Skip to main content

Advertisement

Log in

Decompressive Craniectomy

  • Review Article
  • Published:
Neurocritical Care Aims and scope Submit manuscript

Abstract

Decompressive Craniectomy (DC) is used to treat elevated intracranial pressure that is unresponsive to conventional treatment modalities. The underlying cause of intracranial hypertension may vary and consequently there is a broad range of literature on the uses of this procedure. Traumatic brain injury (TBI), middle cerebral artery (MCA) infarction, and aneurysmal subarachnoid hemorrhage (SAH) are three conditions for which DC has been predominantly used in the past. Despite an increasing number of reports supportive of DC, the controversy over the suitability of the procedure and criteria for patient selection remains unresolved. Although the majority of published studies is retrospective, the recent publication of several randomized prospective studies prompts a reevaluation of the utility of DC. We review the literature concerning the use of DC in TBI, MCA infarction, and SAH and address the evidence regarding common questions pertaining to the timing of and laterality of the procedure. We conclude that at the time of this review, there still remains insufficient data to support the routine use of DC in TBI, stroke or SAH. There is evidence that early and aggressive use of DC in good-grade patients may improve outcome, but the notion that DC is indicated in these patients is contentious. At this point, the indication for DC should be individualized and its potential implications on long-term outcomes should be comprehensively discussed with the caregivers.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

References

  1. Polin RS, Shaffrey ME, Bogaev CA, et al. Decompressive bifrontal craniectomy in the treatment of severe refractory posttraumatic cerebral edema. Neurosurgery. 1997;41(1):84–92; discussion 92–4.

    Article  PubMed  CAS  Google Scholar 

  2. Fisher CM, Ojemann RG. Bilateral decompressive craniectomy for worsening coma in acute subarachnoid hemorrhage. Observations in support of the procedure. Surg Neurol. 1994;41(1):65–74.

    Article  PubMed  CAS  Google Scholar 

  3. Jaeger M, Soehle M, Meixensberger J. Effects of decompressive craniectomy on brain tissue oxygen in patients with intracranial hypertension. J Neurol Neurosurg Psychiatry. 2003;74(4):513–5.

    Article  PubMed  CAS  Google Scholar 

  4. Stiefel MF, Heuer GG, Smith MJ, et al. Cerebral oxygenation following decompressive hemicraniectomy for the treatment of refractory intracranial hypertension. J Neurosurg. 2004;101(2):241–7.

    PubMed  Google Scholar 

  5. Reithmeier T, Lohr M, Pakos P, Ketter G, Ernestus RI. Relevance of ICP and ptiO(2) for indication and timing of decompressive craniectomy in patients with malignant brain edema. Acta Neurochir (Wien). 2005;147(9):947–52.

    Article  CAS  Google Scholar 

  6. Cho DY, Chen TC, Lee HC. Ultra-early decompressive craniectomy for malignant middle cerebral artery infarction. Surg Neurol. 2003;60(3):227–32; discussion 232–3.

    Article  PubMed  Google Scholar 

  7. Schwab S, Steiner T, Aschoff A, et al. Early hemicraniectomy in patients with complete middle cerebral artery infarction. Stroke. 1998;29(9):1888–93.

    PubMed  CAS  Google Scholar 

  8. Kontopoulos V, Foroglou N, Patsalas J, et al. Decompressive craniectomy for the management of patients with refractory hypertension: should it be reconsidered? Acta Neurochir (Wien). 2002;144(8):791–6.

    Article  CAS  Google Scholar 

  9. Guerra WK, Gaab MR, Dietz H, Mueller JU, Piek J, Fritsch MJ. Surgical decompression for traumatic brain swelling: indications and results. J Neurosurg. 1999;90(2):187–96.

    Article  PubMed  CAS  Google Scholar 

  10. Arnott R, Finger S. Trepanation: history, discovery, theory. 2003: Taylor francis (UK).

  11. Clower WT, Finger S. Discovering trepanation: the contribution of Paul Broca. Neurosurgery. 2001;49(6):1417–25; discussion 1425–6.

    Article  PubMed  CAS  Google Scholar 

  12. Rawlings CE 3rd, Rossitch E Jr. The history of trephination in Africa with a discussion of its current status and continuing practice. Surg Neurol. 1994;41(6):507–13.

