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Endoscopic Treatment of Early-Stage Esophageal Cancer

  • Gastrointestinal Cancers (J Meyer, Section Editor)
  • Published:
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Abstract

Purpose of Review

Esophageal cancer is a leading cause of global cancer-related mortality. Here, we discuss the major endoscopic treatment modalities for management of early esophageal cancer (EEC).

Recent Findings

Advances in endoscopic imaging and therapy have shifted the paradigm of managing early esophageal cancers. Though esophagectomy remains the preferred management for advanced cancers, guidelines now recommend endoscopic resection followed by ablative therapy for early (Tis and T1a) cancers. Available data suggests endoscopic treatment is comparable to surgery with regard to overall and cancer-specific survival with lower procedural morbidity and mortality.

Summary

Endoscopic modalities are emerging as frontline treatment options for patients with early esophageal cancers. Accurate clinical staging with assessment of disease extent, tumor grade, and risk of nodal metastases is crucial when determining eligibility for endoscopic management of EEC. High-quality routine surveillance endoscopy is critical in patients who have undergone resection and/or ablation.

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Authors and Affiliations

  1. Department of Internal Medicine, University of Iowa Hospital and Clinics, Iowa City, USA

    Mariam Naveed

  2. Department of Internal Medicine, UT Southwestern Medical Center, Dallas, USA

    Nisa Kubiliun

  3. Division of Digestive and Liver Diseases, University of Texas Southwestern, 1801 Inwood Road, Suite 6.102, Dallas, TX, 75390-9083, USA

    Nisa Kubiliun

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  1. Mariam Naveed
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Naveed, M., Kubiliun, N. Endoscopic Treatment of Early-Stage Esophageal Cancer. Curr Oncol Rep 20, 71 (2018). https://doi.org/10.1007/s11912-018-0713-y

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