Skip to main content

Advertisement

Log in

Understanding the Epidemic of Heart Failure: Past, Present, and Future

  • Epidemiology of Heart Failure (CSP Lam, Section Editor)
  • Published:
Current Heart Failure Reports Aims and scope Submit manuscript

Abstract

Heart failure (HF) is a major public health problem affecting more than five million Americans and more than 23 million patients worldwide. The epidemiology of HF is evolving. Data suggests that the incidence of HF peaked in the mid-1990s and has since declined. Survival after HF diagnosis has improved, leading to an increase in prevalence. The case mix is also changing, as a rising proportion of patients with HF have preserved ejection fraction and multimorbidity is increasingly common. After diagnosis, HF can have a profound associated morbidity. Hospitalizations in HF remain both frequent and costly, though they may be declining as a result of preventive efforts. The need for skilled nursing facility care in HF has risen. The role of palliative medicine in the care of patients with advanced HF is evolving as we learn how to best care for this population with a large symptom burden.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of Major Importance

  1. Go AS, Mozaffarian D, Roger VL, Benjamin EJ, Berry JD, Blaha MJ, et al. Executive summary: heart disease and stroke statistics—2014 update: a report from the American Heart Association. Circulation. 2014;129:399–410.

    Article  PubMed  Google Scholar 

  2. Heidenreich PA, Albert NM, Allen LA, Bluemke DA, Butler J, Fonarow GC, et al. Forecasting the impact of heart failure in the United States: a policy statement from the American Heart Association. Circ Heart Fail. 2013;6:606–19. This paper estimates the future costs and epidemiology of heart failure in the United States, which is useful for understanding the epidemic of heart failure and anticipating future population needs.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  3. Yancy CW, Jessup M, Bozkurt B, Butler J, Casey Jr DE, Drazner MH, et al. 2013 ACCF/AHA guideline for the management of heart failure: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on practice guidelines. Circulation. 2013;128:1810–52. These are the most recent U.S. guidelines for the care of patients with heart failure and include several important changes in management compared with earlier versions.

    Article  PubMed  Google Scholar 

  4. McKee PA, Castelli WP, McNamara PM, Kannel WB. The natural history of congestive heart failure: the Framingham study. New Engl J Med. 1971;285:1441–6.

    Article  CAS  PubMed  Google Scholar 

  5. Eriksson H, Caidahl K, Larsson B, Ohlson LO, Welin L, Wilhelmsen L, et al. Cardiac and pulmonary causes of dyspnoea—validation of a scoring test for clinical-epidemiological use: the Study of Men Born in 1913. Eur Heart J. 1987;8:1007–14.

    CAS  PubMed  Google Scholar 

  6. Carlson KJ, Lee DC, Goroll AH, Leahy M, Johnson RA. An analysis of physicians’ reasons for prescribing long-term digitalis therapy in outpatients. J Chron Dis. 1985;38:733–9.

    Article  CAS  PubMed  Google Scholar 

  7. Swedberg K, Cleland J, Dargie H, Drexler H, Follath F, Komajda M, et al. Guidelines for the diagnosis and treatment of chronic heart failure: executive summary (update 2005): the Task Force for the Diagnosis and Treatment of Chronic Heart Failure of the European Society of Cardiology. Eur Heart J. 2005;26:1115–40.

    Article  PubMed  CAS  Google Scholar 

  8. Di Bari M, Pozzi C, Cavallini MC, Innocenti F, Baldereschi G, De Alfieri W, et al. The diagnosis of heart failure in the community. Comparative validation of four sets of criteria in unselected older adults: the ICARe Dicomano Study. J Am Coll Cardiol. 2004;44:1601–8.

    Article  PubMed  Google Scholar 

  9. Psaty BM, Boineau R, Kuller LH, Luepker RV. The potential costs of upcoding for heart failure in the United States. Am J Cardiol. 1999;84:108–9. A9.

    Article  CAS  PubMed  Google Scholar 

  10. Goldberg RJ, Spencer FA, Farmer C, Meyer TE, Pezzella S. Incidence and hospital death rates associated with heart failure: a community-wide perspective. Am J Med. 2005;118:728–34.

