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X-Chromosome STR markers data in a Cabo Verde immigrant population of Lisboa

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Abstract

Population genetic data of 12 X chromosomal short tandem repeats markers (DXS10074, DXS10079, DXS10101, DXS10103, DXS10134, DXS10135, DXS10146, DXS10148, DXS7132, DXS7423, DXS8378 and HPRTB) were analysed in 54 females and 95 males of an immigrant population from Cabo Verde living in Lisboa. The obtained results for forensic statistical parameters such as observed heterozigosity, polymorphism information content, power of discrimination and mean exclusion chance, based on single allele frequencies, reveal that this multiplex system is highly informative and can represent an important tool for genetic identification purposes in the immigrant population of Cabo Verde. Since the studied short tandem repeats genetic markers are distributed on four linkage groups, that can provide independent genotype information, we studied those groups as haploytes. The forensic efficiency parameters for the linked groups were all higher than 0.97, with linkage group I being the most polymorphic and linkage group III the less informative.

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Authors and Affiliations

  1. Serviço de Genética e Biologia Forenses, Instituto Nacional de Medicina Legal e Ciências Forenses I.P., Delegação do Sul, Rua Manuel Bento de Sousa, no. 3, 1169-201, Lisboa, Portugal

    Heloísa Afonso Costa, Paulo Morais, Cláudia Vieira da Silva, Sara Matos, Rodolfo Marques Santos, Rosa Espinheira & António Amorim

  2. Serviço de Clínica Forense, Instituto Nacional de Medicina Legal e Ciências Forenses, I.P., Delegação do Sul, Lisbon, Portugal

    Jorge Costa Santos

  3. Medicina Legal e Ciências Forenses, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal

    Jorge Costa Santos

  4. Ciências Forenses e Criminais, Instituto Superior de Ciências de Saúde Egas Moniz, Caparica, Portugal

    António Amorim

  5. Biologia Molecular em Saúde, Escola Superior de Saúde Egas Moniz, Almada, Portugal

    Paulo Morais & Sara Matos

  6. CENCIFOR - Centro de Ciências Forenses, Largo da Sé Nova, Coimbra, Portugal

    Heloísa Afonso Costa, Cláudia Vieira da Silva, Rodolfo Marques Santos, Rosa Espinheira, Jorge Costa Santos & António Amorim

Authors
  1. Heloísa Afonso Costa
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  2. Paulo Morais
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  3. Cláudia Vieira da Silva
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  4. Sara Matos
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  5. Rodolfo Marques Santos
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  6. Rosa Espinheira
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  7. Jorge Costa Santos
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  8. António Amorim
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Correspondence to Heloísa Afonso Costa.

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Afonso Costa, H., Morais, P., Vieira da Silva, C. et al. X-Chromosome STR markers data in a Cabo Verde immigrant population of Lisboa. Mol Biol Rep 41, 2559–2569 (2014). https://doi.org/10.1007/s11033-014-3114-9

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  • DOI: https://doi.org/10.1007/s11033-014-3114-9

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