    Article  PubMed  Google Scholar 

  13. Al-Rodhan NR, Fox JL. Al-Zahrawi and Arabian neurosurgery, 936–1013 AD. Surg Neurol. 1986;26(1):92–5.

    Article  PubMed  CAS  Google Scholar 

  14. Kocher T. editor. Die Therapie des Hirndruckes. In: Holder A, editor. Hirnerschutterung, Hirndruck und chirurgische Eingriffe bie Hirnkrankheiten. Vienna; 1901. p. 262–266.

  15. Cushing H. The establishment of cerebral hernia as a decompressive measure for innaccessible brain tumors; with the description of intramuscular methods of making the bone defect in temporal and occipital regions. Surg Gynecol Obstet. 1905;1:297–314.

    Google Scholar 

  16. Taylor A, Butt W, Rosenfeld J, et al. A randomized trial of very early decompressive craniectomy in children with traumatic brain injury and sustained intracranial hypertension. Childs Nerv Syst. 2001;17(3):154–62.

    Article  PubMed  CAS  Google Scholar 

  17. Jourdan C, Convert J, Mottolese C, Bachour E, Gharbi S, Artru F. Evaluation of the clinical benefit of decompression hemicraniectomy in intracranial hypertension not controlled by medical treatment. Neurochirurgie. 1993;39(5):304–10.

    PubMed  CAS  Google Scholar 

  18. Chen CC, Cho DY, Tsai SC. Outcome of and prognostic factors for decompressive hemicraniectomy in malignant middle cerebral artery infarction. J Clin Neurosci. 2007;14(4):317–21.

    Article  PubMed  Google Scholar 

  19. Grant GA, Jolley M, Ellenbogen RG, Roberts TS, Gruss JR, Loeser JD. Failure of autologous bone-assisted cranioplasty following decompressive craniectomy in children and adolescents. J Neurosurg. 2004;100(2 Suppl Pediatrics):163–8.

    PubMed  Google Scholar 

  20. Kan P, Amini A, Hansen K, et al. Outcomes after decompressive craniectomy for severe traumatic brain injury in children. J Neurosurg. 2006;105(5 Suppl):337–42.

    PubMed  Google Scholar 

  21. Pillai A, Menon SK, Kumar S, Rajeev K, Kumar A, Panikar D. Decompressive hemicraniectomy in malignant middle cerebral artery infarction: an analysis of long-term outcome and factors in patient selection. J Neurosurg. 2007;106(1):59–65.

    Article  PubMed  Google Scholar 

  22. Ruf B, Heckmann M, Schroth I, et al. Early decompressive craniectomy and duraplasty for refractory intracranial hypertension in children: results of a pilot study. Crit Care. 2003;7(6):R133–8.

    Article  PubMed  Google Scholar 

  23. Liang W, Xiaofeng Y, Weiguo L, et al. Cranioplasty of large cranial defect at an early stage after decompressive craniectomy performed for severe head trauma. J Craniofac Surg. 2007;18(3):526–32.

    Article  PubMed  Google Scholar 

  24. Carvi YNMN, Hollerhage HG. Early combined cranioplasty and programmable shunt in patients with skull bone defects and CSF-circulation disorders. Neurol Res. 2006;28(2):139–44.

    Article  Google Scholar 

  25. Wada Y, Kubo T, Asano T, Senda N, Isono M, Kobayashi H. Fulminant subdural empyema treated with a wide decompressive craniectomy and continuous irrigation—case report. Neurol Med Chir (Tokyo). 2002;42(9):414–6.

    Article  Google Scholar 

  26. Schwab S, Junger E, Spranger M, et al. Craniectomy: an aggressive treatment approach in severe encephalitis. Neurology. 1997;48(2):412–7.

    PubMed  CAS  Google Scholar 

  27. Agrawal D, Hussain N. Decompressive craniectomy in cerebral toxoplasmosis. Eur J Clin Microbiol Infect Dis. 2005;24(11):772–3.

    Article  PubMed  CAS  Google Scholar 

  28. Ausman JI, Rogers C, Sharp HL. Decompressive craniectomy for the encephalopathy of Reye’s syndrome. Surg Neurol. 1976;6(2):97–9.

    PubMed  CAS  Google Scholar 

  29. Mitchell P, Gregson BA, Vindlacheruvu RR, Mendelow AD. Surgical options in ICH including decompressive craniectomy. J Neurol Sci. 2007;261(1–2):89–98.

    Article  PubMed  Google Scholar 

  30. Ziai WC, Port JD, Cowan JA, Garonzik IM, Bhardwaj A, Rigamonti D. Decompressive craniectomy for intractable cerebral edema: experience of a single center. J Neurosurg Anesthesiol. 2003;15(1):25–32.