    Article  PubMed  Google Scholar 

  11. Bleumink GS, Knetsch AM, Sturkenboom MC, Straus SM, Hofman A, Deckers JW, et al. Quantifying the heart failure epidemic: prevalence, incidence rate, lifetime risk and prognosis of heart failure. The Rotterdam Study. Eur Heart J. 2004;25:1614–9.

    Article  PubMed  Google Scholar 

  12. Croft JB, Giles WH, Pollard RA, Casper ML, Anda RF, Livengood JR. National trends in the initial hospitalization for heart failure. J Am Geriatr Soc. 1997;45:270–5.

    CAS  PubMed  Google Scholar 

  13. Curtis LH, Whellan DJ, Hammill BG, Hernandez AF, Anstrom KJ, Shea AM, et al. Incidence and prevalence of heart failure in elderly persons, 1994–2003. Arch Intern Med. 2008;168:418–24.

    Article  PubMed  Google Scholar 

  14. Bibbins-Domingo K, Pletcher MJ, Lin F, Vittinghoff E, Gardin JM, Arynchyn A, et al. Racial differences in incident heart failure among young adults. New Engl J Med. 2009;360:1179–90.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  15. McCullough PA, Philbin EF, Spertus JA, Kaatz S, Sandberg KR, Weaver WD. Confirmation of a heart failure epidemic: findings from the Resource Utilization Among Congestive Heart Failure (REACH) study. J Am Coll Cardiol. 2002;39:60–9.

    Article  PubMed  Google Scholar 

  16. Bahrami H, Kronmal R, Bluemke DA, Olson J, Shea S, Liu K, et al. Differences in the incidence of congestive heart failure by ethnicity: the multi-ethnic study of atherosclerosis. Arch Intern Med. 2008;168:2138–45.

    Article  PubMed Central  PubMed  Google Scholar 

  17. Loehr LR, Rosamond WD, Chang PP, Folsom AR, Chambless LE. Heart failure incidence and survival (from the Atherosclerosis Risk in Communities study). Am J Cardiol. 2008;101:1016–22.

    Article  PubMed  Google Scholar 

  18. Barasa A, Schaufelberger M, Lappas G, Swedberg K, Dellborg M, Rosengren A. Heart failure in young adults: 20-year trends in hospitalization, aetiology, and case fatality in Sweden. Eur Heart J. 2014;35:25–32.

    Article  PubMed Central  PubMed  Google Scholar 

  19. Levy D, Kenchaiah S, Larson MG, Benjamin EJ, Kupka MJ, Ho KK, et al. Long-term trends in the incidence of and survival with heart failure. New Engl J Med. 2002;347:1397–402.

    Article  PubMed  Google Scholar 

  20. Roger VL, Weston SA, Redfield MM, Hellermann-Homan JP, Killian J, Yawn BP, et al. Trends in heart failure incidence and survival in a community-based population. JAMA. 2004;292:344–50.

    Article  CAS  PubMed  Google Scholar 

  21. Stewart S, MacIntyre K, MacLeod MM, Bailey AE, Capewell S, McMurray JJ. Trends in hospitalization for heart failure in Scotland, 1990–1996. An epidemic that has reached its peak? Eur Heart J. 2001;22:209–17.

    Article  CAS  PubMed  Google Scholar 

  22. Teng TH, Finn J, Hobbs M, Hung J. Heart failure: incidence, case fatality, and hospitalization rates in Western Australia between 1990 and 2005. Circ Heart Fail. 2010;3:236–43.

    Article  PubMed  Google Scholar 

  23. Yeung DF, Boom NK, Guo H, Lee DS, Schultz SE, Tu JV. Trends in the incidence and outcomes of heart failure in Ontario, Canada: 1997 to 2007. Can Med Assoc J. 2012;184:E765–73.

    Article  Google Scholar 

  24. Lloyd-Jones DM, Larson MG, Leip EP, Beiser A, D’Agostino RB, Kannel WB, et al. Lifetime risk for developing congestive heart failure: the Framingham Heart Study. Circulation. 2002;106:3068–72.

