Pulmonary benign metastasizing leiomyoma

Abstract

Pulmonary benign metastasizing leiomyoma (BML) is a rare disorder affecting women with a history of uterine leiomyoma metastasizing to lung. These lesions present either as a multiple benign synchronous or metachronous nodules. We report a case of 53-year-old postmenopausal women who presented with multiple bilateral pulmonary nodules on a chest X-ray during an evaluation for dyspnea, 11 years after a hysterectomy due to uterine fibroids and excision of abdominal wall tumor. Chest computed tomography (CT) revealed multiple well-defined soft tissue enhancing mass lesions in both lungs, with the largest one in the right lower lobe. She underwent right side bilobectomy by thoracotomy. Pathologically, the resected lesion consisted of benign spindle cells and was diagnosed as smooth muscle tumor of unknown potential which includes BML [1]. Other lung nodules have been meticulously monitored at follow-up, and repeat X-ray after 1 year later showed that these nodules had not increased at all in size and that no new lobe nodules had appeared. She did not receive any adjuvant hormonal therapy because of her postmenopausal status.