    Article  PubMed  Google Scholar 

  31. Uhl E, Kreth FW, Elias B, et al. Outcome and prognostic factors of hemicraniectomy for space occupying cerebral infarction. J Neurol Neurosurg Psychiatry. 2004;75(2):270–4.

    PubMed  CAS  Google Scholar 

  32. Carter BS, Ogilvy CS, Candia GJ, Rosas HD, Buonanno F. One-year outcome after decompressive surgery for massive nondominant hemispheric infarction. Neurosurgery. 1997;40(6):1168–75; discussion 1175–6.

    Article  PubMed  CAS  Google Scholar 

  33. Koh MS, Goh KY, Tung MY, Chan C. Is decompressive craniectomy for acute cerebral infarction of any benefit? Surg Neurol. 2000;53(3):225–30.

    Article  PubMed  CAS  Google Scholar 

  34. Kunze E, Meixensberger J, Janka M, Sorensen N, Roosen K. Decompressive craniectomy in patients with uncontrollable intracranial hypertension. Acta Neurochir Suppl. 1998;71:16–8.

    PubMed  CAS  Google Scholar 

  35. Pranesh MB, Dinesh Nayak S, Mathew V, et al. Hemicraniectomy for large middle cerebral artery territory infarction: outcome in 19 patients. J Neurol Neurosurg Psychiatry. 2003;74(6):800–2.

    Article  PubMed  CAS  Google Scholar 

  36. Delashaw JB, Broaddus WC, Kassell NF, et al. Treatment of right hemispheric cerebral infarction by hemicraniectomy. Stroke. 1990;21(6):874–81.

    PubMed  CAS  Google Scholar 

  37. Erban P, Woertgen C, Luerding R, Bogdahn U, Schlachetzki F, Horn M. Long-term outcome after hemicraniectomy for space occupying right hemispheric MCA infarction. Clin Neurol Neurosurg. 2006;108(4):384–7.

    Article  PubMed  Google Scholar 

  38. Holtkamp M, Buchheim K, Unterberg A, et al. Hemicraniectomy in elderly patients with space occupying media infarction: improved survival but poor functional outcome. J Neurol Neurosurg Psychiatry. 2001;70(2):226–8.

    Article  PubMed  CAS  Google Scholar 

  39. Woertgen C, Erban P, Rothoerl RD, Bein T, Horn M, Brawanski A. Quality of life after decompressive craniectomy in patients suffering from supratentorial brain ischemia. Acta Neurochir (Wien). 2004;146(7):691–5.

    Article  CAS  Google Scholar 

  40. Walz B, Zimmermann C, Bottger S, Haberl RL. Prognosis of patients after hemicraniectomy in malignant middle cerebral artery infarction. J Neurol. 2002;249(9):1183–90.

    Article  PubMed  Google Scholar 

  41. Doerfler A, Schwab S, Hoffmann TT, Engelhorn T, Forsting M. Combination of decompressive craniectomy and mild hypothermia ameliorates infarction volume after permanent focal ischemia in rats. Stroke. 2001;32(11):2675–81.

    Article  PubMed  CAS  Google Scholar 

  42. Doerfler A, Forsting M, Reith W, et al. Decompressive craniectomy in a rat model of “malignant” cerebral hemispheric stroke: experimental support for an aggressive therapeutic approach. J Neurosurg. 1996;85(5):853–9.

    PubMed  CAS  Google Scholar 

  43. Forsting M, Reith W, Schabitz WR, et al. Decompressive craniectomy for cerebral infarction. An experimental study in rats. Stroke. 1995;26(2):259–64.

    PubMed  CAS  Google Scholar 

  44. Juttler E, Schwab S, Schmiedek P, et al. Decompressive surgery for the treatment of malignant infarction of the middle cerebral artery (DESTINY): a randomized, controlled trial. Stroke. 2007;38(9):2518–25.

    Article  PubMed  Google Scholar 

  45. Vahedi K, Vicaut E, Mateo J, et al. Sequential-design, multicenter, randomized, controlled trial of early decompressive craniectomy in malignant middle cerebral artery infarction (DECIMAL Trial). Stroke. 2007;38(9):2506–17.

    Article  PubMed  Google Scholar 

  46. Hofmeijer J, Amelink GJ, Algra A, et al. Hemicraniectomy after middle cerebral artery infarction with life-threatening Edema trial (HAMLET). Protocol for a randomised controlled trial of decompressive surgery in space-occupying hemispheric infarction. Trials. 2006;7:29.

