Skip to main content

Advertisement

SpringerLink
Log in

Validation of the Brazilian version of Chronic Liver Disease Questionnaire

  • Brief Communication
  • Published:
Quality of Life Research Aims and scope Submit manuscript

Abstract

Purpose

The aim of this study was to validate the Chronic Liver Disease Questionnaire (CLDQ) for use in Brazilian population.

Method

A total of 200 patients with chronic liver disease and varying disease severity answered a socio-demographic questionnaire, t CLDQ, and the Medical Outcome Study Short Form 36 (SF-36). Patients returned in 1–15 days to answer CLDQ again. The Cronbach’s alpha of the total CLDQ score was 0.95 and fluctuated between 0.69 and 0.83 in its six domains.

Results

The intra-class correlation between total CLDQ scores in two evaluations was 0.97 and in all domains was >0.93. CLDQ was moderately correlated with the SF-36, 0.63 (total CLDQ vs. vitality, SF-36), 0.62 (CLDQ and mental health, SF-36), 0.62 (preoccupation, CLDQ, vs. General Health, SF-36), 0.59 (fatigue, CLDQ, vs. vitality, SF-36), 0.59 (activity, CLDQ, vs. vitality, SF-36), and 0.59 (fatigue, CLDQ, vs. mental health, SF-36). The highest scores were found in non-cirrhotic group. Child A patients had higher average scores than Child B and C groups in all domains, while patients with MELD <15 scored higher than patients with MELD ≥15.

Conclusion

CLDQ-BR was validated in Brazilian population and was appropriate for use in patients with liver disease of different etiologies and degrees of severity.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Younossi, Z. M. (1998). Epidemiology of alcoholic liver disease. Clinical Liver Disease, 2(4), 661–671.

    Article  Google Scholar 

  2. [World Health Organization] Available from URL:http://www.who.int/mediacentre/factsheets/fs204/en/index.html accessed in [2003] (August, 2003).

  3. Younossi, Z. M., Boparai, N., Kiwi, M., Price, L., & Guyatt, G. (2001). Health-related quality of life assessment in chronic liver disease: impact of type and severity of disease. American Journal of Gastroenterology, 96(7), 2199–2205.

    Article  PubMed  CAS  Google Scholar 

  4. Bonkovsky, H. L., & Wooley, R. (1999). Reduction of health-related quality of life in HCV and improvement with interferon therapy. Hepatology, 29, 264–270.

    Article  PubMed  CAS  Google Scholar 

  5. Sumskiene, J., Sumskas, L., Petrauskas, D., & Kupcinskas, L. (2006). Disease-specific health-related quality of life and its determinants in liver cirrhosis patients in Lithuania. World Journal of Gastroenterology, 12(48), 7792–7797.

    PubMed  Google Scholar 

  6. Younossi, Z. M., McCormick, M., Boparai, N., Farquhar, L., Henderson, J. M., et al. (2000). The impact of liver transplantation on health-related quality of life. Liver Transplantation, 6, 779–783.

    Article  PubMed  CAS  Google Scholar 

  7. O′Carrol, R. E., Couston, M., Cossar, J., Masterton, G., & Hayes, P. C. (2003). Psychological outcome and quality of life following liver transplantation: a prospective, national, single-center study. Liver Transplantation, 9, 712–720.

    Article  Google Scholar 

  8. Bravata, D. M., Olkin, I., Barnato, A. E., Keeffe, E. B., & Owens, D. K. (1999). Health-related quality of Life after liver transplantation: a meta-analysis. Liver Transplantation and Surgery, 5(4), 318–331.

    Article  PubMed  CAS  Google Scholar 

  9. Younossi, Z. M., Guyatt, G., Kiwi, M., Boparai, N., & King, D. (1999). Development of a disease specific questionnaire to measure health related quality of life in patients with chronic liver disease. Gut, 45, 295–300.

    Article  PubMed  CAS  Google Scholar 

  10. Häuser, W., Schnur, M., Steder-Neukamm, U., Muthny, F. A., & Grandt, D. (2004). Validation of the German version of the chronic liver disease questionnaire. European Journal of Gastroenterology and Hepatology, 16(6), 599–605.

    Article  PubMed  Google Scholar 

  11. Sobhonslidsuk, A., Silpakit, C., Kongsakon, R., SatitpornKul, P., & Sripetch, C. (2004). Chronic liver disease questionnaire: translation and validation in Thai. World Journal of Gastroenterology, 10(13), 1954–1957.

    PubMed  Google Scholar 

  12. Ferrer, M., Córdoba, J., Garin, O., Olivé, G., Flávia, M., Vargas, V., et al. (2006). Validity of the Spanish version of the Chronic Liver Disease Questionnaire (CLDQ) as a standard outcome for quality of life assessment. Liver Transplantation, 12(1), 95–104.

