine.medscape.com/article/766143-overview. Accessed 12 Nov 2007.
Wild S, Bchir MB, Gojka R, Green A, Richard SR, King H. Global prevalence of diabetes. Diabetes Care. 2004;27:1047–53.
Azizi F. Epidemiology of diabetes in Iran. Proceedings of symposium of new horizons in education and treatment of diabetes. Tehran, Iran; 2001. pp 7–9.
Navaye L, Kimiagar M, Azizi F. Prevalence of diabetes mellitus and IGT in Islamshahr; a comparison between OGTT and screening efficacy to diagnose glucose metabolism disorder. Res Med. 1997;21:85–96.
Larijani B, Zahedi F, Aghakhani S. Epidemiology of diabetes mellitus in Iran. Shiraz E-Med J. 2003;4:1–7.
Khan A, Safdar M. Role of diet, nutrients, spices and natural products in diabetes mellitus. Pak J Nutr. 2003;2:1–12.
Schenk S, Davidson CJ, Zderic TW, Byerley LO, Edward F, Coyle EF. Different glycemic indexes of breakfast cereals are not due to glucose entry into blood but to glucose removal by tissue. Am J Clin Nutr. 2003;78:742–8.
Sheard NF, Clarck NG, Brand-Miller JC, Franz MJ, Pi-Sunyer FX, Mayer-Davis E, et al. Dietary carbohydrate (amount and type) in the prevention and management of diabetes. Diabetes Care. 2004;27:2266–71.
Hu FB, van Dam RM, Liu S. Diet and risk of type II diabetes: the role of types of fat and carbohydrate. Diabetologia. 2001;44:805–17.
Schulze MB, Liu S, Rimm EB, Manson JE, Willett WC, Hu FB. Glycemic index, glycemic load, and dietary fiber intake and incidence of type 2 diabetes in younger and middle-aged women. Am J Clin Nutr. 2004;80:348–56.
Jenkins DJ, Wolever TM, Taylor RH, Barker H, Fielden H, Baldwin JM, et al. Glycemic index of foods: a physiological basis for carbohydrate exchange. Am J Clin Nutr. 1981;34:362–6.
Willett W, Manson J, Liu S. Glycemic index, glycemic load, and risk of type 2 diabetes. Am J Clin Nutr. 2002;76:274S–80S.
Hodge AM, English DR, O’Dea K, Giles GG. Glycemic index and dietary fiber and the risk of type 2 diabetes. Diabetes Care. 2004;27:2701–6.
Meyer KA, Kushi LH, Jacobs DR, Slavin J, Sellers TA, Folsom AR. Carbohydrates, dietary fiber, and incidence of type 2 diabetes in older women. Am J Clin Nutr. 2000;71:921–30.
Beaglehole R, Bonita R, Horton R, Adams C, Alleyne G, Asaria P, et al. Priority actions for the non-communicable disease crisis. Lancet. 2011;377:1438–47.
Sarraf-Zadegan N, Baghaei A, Sadri G, Kelishadi R, Malekafzali H, Boshtam M, et al. Isfahan healthy heart program: evaluation of comprehensive, community-based interventions for non-communicable disease prevention. Prev Control. 2006;2:73–84.
WHO. Diet, nutrition and the prevalence of chronic diseases. http://www.who.int/dietphysicalactivity/publications/trs916/en/.
The Merck Manual. http://www.merckmanuals.com/professional/endocrine_and_metabolic_disorders/diabetes_mellitus_anddisordersofcarbohydratemetabolism/diabetesmellitusdm.html?qt=2007%20and%20diagnostic&alt=sh#v988339 (2007). Accessed 20 Jan 2007.
Mirmiran P. The principles of food programs regulation. 1st ed. Persian: The Organization of Special Diseases Affairs; 1999. p. 12–25.
Ghaffar Pour M, Hoshyar Rad A, Kianfar H. The guideline for home measurements, conversion coefficients and the percentage of uneatable part in food stuffs. 1st ed. Persian: Agricultural Science; 1999. p. 5–24.
Taleban FA, Esmaieli M. The Glycemic index of Iranian foods. 1st ed. Persian: Medical Sciences University of Shahid Beheshti and Iran’s Institute of Nutritional Research and Food Industries; 1999. p. 12–30.
Mahan LK, Escott-Stump S. Krause’s food, nutrition and diet Therapy. 12th ed. Philadelphia: W B Saunders Co; 2012.
Mouahedi A, Roosta R. Food composition table; complied and translated. Iran’s Institute of Nutritional Research and Food Industries; 1999 (translated in Persian).
Van Dam RM, Dekker JM, Nijpels G, Stehouwer CDA, Bouter LM, Heine RJ. Coffee consumption and incidence of impaired fasting glucose, impaired glucose tolerance, and type 2 diabetes: the Hoorn Study. Diabetologia. 2004;47:2152–9.
Rizkalla SW, Taghrid L, Laromiguiere M, Huet D, Boillot J, Rigoir A, et al. Improved plasma glucose control, whole body glucose utilization, and lipid profile on a low glycemic index diet in type 2 diabetic men: a randomized controlled trial. Diabetes Care. 2004;27:1866–72.
Murakami K, Sasaki S, Takahashi Y, Okubo H, Hosoi Y, Horiguchi H, et al. Dietary glycemic index and load in relation to metabolic risk factors in Japanese female farmers with traditional dietary habits. Am J Clin Nutr. 2006;83:1161–9.
Brand-Miller J, Hayne S, Petocz P, Colagiuri S. Low-glycemic index diets in the management of diabetes. Diabetes Care. 2003;26:2261–7.
Gaesser GA. Carbohydrate quantity and quality in relation to body mass index. J Am Diet Assoc. 2007;107:1768–80.
Hu G, Lindstro¨m J, Valle TT, Eriksson JG, Jousilahti P, Silventoinen K, et al. Physical activity, body mass index, and risk of type 2 diabetes in patients with normal or impaired glucose regulation. Arch Intern Med. 2004;164:892–6.
LaMonte MJ, Blair SN, Church TS. Physical activity and diabetes prevention. J Appl Physiol. 2005;99:1205–13.
Steyn NP, Nel JH, Nantel G, Kennedy G, Labadarios D. Food variety and dietary diversity scores in children: are they good indicators of dietary adequacy? Public Health Nutr. 2006;9:644–50.
Schatzkin A, Kipnis V, Carroll RJ, Midthune D, Subar AF, Bingham S, et al. A comparison of a food frequency questionnaire with a 24-hour recall for use in an epidemiological cohort study: results from the biomarker-based observing protein and energy nutrition (OPEN) study. Int J Epidemiol. 2003;32:1054–62.
Yamaji T, Mizoue T, Tabata S, Ogawa S, Yamaguchi K, Shimizu E, et al. Coffee consumption and glucose tolerance status in middle-aged Japanese men. Diabetologia. 2004;47:2145–51.
Acknowledgments
We would like to thank Isfahan Cardiovascular Research Centre (ICRC), Isfahan University of Medical Sciences, Isfahan, Iran, for providing data for this study.
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The authors declare no conflicts of interest. All authors contributed equally in designing and coordinating the study. All authors have read and approved the content of the manuscript.
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Hosseini, E., Lachat, C., Mohammadifard, N. et al. Associations of dietary glycemic index and glycemic load with glucose intolerance in Iranian adults. Int J Diabetes Dev Ctries 34, 89–94 (2014). https://doi.org/10.1007/s13410-013-0158-7
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DOI: https://doi.org/10.1007/s13410-013-0158-7