    Article  PubMed  Google Scholar 

  47. Vahedi K, Hofmeijer J, Juettler E, et al. Early decompressive surgery in malignant infarction of the middle cerebral artery: a pooled analysis of three randomised controlled trials. Lancet Neurol. 2007;6(3):215–22.

    Article  PubMed  Google Scholar 

  48. Hutchinson P, Timofeev I, Kirkpatrick P. Surgery for brain edema. Neurosurg Focus. 2007;22(5):E14.

    Article  PubMed  Google Scholar 

  49. Mori K, Nakao Y, Yamamoto T, Maeda M. Early external decompressive craniectomy with duroplasty improves functional recovery in patients with massive hemispheric embolic infarction: timing and indication of decompressive surgery for malignant cerebral infarction. Surg Neurol. 2004;62(5):420–9; discussion 429–30.

    PubMed  Google Scholar 

  50. Oppenheim C, Samson Y, Manai R, et al. Prediction of malignant middle cerebral artery infarction by diffusion-weighted imaging. Stroke. 2000;31(9):2175–81.

    PubMed  CAS  Google Scholar 

  51. Gupta R, Connolly ES, Mayer S, Elkind MS. Hemicraniectomy for massive middle cerebral artery territory infarction: a systematic review. Stroke. 2004;35(2):539–43.

    Article  PubMed  Google Scholar 

  52. Brown MM. Surgical decompression of patients with large middle cerebral artery infarcts is effective: not proven. Stroke. 2003;34(9):2305–6.

    Article  PubMed  Google Scholar 

  53. Leonhardt G, Wilhelm H, Doerfler A et al. Clinical outcome and neuropsychological deficits after right decompressive hemicraniectomy in MCA infarction. J Neurol. 2002;249(10):1433–40.

    Article  PubMed  Google Scholar 

  54. Foerch C, Lang JM, Krause J, et al. Functional impairment, disability, and quality of life outcome after decompressive hemicraniectomy in malignant middle cerebral artery infarction. J Neurosurg. 2004;101(2):248–54.

    PubMed  Google Scholar 

  55. Georgiadis D, Schwarz S, Aschoff A, Schwab S. Hemicraniectomy and moderate hypothermia in patients with severe ischemic stroke. Stroke. 2002;33(6):1584–8.

    Article  PubMed  CAS  Google Scholar 

  56. Rabinstein AA, Mueller-Kronast N, Maramattom BV, et al. Factors predicting prognosis after decompressive hemicraniectomy for hemispheric infarction. Neurology. 2006;67(5):891–3.

    Article  PubMed  CAS  Google Scholar 

  57. Sandalcioglu IE, Schoch B, Rauhut F. Hemicraniectomy for large middle cerebral artery territory infarction: do these patients really benefit from this procedure? J Neurol Neurosurg Psychiatry. 2003;74(11):1600; author reply 1600.

    Article  PubMed  CAS  Google Scholar 

  58. Kastrau F, Wolter M, Huber W, Block F. Recovery from aphasia after hemicraniectomy for infarction of the speech-dominant hemisphere. Stroke. 2005;36(4):825–9.

    Article  PubMed  Google Scholar 

  59. Kilincer C, Asil T, Utku U, et al. Factors affecting the outcome of decompressive craniectomy for large hemispheric infarctions: a prospective cohort study. Acta Neurochir (Wien). 2005;147(6):587–94; discussion 594.

    Article  CAS  Google Scholar 

  60. Els T, Oehm E, Voigt S, Klisch J, Hetzel A, Kassubek J. Safety and therapeutical benefit of hemicraniectomy combined with mild hypothermia in comparison with hemicraniectomy alone in patients with malignant ischemic stroke. Cerebrovasc Dis. 2006;21(1–2):79–85.

    Article  PubMed  Google Scholar 

  61. Brain Trauma Foundation. The American Association of Neurological Surgeons. The Joint Section on Neurotrauma and Critical Care.Critical pathway for the treatment of established intracranial hypertension. J Neurotrauma. 2000;17:537–8.

    Google Scholar 

  62. Adamides AA, Winter CD, Lewis PM, Cooper DJ, Kossmann T, Rosenfeld JV. Current controversies in the management of patients with severe traumatic brain injury. ANZ J Surg. 2006;76(3):163–74.

    Article  PubMed  Google Scholar 

  63. Munch E, Horn P, Schurer L, Piepgras A, Paul T, Schmiedek P. Management of severe traumatic brain injury by decompressive craniectomy. Neurosurgery. 2000;47(2):315–22; discussion 322–3.

