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Hemangiopericytoma-associated hypoglycemia improved by glucocorticoid therapy: a case report

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Abstract

A 59-year-old man was admitted because of recurrent, severe hypoglycemia. He had multiple metastases from a meningeal hemangiopericytoma, which had been operated on 12 years earlier. The results of laboratory testing at the time of hypoglycemia showed very low serum levels of insulin, C-peptide, and growth hormone, with slightly high levels of insulin-like growth factor-II, and a normal level of insulin-like growth factor-I. The diagnosis of hemangiopericytoma-associated hypoglycemia was proposed. The patient was given corticosteroid therapy, which ameliorated symptoms of hypoglycemia.

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References

  1. S.W. Weiss, J.R. Goldblum (eds.), Enzinger’s and Weiss’s Soft Tissue Tumors (Academic, ST. Louis, 2001)

    Google Scholar 

  2. A.P. Stout, M.R. Murray, Hemangiopericytoma: a vascular tumor featuring Zimmerman’s pericytes. Ann. Surg. 116, 26–33 (1942)

    Article  CAS  PubMed  Google Scholar 

  3. J.W. Howard, P.L. Davis, Retroperitoneal hemangiopericytoma associated with hypoglycemia and masculinization. Delaware Med. J. 31, 29–34 (1959)

    CAS  PubMed  Google Scholar 

  4. K. Pavelić, S. Spaventi, V. Gluncić, A. Matejcić, D. Pavicić, N. Karapandza, Z. Kusić, J. Lukac, C. Dohoczky, T. Cabrijan, J. Pavelić, The expression, role of insulin-like growth factor II in malignant hemangiopericytomas. J. Mol. Med. 77, 865–869 (1999)

    Article  PubMed  Google Scholar 

  5. J.W. de Groot, B. Rikhof, J. van Doorn, H.J. Bilo, M.A. Alleman, A.H. Honkoop, W.T. van der Graaf, Non-islet cell tumour induced hypoglycemia: a review of the literature including two new cases. Endocr. Relat. Cancer 14, 979–993 (2007)

    Article  PubMed  Google Scholar 

  6. N. Hizuka, I. Fukuda, K. Takano, Y. Okubo, K. Asakawa-Yasumoto, K. Demura, Serum insulin-like growth factor in 44 patients with non-islet cell tumor hypoglycemia. Endocr. J. 45(Suppl), S61–S65 (1998)

    Article  CAS  PubMed  Google Scholar 

  7. W.H. Daughaday, B. Trivedi, R.C. Baxter, Abnormal serum IGF-II transport in non-islet cell tumor hypoglycemia results from abnormalities of both IGF binding protein-3 and acid labile subunit and leads to elevation of serum free IGF-II. Endocrine 3, 425–428 (1995)

    Article  CAS  Google Scholar 

  8. I. Fukuda, N. Hizuka, Y. Ishikawa, K. Yasumoto, Y. Murakami, A. Sata, J. Morita, M. Kurimoto, Y. Okubo, K. Takano, Clinical features of insulin-like growth factor-II producing non-islet-cell tumor hypoglycemia. Growth Horm. IGF Res. 16, 211–216 (2006)

    Article  CAS  PubMed  Google Scholar 

  9. J.M. Guettier, P. Gorden, Hypoglycemia. Endocrinol. Metab. Clin. North Am. 35(753–766), viii–ix (2006)

    Google Scholar 

  10. F.J. Service, Hypoglycemic disorders. N. Engl. J. Med. 332, 1144–1152 (1995)

    Article  CAS  PubMed  Google Scholar 

  11. J.D. Teale, G. Wark, The effectiveness of different treatment options for non-islet cell tumour hypoglycaemia. Clin. Endocrinol. (Oxf) 60, 457–460 (2004)

    Article  CAS  Google Scholar 

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Correspondence to İnan Anaforoğlu.

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Anaforoğlu, İ., Şimşek, A., Turan, T. et al. Hemangiopericytoma-associated hypoglycemia improved by glucocorticoid therapy: a case report. Endocr 36, 151–154 (2009). https://doi.org/10.1007/s12020-009-9197-8

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  • DOI: https://doi.org/10.1007/s12020-009-9197-8

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