    Article  PubMed  Google Scholar 

  25. Huffman MD, Berry JD, Ning H, Dyer AR, Garside DB, Cai X, et al. Lifetime risk for heart failure among white and black Americans: cardiovascular lifetime risk pooling project. J Am Coll Cardiol. 2013;61:1510–7. This is the first paper to estimate lifetime risk of heart failure in both black and white men and women and highlights important racial differences in risk in men.

    Article  PubMed Central  PubMed  Google Scholar 

  26. Bursi F, Weston SA, Redfield MM, Jacobsen SJ, Pakhomov S, Nkomo VT, et al. Systolic and diastolic heart failure in the community. JAMA. 2006;296:2209–16.

    Article  CAS  PubMed  Google Scholar 

  27. Cleland JG, Tendera M, Adamus J, Freemantle N, Polonski L, Taylor J. The perindopril in elderly people with chronic heart failure (PEP-CHF) study. Eur Heart J. 2006;27:2338–45.

    Article  CAS  PubMed  Google Scholar 

  28. Owan TE, Hodge DO, Herges RM, Jacobsen SJ, Roger VL, Redfield MM. Trends in prevalence and outcome of heart failure with preserved ejection fraction. New Engl J Med. 2006;355:251–9.

    Article  CAS  PubMed  Google Scholar 

  29. Redfield MM, Jacobsen SJ, Burnett Jr JC, Mahoney DW, Bailey KR, Rodeheffer RJ. Burden of systolic and diastolic ventricular dysfunction in the community: appreciating the scope of the heart failure epidemic. JAMA. 2003;289:194–202.

    Article  PubMed  Google Scholar 

  30. Bhatia RS, Tu JV, Lee DS, Austin PC, Fang J, Haouzi A, et al. Outcome of heart failure with preserved ejection fraction in a population-based study. New Engl J Med. 2006;355:260–9.

    Article  CAS  PubMed  Google Scholar 

  31. Fonarow GC, Stough WG, Abraham WT, Albert NM, Gheorghiade M, Greenberg BH, et al. Characteristics, treatments, and outcomes of patients with preserved systolic function hospitalized for heart failure: a report from the OPTIMIZE-HF Registry. J Am Coll Cardiol. 2007;50:768–77.

    Article  PubMed  Google Scholar 

  32. Kitzman DW, Little WC, Brubaker PH, Anderson RT, Hundley WG, Marburger CT, et al. Pathophysiological characterization of isolated diastolic heart failure in comparison to systolic heart failure. JAMA. 2002;288:2144–50.

    Article  PubMed  Google Scholar 

  33. Massie BM, Carson PE, McMurray JJ, Komajda M, McKelvie R, Zile MR, et al. Irbesartan in patients with heart failure and preserved ejection fraction. N Engl J Med. 2008;359:2456–67.

    Article  CAS  PubMed  Google Scholar 

  34. Yusuf S, Pfeffer MA, Swedberg K, Granger CB, Held P, McMurray JJ, et al. Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: the CHARM-Preserved Trial. Lancet. 2003;362:777–81.

    Article  CAS  PubMed  Google Scholar 

  35. Borlaug BA, Redfield MM. Diastolic and systolic heart failure are distinct phenotypes within the heart failure spectrum. Circulation. 2011;123:2006–13. discussion 2014.

    Article  PubMed Central  PubMed  Google Scholar 

  36. West R, Liang L, Fonarow GC, Kociol R, Mills RM, O’Connor CM, et al. Characterization of heart failure patients with preserved ejection fraction: a comparison between ADHERE-US registry and ADHERE-International registry. Eur J Heart Fail. 2011;13:945–52.

    Article  PubMed Central  PubMed  Google Scholar 

  37. Dunlay SM, Roger VL, Weston SA, Jiang R, Redfield MM. Longitudinal changes in ejection fraction in heart failure patients with preserved and reduced ejection fraction. Circ Heart Fail. 2012;5:720–6.

