Abstract
Posterior reversible encephalopathy syndrome is a rare neuroradiologic condition associated with headache, seizures, altered sensorium, visual disturbances, and characteristic lesions on neuroimaging predominantly affecting the posterior regions of the brain. We report a 10-years-8-months-old girl who presented with headache, multiple seizures, and altered sensorium. Her blood pressure was 130/100 mmHg and left brachial pulse was not palpable. CT scan brain showed typical non-enhancing hypodensities in bilateral parieto-occiptal lobes. Prompt treatment of the hypertension led to rapid reversal of neurological symptoms. CT aortogram revealed aortoarteritis with bilateral renal artery stenosis.
Similar content being viewed by others
References
Hinchey J, Chaves C, Appignani B, Breen J, Pao L, Wang A et al. A reversible posterior leukoencephalopathy syndrome. N Engl J Med 1996; 334: 494–500.
Casey SO, Sampaio RC, Michel E, Truwit CL. Posterior reversible encephalopathy syndrome: utility of fluid-attenuated inversion recovery MR imaging in the detection of cortical and subcortical lesions. AJNR Am J Neuroradiol 2000; 21: 1199–1206.
Kerr GS, Hallahan CW, Giordano J, Leavitt RY, Fauci AS, Rottem M et al. Takayasu arteritis. Ann Intern Med 1994; 120: 919–929.
Mwipatayi BP, Jeffery PC, Beningfield SJ, Matley PJ, Naidoo NG, Kalla AA et al. Takayasu arteritis: clinical features and management: report of 272 cases. ANZ J Surg 2005; 75:110–117.
Singh S, Bali HK, Salaria M, Lal R, Pandav SS, Kumar L. Takayasu’s arteritis in young children: a potentially treatable condition. Indian Pediatr 1999; 36: 291–296.
Arend WP, Michel BA, Bloch DA, Hunder GG, Calabrese LH, Edworthy SM et al. The American College of Rheumatology 1990 criteria for the classification of Takayasu arteritis. Arthritis Rheum 1990; 33: 1129–1134.
Ito I. Medical treatment of Takayasu arteritis. Heart Vessels Suppl 1992; 7: 133–137.
Tyagi S, Khan AA, Kaul UA, Arora R. Percutaneous transluminal angioplasty for stenosis of the aorta due to aortic arteritis in children. Pediatr Cardiol 1999; 20: 404–410.
Muranjan MN, Bavdekar SB, More V, Deshmukh H, Tripathi M, Vaswani R. Study of Takayasu’s arteritis in children: clinical profile and management. J Postgrad Med 2000; 46: 3–8.
Kwon S, Koo J, Lee S. Clinical spectrum of reversible posterior leukoencephalopathy syndrome. Pediatr Neurol 2001; 24:361–364.
Garg RK. Posterior leukoencephalopathy syndrome. Postgrad Med J 2001; 77: 24–28.
Pavlakis SG, Frank Y, Chusid R. Hypertensive encephalopathy, reversible occipitoparietal encephalopathy, or reversible posterior leukoencephalopathy: three names for an old syndrome. J Child Neurol 1999; 14: 277–281.
Antunes NL, Small TN, George D, Boulad F, Lis E. Posterior leukoencephalopathy syndrome may not be reversible. Pediatr Neurol 1999; 20: 241–243.
Prasad N, Gulati S, Gupta RK, Kumar R, Sharma K, Sharma RK. Is reversible posterior leukoencephalopathy with severe hypertension completely reversible in all patients? Pediatr Nephrol 2003; 18: 1161–1166.
Striano P, Striano S, Tortora F, De Robertis E, Palumbo D, Elefante A et al. Clinical spectrum and critical care management of Posterior Reversible Encephalopathy Syndrome (PRES). Med Sci Monit 2005; 11: 549–553.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Karande, S., Jagtap, S. & Joshi, A. Posterior reversible encephalopathy syndrome revealing Takayasu’s arteritis. Indian J Pediatr 76, 218–220 (2009). https://doi.org/10.1007/s12098-008-0224-1
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12098-008-0224-1