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Myxoglobulosis of Appendix A Rare Entiy

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Abstract

We describe a case of the extremely rare entity of myxoglobulosis of the appendix in an 18-year-old man who underwent laparoscopic appendectomy with the clinical diagnosis of recurrent appendicitis. Transaction of the appendix after ligation resulted in extrusion of numerous whitish egg-like globules ranging in size from 0.2 to 0.7 cm in diameter. It was initially thought to be hydatid of appendix, resulting in emergent usage of povidine iodine as scolicidal after suction of all the cysts/eggs. On microscopic examination, the globules consisted of faintly eosinophilic laminations of mucin surrounding an amorphous granular core were found. The mucin was identified by positivity with histochemical mucin stains. After thorough microscopic examination of the appendix, our case was diagnosed as myxoglobulosis due to mucosal hyperplasia, associated with luminal obstruction with possibly a membrane.

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References

  1. Gonzalez JEG, Hann SE, Trujillo YP (1988) Myxoglobulosis of the appendix. Am J Surg Pathol 12:962–966

    Article  CAS  PubMed  Google Scholar 

  2. Lubin I, Berle E (1972) Myxoglobulosis of the appendix. Arch Pathol 94:533–536

    CAS  PubMed  Google Scholar 

  3. Rolon PA (1977) Myxoglobulosis of the appendix. Int Surg 62:355–356

    CAS  PubMed  Google Scholar 

  4. Rajman I, Leong S, Hassaram S, Marcon NE (1994) Appendiceal mucocele: endoscopic appearance. Endoscopy 26:326–328

    Article  Google Scholar 

  5. Madwed D, Mindelzun R, Jeffrey RB Jr (1992) Mucocele of the appendix: 11 imaging findings. Am J Radio 159:69–72

    CAS  Google Scholar 

  6. Issacs KL, Warshaner DM (1992) Mucocele of the appendix: computed tomographic, endoscopic and pathologic correlation. Am J Gastroenterol 87:787–789

    Google Scholar 

  7. Probstein JG, Lassar GN (1948) Mucocele of the appendix, with myxoglobulosis. Ann Surg 127(1):171–176

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  8. Collins DC (1955) A study of 50,000 specimens of the human vermiform appendix. Surg Gynecol Obstet 101:437–445

    CAS  PubMed  Google Scholar 

  9. Gonzalez JEG, Hann SE, Trujillo YP (1988) Myxoglobulosis of the appendix. Am J Surg Pathol 12(12):962–966

    Article  CAS  PubMed  Google Scholar 

  10. Lubin J, Berle E (1972) Myxoglobulosis of the appendix. Report of two cases. Arch Pathol 94(6):533–536

    CAS  PubMed  Google Scholar 

  11. Pai RK, Beck AH, Norton JA, Longacre TA (2009) Appendiceal mucinous neoplasms: clinicopathologic study of 116 cases with analysis of factors predicting recurrence. Am J Surg Pathol 33(10):1425–1439

    Article  PubMed  Google Scholar 

  12. Hollstrom E (1941) Myxoglobulosis appendicis. Acta Chir Scand 35:347–359

    Google Scholar 

  13. Viswanath YKS, Griffiths CDM, Shipsey D, Oriolowo A, Johnson SJ (1998) Myxoglobulosis, a rare variant of appendiceal mucocele, occurring secondary to an occlusive membrane. J R Coll Surg Edinb 43(3):204–206

    CAS  PubMed  Google Scholar 

  14. Huang HC, Lui IP, Jeng KS (1994) Intussusception of mucocele of appendix: a case report. Chin Med J 53:120–123

    CAS  Google Scholar 

  15. Brustmann H (2006) Myxoglobulosis of the appendix associated with a proximal carcinoid and a pseudodiverticulum. Ann Diagn Pathol 10(3):166–168

    Article  PubMed  Google Scholar 

  16. Guionmet N, Martí E, Bella MR, Moreno A (1990) Myxoglobulosis of the cecal appendix. Rev Esp Enferm Dig 77(5):365–367

    CAS  PubMed  Google Scholar 

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Correspondence to Biren Prasad Padhy.

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Padhy, B.P., Panda, S.K. Myxoglobulosis of Appendix A Rare Entiy. Indian J Surg 75 (Suppl 1), 337–339 (2013). https://doi.org/10.1007/s12262-012-0691-5

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  • DOI: https://doi.org/10.1007/s12262-012-0691-5

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