    Article  PubMed  CAS  Google Scholar 

  64. Gaab MR, Rittierodt M, Lorenz M, Heissler HE. Traumatic brain swelling and operative decompression: a prospective investigation. Acta Neurochir Suppl (Wien). 1990;51:326–8.

    CAS  Google Scholar 

  65. Pompucci A, De Bonis P, Pettorini B, Petrella G, Di Chirico A, Anile C. Decompressive craniectomy for traumatic brain injury: patient age and outcome. J Neurotrauma. 2007;24(7):1182–8.

    Article  PubMed  Google Scholar 

  66. Harrington ML, Bagley RS, Moore MP, Tyler JW. Effect of craniectomy, durotomy, and wound closure on intracranial pressure in healthy cats. Am J Vet Res. 1996;57(11):1659–61.

    PubMed  CAS  Google Scholar 

  67. Albanese J, Leone M, Alliez JR, et al. Decompressive craniectomy for severe traumatic brain injury: Evaluation of the effects at 1 year. Crit Care Med. 2003;31(10):2535–8.

    Article  PubMed  Google Scholar 

  68. Reithmeier T, Speder B, Pakos P, et al. Delayed bilateral craniectomy for treatment of traumatic brain swelling in children: case report and review of the literature. Childs Nerv Syst. 2005;21(3):249–53; discussion 254.

    Article  PubMed  Google Scholar 

  69. Armonda RA, Bell RS, Vo AH, et al. Wartime traumatic cerebral vasospasm: recent review of combat casualties. Neurosurgery. 2006;59(6):1215–25; discussion 1225.

    Article  PubMed  Google Scholar 

  70. Sahuquillo J, Arikan F. Decompressive craniectomy for the treatment of refractory high intracranial pressure in traumatic brain injury. Cochrane Database Syst Rev. 2006;(1):CD003983.

  71. Bullock R, Chesnut RM, Clifton G, et al. Guidelines for the management of severe head injury. Brain Trauma Foundation. Eur J Emerg Med. 1996;3(2):109–27.

    CAS  Google Scholar 

  72. Smith ER, Carter BS, Ogilvy CS. Proposed use of prophylactic decompressive craniectomy in poor-grade aneurysmal subarachnoid hemorrhage patients presenting with associated large sylvian hematomas. Neurosurgery. 2002;51(1):117–24; discussion 124.

    Article  PubMed  Google Scholar 

  73. Schirmer CM, Hoit DA, Malek AM. Decompressive hemicraniectomy for the treatment of intractable intracranial hypertension after aneurysmal subarachnoid hemorrhage. Stroke. 2007;38(3):987–92.

    Article  PubMed  Google Scholar 

  74. D’Ambrosio AL, Sughrue ME, Yorgason JG, et al. Decompressive hemicraniectomy for poor-grade aneurysmal subarachnoid hemorrhage patients with associated intracerebral hemorrhage: clinical outcome and quality of life assessment. Neurosurgery. 2005;56(1):12–9; dicussion 19–20.

    PubMed  Google Scholar 

  75. Buschmann U, Yonekawa Y, Fortunati M, Cesnulis E, Keller E. Decompressive hemicraniectomy in patients with subarachnoid hemorrhage and intractable intracranial hypertension. Acta Neurochir (Wien). 2007;149(1):59–65.

    Article  CAS  Google Scholar 

  76. Strege RJ, Lang EW, Stark AM, et al. Cerebral edema leading to decompressive craniectomy: an assessment of the preceding clinical and neuromonitoring trends. Neurol Res. 2003;25(5):510–5.

    Article  PubMed  Google Scholar 

  77. Aarabi B, Hesdorffer DC, Ahn ES, Aresco C, Scalea TM, Eisenberg HM. Outcome following decompressive craniectomy for malignant swelling due to severe head injury. J Neurosurg. 2006;104(4):469–79.

    Article  PubMed  Google Scholar 

  78. Kilincer C, Simsek O, Hamamcioglu MK, Hicdonmez T, Cobanoglu S. Contralateral subdural effusion after aneurysm surgery and decompressive craniectomy: case report and review of the literature. Clin Neurol Neurosurg. 2005;107(5):412–6.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Adel M. Malek.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Schirmer, C.M., Ackil, A.A. & Malek, A.M. Decompressive Craniectomy. Neurocrit Care 8, 456–470 (2008). https://doi.org/10.1007/s12028-008-9082-y

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12028-008-9082-y

Keywords

Navigation