    Article  PubMed Central  PubMed  Google Scholar 

  38. Lam CS, Donal E, Kraigher-Krainer E, Vasan RS. Epidemiology and clinical course of heart failure with preserved ejection fraction. Eur J Heart Fail. 2011;13:18–28.

    Article  PubMed Central  PubMed  Google Scholar 

  39. Avery CL, Loehr LR, Baggett C, Chang PP, Kucharska-Newton AM, Matsushita K, et al. The population burden of heart failure attributable to modifiable risk factors: the ARIC (Atherosclerosis Risk in Communities) study. J Am Coll Cardiol. 2012;60:1640–6. This analysis including nearly 15,000 patients participating in the ARIC study demonstrates that even a modest reduction in the prevalence of risk factors for heart failure could translate into a large decrease in the annual incidence of heart failure.

    Article  PubMed  Google Scholar 

  40. Dunlay SM, Weston SA, Jacobsen SJ, Roger VL. Risk factors for heart failure: a population-based case-control study. Am J Med. 2009;122:1023–8.

    Article  PubMed Central  PubMed  Google Scholar 

  41. Folsom AR, Yamagishi K, Hozawa A, Chambless LE. Absolute and attributable risks of heart failure incidence in relation to optimal risk factors. Circ Heart Fail. 2009;2:11–7.

    Article  PubMed Central  PubMed  Google Scholar 

  42. Gottdiener JS, Arnold AM, Aurigemma GP, Polak JF, Tracy RP, Kitzman DW, et al. Predictors of congestive heart failure in the elderly: the Cardiovascular Health Study. J Am Coll Cardiol. 2000;35:1628–37.

    Article  CAS  PubMed  Google Scholar 

  43. Levy D, Larson MG, Vasan RS, Kannel WB, Ho KK. The progression from hypertension to congestive heart failure. JAMA. 1996;275:1557–62.

    Article  CAS  PubMed  Google Scholar 

  44. Loehr LR, Rosamond WD, Poole C, McNeill AM, Chang PP, Deswal A, et al. The potentially modifiable burden of incident heart failure due to obesity: the Atherosclerosis Risk in Communities study. Am J Epidemiol. 2010;172:781–9.

    Article  PubMed Central  PubMed  Google Scholar 

  45. He J, Ogden LG, Bazzano LA, Vupputuri S, Loria C, Whelton PK. Risk factors for congestive heart failure in US men and women: NHANES I epidemiologic follow-up study. Arch Intern Med. 2001;161:996–1002.

    Article  CAS  PubMed  Google Scholar 

  46. Barker WH, Mullooly JP, Getchell W. Changing incidence and survival for heart failure in a well-defined older population, 1970–1974 and 1990–1994. Circulation. 2006;113:799–805.

    Article  PubMed  Google Scholar 

  47. Flegal KM, Carroll MD, Ogden CL, Johnson CL. Prevalence and trends in obesity among US adults, 1999–2000. JAMA. 2002;288:1723–7.

    Article  PubMed  Google Scholar 

  48. Gregg EW, Cheng YJ, Cadwell BL, Imperatore G, Williams DE, Flegal KM, et al. Secular trends in cardiovascular disease risk factors according to body mass index in US adults. JAMA. 2005;293:1868–74.

    Article  CAS  PubMed  Google Scholar 

  49. Dunlay SM, Redfield MM, Weston SA, Therneau TM, Hall Long K, Shah ND, et al. Hospitalizations after heart failure diagnosis a community perspective. J Am Coll Cardiol. 2009;54:1695–702.

    Article  PubMed Central  PubMed  Google Scholar 

  50. Henkel DM, Redfield MM, Weston SA, Gerber Y, Roger VL. Death in heart failure: a community perspective. Circ Heart Fail. 2008;1:91–7.

    Article  PubMed Central  PubMed  Google Scholar 

  51. Wong CY, Chaudhry SI, Desai MM, Krumholz HM. Trends in comorbidity, disability, and polypharmacy in heart failure. Am J Med. 2011;124:136–43.

