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Primary hepatic lymphoma in a patient with previous rectal adenocarcinoma: a case report and discussion of etiopathogenesis and diagnostic tools

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Abstract

Primary hepatic lymphoma is an extremely rare malignancy accounting for 0.016% of all cases of non-Hodgkin lymphomas. Approximately 1–4% of histologies described show a follicular pattern. We report a case of primary hepatic non-Hodgkin lymphoma that developed in a middle-aged woman 3 years after radical treatment (neoadjuvant chemoradiotherapy and surgery) for a rectal adenocarcinoma. Abdomen ultrasound showed a single nodule in the liver, which raised the issue of differential diagnosis with a metastasis from rectal cancer. After surgical removal of the nodule, histology revealed a primary B cell, stage IE follicular non-Hodgkin lymphoma, confined to the liver; indeed, no foci of lymphoma were found elsewhere in the body.

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Acknowledgments

We are grateful to Jean Ann Gilder (Scientific Communication srl) for revising and editing the text.

Conflict of interest

The authors declare that they have no conflict of interest.

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Authors and Affiliations

  1. Dipartimento di Endocrinologia ed Oncologia Molecolare e Clinica, Università di Napoli Federico II, Via Sergio Pansini 5, 80131, Naples, Italy

    Lucia Raimondo, Alfonso De Stefano, Chiara Alessandra Cella, Roberto Moretto & Chiara Carlomagno

  2. Dipartimento di Medicina Clinica e Sperimentale, Area di Ematologia, Università di Napoli Federico II, Naples, Italy

    Idalucia Ferrara & Amalia De Renzo

  3. Dipartimento di Scienze Biomorfologiche e Funzionali, Università di Napoli Federico II, Naples, Italy

    Francesco Paolo D’Armiento & Giuseppe Ciancia

Authors
  1. Lucia Raimondo
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  2. Idalucia Ferrara
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  3. Alfonso De Stefano
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  4. Chiara Alessandra Cella
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  5. Francesco Paolo D’Armiento
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  6. Giuseppe Ciancia
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  7. Roberto Moretto
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  8. Amalia De Renzo
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  9. Chiara Carlomagno
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Corresponding author

Correspondence to Chiara Carlomagno.

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Raimondo, L., Ferrara, I., De Stefano, A. et al. Primary hepatic lymphoma in a patient with previous rectal adenocarcinoma: a case report and discussion of etiopathogenesis and diagnostic tools. Int J Hematol 95, 320–323 (2012). https://doi.org/10.1007/s12185-012-1025-x

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  • DOI: https://doi.org/10.1007/s12185-012-1025-x

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