    Article  PubMed  Google Scholar 

  13. Rucci, P., Taliani, G., Cirrincione, L., Alberti, A., Bartolozzi, D., Caporaso, N., et al. (2005). Validity and reliability of the Italian version of the Chronic Liver Disease Questionnaire (CLDQ-I) for the assessment of health related quality of life. Digestive and Liver Disease, 37(11), 850–860.

    Article  PubMed  CAS  Google Scholar 

  14. Kollia, Z., Patelarou, E., Vivilaki, V., Kollia, E., Kefou, F., Elefsiniotis, I., et al. (2010). Translation and validation of the Greek chronic liver disease questionnaire. World Journal of Gastroenterology, 16(46), 5838–5844.

    Article  PubMed  Google Scholar 

  15. Ray, I., Dutta, D., Basu, P., & De, B. K. (2010). Quality of life assessment of patients with chronic liver disease in eastern India using a Bengali translation chronic liver disease questionnaire. Indian Journal of Gastroenterology, 29(5), 187–195.

    Article  PubMed  Google Scholar 

  16. Lam, E. T., Lam, C. L., Lai, C. L., Yuen, M. F., & Fong, D. Y. (2009). Psychometrics of the chronic liver disease questionnaire for Southern Chinese patients with chronic hepatitis B virus infection. World Journal of Gastroenterology, 15(26), 3288–3297.

    Article  PubMed  Google Scholar 

  17. Mahmoudi, H., Jafari, P., Alizadeh-Naini, M., Gholami, S., Malek-Hosseini, S.A., Ghaffaripour, S. (2011) Validity and reliability of Persian version of chronic liver disease questionnaire (CLDQ). Quality of Life Research 20(1), 1–7.

    Google Scholar 

  18. Ciconelli, R. M., Ferraz, M. B., Santos, W., Meinão, I., & Quaresma, M. R. (1999). Tradução para a língua portuguesa e validação do questionário genérico de avaliação de qualidade de vida SF-36. Revista Brasileira de Reumatologia, 39(3), 143–149.

    Google Scholar 

  19. Mucci, S., Citero, V. A., & Nogueira-Martins, L. A. (2005). Tradução e adaptação transcultural do instrumento de qualidade de vida específico para pacientes com hepatopatia crônica-Chronic Liver Disease Questionnaire (CLDQ). Revista Brasileira de Psiquiatria, 27, 60.

    Google Scholar 

  20. Child, C. G., & Turcotte, J. G. (1964). Surgery and portal hypertension: Major Problems. Clinical Surgery, 1, 1–85.

    CAS  Google Scholar 

  21. Wesner, R., Lake, J. R., Freeman, R. B., & Gish, R. G. (2006). Model for end-stage liver disease (MELD) exception guidelines. Liver Transplantation, 12(suppl 3), 85–87.

    Article  Google Scholar 

  22. Reichenheim, M. E., & Moraes, C. L. (2007). Operationalizing the cross-cultural adaptation of epidemiological measurement instruments. Revista de Saúde Pública, 41(4), 665–673.

    Article  PubMed  Google Scholar 

  23. Freeman, R. B. (2005). MELD and the quality of life. Liver Transplantation, 11(2), 218–223.

    Article  Google Scholar 

  24. Wilson, J., & Cleary, P. (1995). Linking clinical variables with health related quality of life. JAMA, 273, 59–65.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Psychiatry, Universidade Federal de São Paulo, São Paulo, Brazil

    Samantha Mucci, Vanessa de Albuquerque Citero, Luciana Geocze, Mario Alfredo De Marco & Luiz Antonio Nogueira Martins

  2. Department of Surgical Gastroenterology, Universidade Federal de São Paulo, São Paulo, Brazil

    Adriano Miziara Gonzalez & Gaspar de Jesus Lopes Filho

  3. Department of Clinical Gastroenterology, Universidade Federal de São Paulo, São Paulo, Brazil

    Stephan Geocze & Edison Roberto Parise

Authors
  1. Samantha Mucci
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Vanessa de Albuquerque Citero
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Adriano Miziara Gonzalez
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Luciana Geocze
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Stephan Geocze
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Gaspar de Jesus Lopes Filho
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Mario Alfredo De Marco
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Edison Roberto Parise
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. Luiz Antonio Nogueira Martins
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Samantha Mucci.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Mucci, S., de Albuquerque Citero, V., Gonzalez, A.M. et al. Validation of the Brazilian version of Chronic Liver Disease Questionnaire. Qual Life Res 22, 167–172 (2013). https://doi.org/10.1007/s11136-012-0138-2

Download citation

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11136-012-0138-2

Keywords

Search

Navigation