    Article  PubMed Central  PubMed  Google Scholar 

  52. Saczynski JS, Go AS, Magid DJ, Smith DH, McManus DD, Allen L, et al. Patterns of comorbidity in older adults with heart failure: the Cardiovascular Research Network PRESERVE study. J Am Geriatr Soc. 2013;61:26–33.

    Article  PubMed Central  PubMed  Google Scholar 

  53. Fortin M, Stewart M, Poitras ME, Almirall J, Maddocks H. A systematic review of prevalence studies on multimorbidity: toward a more uniform methodology. Ann Fam Med. 2012;10:142–51.

    Article  PubMed Central  PubMed  Google Scholar 

  54. Chen J, Normand SL, Wang Y, Krumholz HM. National and regional trends in heart failure hospitalization and mortality rates for Medicare beneficiaries, 1998–2008. JAMA. 2011;306:1669–78.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  55. Sutcliffe S, Phillips C, Watson D, Davidson C. Trends in heart failure mortality in England and Wales since 1950. Eur J Intern Med. 2007;18:576–80.

    Article  PubMed  Google Scholar 

  56. Curtis LH, Greiner MA, Hammill BG, Kramer JM, Whellan DJ, Schulman KA, et al. Early and long-term outcomes of heart failure in elderly persons, 2001–2005. Arch Intern Med. 2008;168:2481–8.

    Article  PubMed Central  PubMed  Google Scholar 

  57. Chen J, Dharmarajan K, Wang Y, Krumholz HM. National trends in heart failure hospital stay rates, 2001 to 2009. J Am Coll Cardiol. 2013;61:1078–88. Highlights the fact that while in-hospital mortality and length of stay have improved for some groups of patients hospitalized with heart failure, gains have not been seen in younger patients and blacks.

    Article  PubMed Central  PubMed  Google Scholar 

  58. Bueno H, Ross JS, Wang Y, Chen J, Vidan MT, Normand SL, et al. Trends in length of stay and short-term outcomes among Medicare patients hospitalized for heart failure, 1993–2006. JAMA. 2010;303:2141–7.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  59. O’Connor CM, Miller AB, Blair JE, Konstam MA, Wedge P, Bahit MC, et al. Causes of death and rehospitalization in patients hospitalized with worsening heart failure and reduced left ventricular ejection fraction: results from Efficacy of Vasopressin Antagonism in Heart Failure Outcome Study with Tolvaptan (EVEREST) program. Am Heart J. 2010;159:841–49 e1.

    Article  PubMed  CAS  Google Scholar 

  60. Remme WJ, Cleland JG, Erhardt L, Spark P, Torp-Pedersen C, Metra M, et al. Effect of carvedilol and metoprolol on the mode of death in patients with heart failure. Eur J Heart Fail. 2007;9:1128–35.

    Article  CAS  PubMed  Google Scholar 

  61. Jencks SF, Williams MV, Coleman EA. Rehospitalizations among patients in the Medicare fee-for-service program. New Engl J Med. 2009;360:1418–28.

    Article  CAS  PubMed  Google Scholar 

  62. Chun S, Tu JV, Wijeysundera HC, Austin PC, Wang X, Levy D, et al. Lifetime analysis of hospitalizations and survival of patients newly admitted with heart failure. Circ Heart Fail. 2012;5:414–21.

    Article  PubMed  Google Scholar 

  63. Blecker S, Paul M, Taksler G, Ogedegbe G, Katz S. Heart failure-associated hospitalizations in the United States. J Am Coll Cardiol. 2013;61:1259–67.

    Article  PubMed  Google Scholar 

  64. Dunlay SM, Shah ND, Shi Q, Morlan B, VanHouten H, Long KH, et al. Lifetime costs of medical care after heart failure diagnosis. Circ Cardiovasc Qual Outcomes. 2011;4:68–75.

    Article  PubMed Central  PubMed  Google Scholar 

  65. Hospital Readmissions Reduction Program. Affordable Care Act, 2012.

  66. Setoguchi S, Stevenson LW. Hospitalizations in patients with heart failure: who and why. J Am Coll Cardiol. 2009;54:1703–5.

