Skip to main content

Advertisement

SpringerLink
Log in

Recurrence of a pT2N0cM0 Lower Third Gastric Cancer with No. 6 Lymph Node Micrometastasis after R0 Extended Surgery. Should Adjuvant Therapy be Performed in Conventionally Node-Negative but Micrometastasis-Positive pT2 Gastric Cancer?

  • Case Report
  • Published:
Journal of Gastrointestinal Cancer Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2

References

  1. Marano L, Polom K, Patriti A, Roviello G, Falco G, Stracqualursi A, et al. Surgical management of advanced gastric cancer: an evolving issue. Eur J Surg Oncol. 2016;42:18–27.

    Article  CAS  PubMed  Google Scholar 

  2. Sobin LH, Gospodarowicz MK, Wittekind C. International union against cancer (IUCC) TNM classification of malignant tumours. 7th ed. Oxford: Wiley-Blackwell; 2010.

    Google Scholar 

  3. Jung H, Lee HH, Song KY, Jeon HM, Park CH. Validation of the seventh edition of the American Joint Committee on Cancer TNM staging system for gastric cancer. Cancer. 2011;117:2371–8.

    Article  PubMed  Google Scholar 

  4. Japanese Gastric Cancer Association. Japanese classification of gastric carcinoma: 3rd English edition. Gastric Cancer. 2011;14:101–12.

    Article  Google Scholar 

  5. Arigami T, Uenosono Y, Yanagita S, Nakajo A, Ishigami S, Okumura H, et al. Clinical significance of lymph node micrometastasis in gastric cancer. Ann Surg Oncol. 2013;20:515–21.

    Article  PubMed  Google Scholar 

  6. Griniatsos J, Michail O, Dimitriou N, Karavokyros I. Lymph node, peritoneal and bone marrow micrometastases in gastric cancer: their clinical significance. World J Gastrointest Oncol. 2012;4:16–21.

    Article  PubMed  PubMed Central  Google Scholar 

  7. Waddell T, Verheij M, Allum W, Cunningham D, Cervantes A, Arnold D, et al. Gastric cancer: ESMO-ESSO-ESTRO clinical practice guidelines for diagnosis, treatment and follow-up. Eur J Surg Oncol. 2014;40:584–91.

    Article  CAS  PubMed  Google Scholar 

  8. Japanese Gastric Cancer Association. Japanese gastric cancer treatment guidelines (ver. 3). Gastric Cancer. 2011;14:113–23.

    Article  Google Scholar 

  9. Blouhos K, Boulas KA, Hatzigeorgiadis A. Bursectomy in gastric cancer surgery: surgical technique and operative safety. Updates Surg. 2013;65:95–101.

    Article  PubMed  Google Scholar 

  10. Blouhos K, Boulas KA, Tsalis K, Hatzigeorgiadis A. Right-sided bursectomy as an access plane for aesthetic resection of the posterior leaf of the lesser sac from the head of the pancreas en-block with the No. 6 and 14v lymph nodes in advanced lower-third gastric cancer. Surgery. 2015;158:1742.

    Article  PubMed  Google Scholar 

  11. Sobin LH, Wittekind C. International Union against Cancer. TNM classification of malignant tumours (6th ed). New York: Wiley-Liss; 2002.

    Google Scholar 

  12. Yasuda K, Adachi Y, Shiraishi N, Inomata M, Takeuchi H, Kitano S. Prognostic effect of lymph node micrometastasis in patients with histologically node-negative gastric cancer. Ann Surg Oncol. 2002;9:771–4.

    Article  PubMed  Google Scholar 

  13. Jeuck TL, Wittekind C. Gastric carcinoma: stage migration by immunohistochemically detected lymph node micrometastases. Gastric Cancer. 2015;18:100–8.

    Article  CAS  PubMed  Google Scholar 

  14. Nakajo A, Natsugoe S, Ishigami S, Matsumoto M, Nakashima S, Hokita S, et al. Detection and prediction of micrometastasis in the lymph nodes of patients with pN0 gastric cancer. Ann Surg Oncol. 2001;8:158–62.

    Article  CAS  PubMed  Google Scholar 

  15. Li Y, Du P, Zhou Y, Cheng Q, Chen D, Wang D, et al. Lymph node micrometastases is a poor prognostic factor for patients in pN0 gastric cancer: a meta-analysis of observational studies. J Surg Res. 2014;191:413–22.

    Article  PubMed  Google Scholar 

  16. Lee CM, Cho JM, Jang YJ, Park SS, Park SH, Kim SJ, et al. Should lymph node micrometastasis be considered in node staging for gastric cancer?: the significance of lymph node micrometastasis in gastric cancer. Ann Surg Oncol. 2015;22:765–71.

    Article  PubMed  Google Scholar 

  17. Kim JH, Park SS, Park SH, Kim SJ, Mok YJ, Kim CS, et al. Clinical significance of immunohistochemically-identified lymphatic and/or blood vessel tumor invasion in gastric cancer. J Surg Res. 2010;162:177–83.

    Article  PubMed  Google Scholar 

  18. Zeng YJ, Zhang CD, Dai DQ. Impact of lymph node micrometastasis on gastric carcinoma prognosis: a meta-analysis. World J Gastroenterol. 2015;2:1628–35.

    Article  Google Scholar 

  19. Wu ZY, Li JH, Zhan WH, He YL, Wan J. Effect of lymph node micrometastases on prognosis of gastric carcinoma. World J Gastroenterol. 2007;13:4122–5.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of General Surgery, General Hospital of Drama, Drama, Greece

    Konstantinos Blouhos, Konstantinos A. Boulas, Nikolaos Barettas, Michail Aftzoglou & Anestis Hatzigeorgiadis

  2. D’ Surgical Department, G. Papanikolaou Hospital, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece

    Konstantinos Tsalis

Authors
  1. Konstantinos Blouhos
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Konstantinos A. Boulas
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Konstantinos Tsalis
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Nikolaos Barettas
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Michail Aftzoglou
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Anestis Hatzigeorgiadis
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Konstantinos A. Boulas.

Ethics declarations

Conflict of Interest

The authors declare that they have no conflict of interest.

Informed Consent

Informed consent was obtained from the individual participant of the study.

Funding

None

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Blouhos, K., Boulas, K.A., Tsalis, K. et al. Recurrence of a pT2N0cM0 Lower Third Gastric Cancer with No. 6 Lymph Node Micrometastasis after R0 Extended Surgery. Should Adjuvant Therapy be Performed in Conventionally Node-Negative but Micrometastasis-Positive pT2 Gastric Cancer?. J Gastrointest Canc 48, 89–93 (2017). https://doi.org/10.1007/s12029-016-9811-y

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12029-016-9811-y

Keywords

Search

Navigation