    Article  PubMed  Google Scholar 

  67. Ather S, Chan W, Bozkurt B, Aguilar D, Ramasubbu K, Zachariah AA, et al. Impact of noncardiac comorbidities on morbidity and mortality in a predominantly male population with heart failure and preserved versus reduced ejection fraction. J Am Coll Cardiol. 2012;59:998–1005.

    Article  PubMed  Google Scholar 

  68. Ezekowitz JA, Kaul P, Bakal JA, Quan H, McAlister FA. Trends in heart failure care: has the incident diagnosis of heart failure shifted from the hospital to the emergency department and outpatient clinics? Eur J Heart Fail. 2011;13:142–7.

    Article  PubMed  Google Scholar 

  69. Schaufelberger M, Swedberg K, Koster M, Rosen M, Rosengren A. Decreasing one-year mortality and hospitalization rates for heart failure in Sweden; data from the Swedish Hospital Discharge Registry 1988 to 2000. Eur Heart J. 2004;25:300–7.

    Article  PubMed  Google Scholar 

  70. Mosterd A, Reitsma JB, Grobbee DE. Angiotensin converting enzyme inhibition and hospitalisation rates for heart failure in the Netherlands, 1980 to 1999: the end of an epidemic? Heart. 2002;87:75–6.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  71. Wasywich CA, Gamble GD, Whalley GA, Doughty RN. Understanding changing patterns of survival and hospitalization for heart failure over two decades in New Zealand: utility of ‘days alive and out of hospital’ from epidemiological data. Eur J Heart Fail. 2010;12:462–8.

    Article  PubMed  Google Scholar 

  72. Jhund PS, Macintyre K, Simpson CR, Lewsey JD, Stewart S, Redpath A, et al. Long-term trends in first hospitalization for heart failure and subsequent survival between 1986 and 2003: a population study of 5.1 million people. Circulation. 2009;119:515–23.

    Article  PubMed  Google Scholar 

  73. Ross JS, Chen J, Lin Z, Bueno H, Curtis JP, Keenan PS, et al. Recent national trends in readmission rates after heart failure hospitalization. Circ Heart Fail. 2010;3:97–103.

    Article  PubMed Central  PubMed  Google Scholar 

  74. Gerhardt G, Yemane A, Hickman P, Olschlaegger A, Rollins E, Brennan N. Data show reduction in medicare hospital readmission rates in 2012. Medicare and Medicaid Research Review 2013;3.

  75. Fang J, Mensah GA, Croft JB, Keenan NL. Heart failure-related hospitalization in the U.S., 1979 to 2004. J Am Coll Cardiol. 2008;52:428–34.

    Article  PubMed  Google Scholar 

  76. Allen LA, Hernandez AF, Peterson ED, Curtis LH, Dai D, Masoudi FA, et al. Discharge to a skilled nursing facility and subsequent clinical outcomes among older patients hospitalized for heart failure. Circ Heart Fail. 2011;4:293–300.

    Article  PubMed Central  PubMed  Google Scholar 

  77. Chen J, Ross JS, Carlson MD, Lin Z, Normand SL, Bernheim SM, et al. Skilled nursing facility referral and hospital readmission rates after heart failure or myocardial infarction. Am J Med. 2012;125:100 e1–9.

    Google Scholar 

  78. Stewart GC, Stevenson LW. Keeping left ventricular assist device acceleration on track. Circulation. 2011;123:1559–68. discussion 1568.

    Article  PubMed  Google Scholar 

  79. Rose EA, Gelijns AC, Moskowitz AJ, Heitjan DF, Stevenson LW, Dembitsky W, et al. Long-term use of a left ventricular assist device for end-stage heart failure. New Engl J Med. 2001;345:1435–43.

    Article  CAS  PubMed  Google Scholar 

  80. Bekelman DB, Rumsfeld JS, Havranek EP, Yamashita TE, Hutt E, Gottlieb SH, et al. Symptom burden, depression, and spiritual well-being: a comparison of heart failure and advanced cancer patients. J Gen Intern Med. 2009;24:592–8.

    Article  PubMed Central  PubMed  Google Scholar 

  81. Setoguchi S, Glynn RJ, Stedman M, Flavell CM, Levin R, Stevenson LW. Hospice, opiates, and acute care service use among the elderly before death from heart failure or cancer. Am Heart J. 2010;160:139–44.

    Article  PubMed Central  PubMed  Google Scholar 

  82. Unroe KT, Greiner MA, Hernandez AF, Whellan DJ, Kaul P, Schulman KA, et al. Resource use in the last 6 months of life among medicare beneficiaries with heart failure, 2000–2007. Arch Intern Med. 2011;171:196–203.

    Article  PubMed  Google Scholar 

  83. Unroe KT, Greiner MA, Johnson KS, Curtis LH, Setoguchi S. Racial differences in hospice use and patterns of care after enrollment in hospice among Medicare beneficiaries with heart failure. Am Heart J. 2012;163:987–93 e3.

    Article  PubMed  Google Scholar 

  84. Dunlay SM, Swetz KM, Redfield MM, Mueller PS, Roger VL. Resuscitation preferences in community patients with heart failure. Circ Cardiovasc Qual Outcomes. 2014;7:353–9.

    Article  PubMed  Google Scholar 

  85. Meier DE. Increased access to palliative care and hospice services: opportunities to improve value in health care. Milbank Q. 2011;89:343–80.

    Article  PubMed Central  PubMed  Google Scholar 

  86. Allen LA, Stevenson LW, Grady KL, Goldstein NE, Matlock DD, Arnold RM, et al. Decision making in advanced heart failure: a scientific statement from the American Heart Association. Circulation. 2012;125:1928–52. This scientific statement from the American Heart Association discusses the importance of shared decision making in patients with advanced heart failure and provides detailed guidance for clinicians on how and when to discuss goals of care and end-of-life preferences with patients with advanced heart failure.

    Article  PubMed Central  PubMed  Google Scholar 

  87. Jaarsma T, Beattie JM, Ryder M, Rutten FH, McDonagh T, Mohacsi P, et al. Palliative care in heart failure: a position statement from the palliative care workshop of the Heart Failure Association of the European Society of Cardiology. Eur J Heart Fail. 2009;11:433–43.

    Article  PubMed  Google Scholar 

  88. Schocken DD, Arrieta MI, Leaverton PE, Ross EA. Prevalence and mortality rate of congestive heart failure in the United States. J Am Coll Cardiol. 1992;20:301–6.

    Article  CAS  PubMed  Google Scholar 

  89. Cowie MR, Wood DA, Coats AJ, Thompson SG, Poole-Wilson PA, Suresh V, et al. Incidence and aetiology of heart failure; a population-based study. Eur Heart J. 1999;20:421–8.

    Article  CAS  PubMed  Google Scholar 

  90. Cowie MR, Wood DA, Coats AJ, Thompson SG, Suresh V, Poole-Wilson PA, et al. Survival of patients with a new diagnosis of heart failure: a population based study. Heart. 2000;83:505–10.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  91. Davies M, Hobbs F, Davis R, Kenkre J, Roalfe AK, Hare R, et al. Prevalence of left-ventricular systolic dysfunction and heart failure in the Echocardiographic Heart of England Screening study: a population based study. Lancet. 2001;358:439–44.

    Article  CAS  PubMed  Google Scholar 

  92. Nielsen OW, Hilden J, Larsen CT, Hansen JF. Cross sectional study estimating prevalence of heart failure and left ventricular systolic dysfunction in community patients at risk. Heart. 2001;86:172–8.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  93. Remes J, Reunanen A, Aromaa A, Pyorala K. Incidence of heart failure in eastern Finland: a population-based surveillance study. Eur Heart J. 1992;13:588–93.

    CAS  PubMed  Google Scholar 

  94. Lee DS, Gona P, Vasan RS, Larson MG, Benjamin EJ, Wang TJ, et al. Relation of disease pathogenesis and risk factors to heart failure with preserved or reduced ejection fraction: insights from the Framingham Heart Study of the National Heart, Lung, and Blood Institute. Circulation. 2009;119:3070–7.

    Article  PubMed Central  PubMed  Google Scholar 

  95. Ho JE, Lyass A, Lee DS, Vasan RS, Kannel WB, Larson MG, et al. Predictors of new-onset heart failure: differences in preserved versus reduced ejection fraction. Circ Heart Fail. 2013;6:279–86.

    Article  PubMed Central  PubMed  Google Scholar 

  96. Devereux RB, Roman MJ, Liu JE, Welty TK, Lee ET, Rodeheffer R, et al. Congestive heart failure despite normal left ventricular systolic function in a population-based sample: the Strong Heart Study. Am J Cardiol. 2000;86:1090–6.

    Article  CAS  PubMed  Google Scholar 

  97. Gottdiener JS, McClelland RL, Marshall R, Shemanski L, Furberg CD, Kitzman DW, et al. Outcome of congestive heart failure in elderly persons: influence of left ventricular systolic function. The Cardiovascular Health Study. Ann Intern Med. 2002;137:631–9.

    Article  PubMed  Google Scholar 

  98. Yancy CW, Lopatin M, Stevenson LW, De Marco T, Fonarow GC. Clinical presentation, management, and in-hospital outcomes of patients admitted with acute decompensated heart failure with preserved systolic function: a report from the Acute Decompensated Heart Failure National Registry (ADHERE) Database. J Am Coll Cardiol. 2006;47:76–84.

    Article  PubMed  Google Scholar 

  99. Philbin EF, Rocco Jr TA, Lindenmuth NW, Ulrich K, Jenkins PL. Systolic versus diastolic heart failure in community practice: clinical features, outcomes, and the use of angiotensin-converting enzyme inhibitors. Am J Med. 2000;109:605–13.

    Article  CAS  PubMed  Google Scholar 

  100. Brouwers FP, de Boer RA, van der Harst P, Voors AA, Gansevoort RT, Bakker SJ, et al. Incidence and epidemiology of new onset heart failure with preserved vs. reduced ejection fraction in a community-based cohort: 11-year follow-up of PREVEND. Eur Heart J. 2013;34:1424–31.

    Article  CAS  PubMed  Google Scholar 

  101. Gurwitz JH, Magid DJ, Smith DH, Goldberg RJ, McManus DD, Allen LA, et al. Contemporary prevalence and correlates of incident heart failure with preserved ejection fraction. Am J Med. 2013;126:393–400.

    Article  PubMed Central  PubMed  Google Scholar 

  102. Gustafsson F, Torp-Pedersen C, Brendorp B, Seibaek M, Burchardt H, Kober L. Long-term survival in patients hospitalized with congestive heart failure: relation to preserved and reduced left ventricular systolic function. Eur Heart J. 2003;24:863–70.

    Article  PubMed  Google Scholar 

  103. MacCarthy PA, Kearney MT, Nolan J, Lee AJ, Prescott RJ, Shah AM, et al. Prognosis in heart failure with preserved left ventricular systolic function: prospective cohort study. BMJ. 2003;327:78–9.

    Article  PubMed Central  PubMed  Google Scholar 

  104. Lenzen MJ, Scholte op Reimer WJ, Boersma E, Vantrimpont PJ, Follath F, Swedberg K, et al. Differences between patients with a preserved and a depressed left ventricular function: a report from the EuroHeart Failure Survey. Eur Heart J. 2004;25:1214–20.

    Article  CAS  PubMed  Google Scholar 

Download references

Acknowledgments

Shannon M. Dunlay is supported by an NIH Career Development Award (K23 HL116643).

Compliance with Ethics Guidelines

Conflict of Interest

Shannon M. Dunlay and Véronique L. Roger declare that they have no conflict of interest.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Shannon M. Dunlay.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Dunlay, S.M., Roger, V.L. Understanding the Epidemic of Heart Failure: Past, Present, and Future. Curr Heart Fail Rep 11, 404–415 (2014). https://doi.org/10.1007/s11897-014-0220-x

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11897-014-0220-x

Keywords

Navigation