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Neuroticism and Physical Disorders Among Adults in the Community: Results from the National Comorbidity Survey

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To examine the association between neuroticism and physical disorders among adults in the United States, data were drawn from the National Comorbidity Survey (n = 5877). Multiple logistic regression analyses were used to examine the relationship between neuroticism and physical disorders among adults in the community, adjusting for differences in demographic characteristics and comorbid mental disorders.Results indicated that neuroticism was associated with significantly elevated rates of a wide range of physical disorders, with the exception of stroke. After adjusting for differences in demographic characteristics and comorbid mental disorders, neuroticism was associated with increased odds of arthritis (OR = 1.5), diabetes (OR = 3.33), kidney/liver disease (OR = 2.56), stomach/gallbladder problems (OR = 2.27), and ulcer (OR = 3.23). Based on those findings, neuroticism appears to be a general predictor of a range of physical health problems among adults in the United States. Much of this association appears to be partially mediated by comorbid mental disorders, yet the association between neuroticism and arthritis, diabetes, kidney/liver disease, stomach problems, and ulcer persist even after adjusting for differences in demographic characteristics and comorbid mental disorders. Future studies that can examine the nature and mechanism of these linkages across the lifespan are needed next.

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REFERENCES

  • Aarstad, H. J., Heimdal, J. H., Aarsta, A. K., and Olofsson, J. (2002). Personality traits in head and neck squamous cell carcinoma patients in relation to the disease state, disease extent and prognosis. Acta Otolaryngol. 122: 892–899.

    Article  PubMed  Google Scholar 

  • Appelberg, K., Romanov, K., Heikkila, K., Honkasalo, M. L., and Koskenvuo, M. (1996). Interpersonal conflict as a predictor of work disability: A follow-up study of 15, 348 Finnish employees. J. Psychsom. Res. 40: 157–167.

    Article  Google Scholar 

  • Asghari, A., and Nicholas, M. K. (2006). Personality and pain-related beliefs/coping strategies: A prospective study. Clin. J. Pain 22: 10–18.

    Article  PubMed  Google Scholar 

  • Baron, R. M., and Kenny, D. A. (1986). The moderator–mediator variable distinction in social psychological research: Conceptual, strategic, and statistical considerations. J. Pers. Soc. Psychol. 51: 1173–1182.

    Article  PubMed  Google Scholar 

  • Belsky, J., Crnic, K., and Woodworth, S. (1995). Personality and parenting: Exploring the mediating role of transient mood and daily hassles. J. Pers. 63: 905–929.

    Article  PubMed  Google Scholar 

  • Bienvenu, O. J., Samuels, G. F., Costa, P. T., Howard, W. T., and Eaton, W. W. (2001). Phobic, panic, and major depressive disorders and the five-factor model of personality. J. Nerv. Ment. Dis. 189: 154–161.

    Article  PubMed  Google Scholar 

  • Brickman, A. L., Yount, S. E., Blaney, N. T., Rothberg, S. T., and De-Nour, A. K. (1996). Personality traits and long-term health status. The influence of neuroticism and conscientiousness on renal deterioration in type-1 diabetes. Psychosomatics 37: 459–468.

    PubMed  Google Scholar 

  • Charles, S. T., Gatz, M., Pedersen, N. L., and Dahlberg, L. (1999). Genetic and behavioral risk factors for self-reported joint pain among a population-based sample of Swedish twins. Health Psychol. 18: 644–654.

    Article  PubMed  Google Scholar 

  • Costa, P. T., and McCrae, R. R. (1980a). Influence of extraversion and neuroticism on subjective well-being: Happy and unhappy people. J. Pers. Soc. Psychol. 38: 668–678.

    Article  PubMed  Google Scholar 

  • Costa, P. T., and McCrae, R. R. (1980b). Somatic complaints in males as a function of age, and neuroticism: A longitudinal analysis. J. Behav. Med. 3: 245–257.

    Article  PubMed  Google Scholar 

  • Costa, P. T., and McCrae, R. R. (1982). Neuroticism, coronary artery disease, and chest pain complaints: Cross-sectional and longitudinal studies. Exp. Aging Res. 8: 37–44.

    Google Scholar 

  • Costa, P. T., and McCrae, R. R. (1985). Hypochondriasis, neuroticism, and aging: When are somatic complaints unfounded? Am. Psychol. 40: 19–28.

    Article  PubMed  Google Scholar 

  • Costa, P. T., and McCrae, R. R. (1987). Neuroticism, somatic complaints, and disease: Is the bark worse than the bite? J. Pers. 55: 299–316.

    Article  PubMed  Google Scholar 

  • Costa, P. T., McCrae, R. R., and Norris, A. H. (1981). Personal adjustment to aging: Longitudinal prediction from neuroticism and extraversion. J. Gerentol. 36: 78–85.

    Google Scholar 

  • Cox, B. J., McWilliams, L. A., and Enns, M. W. (2004). Broad and specific personality dimensions associated with major depression in a nationally representative sample. Compr. Psychiatry 45: 246–253.

    Article  PubMed  Google Scholar 

  • Cramer, D. (1994). Psychological distress and neuroticism: A two-wave panel study. Br. J. Med. Psychol. 67: 333–342.

    PubMed  Google Scholar 

  • David, J. P., Green, P. J., Martin, R., and Suls, J. (1997). Differential roles of neuroticism, extraversion, and even desirability for mood in daily life: An integrative model of top-down and bottom-up influences. J. Pers. Soc. Psychol. 73: 149–159.

    Article  PubMed  Google Scholar 

  • David, J. P., and Suls, J. (1999). Coping efforts in daily life: Role of big five traits and problem appraisals. J. Pers. 67: 265–294.

    Article  PubMed  Google Scholar 

  • De Beurs, E., Beekman, A. T., Deeg, D. J., Van Dyck, R., and van Tiberg, W. (2000). Predictors of change in anxiety symptoms of older persons: Results from the longitudinal aging study of Amsterdam. Psychol. Med. 30: 515–527.

    Article  PubMed  Google Scholar 

  • De Graaf, R., Bijl, R. V., Ravelli, A., Smit, F., and Vollebergh, W. A. (2002). Predictors of first incidence of DSM-III-R psychiatric disorders in the general population: Findings from the Netherlands Mental Health Survey and Incidence Study. Acta Psychiatr. Scand. 106: 303–313.

    Article  PubMed  Google Scholar 

  • Digman, J. M. (1990). Personality structure: Emergence of the five-factor model. Ann. Rev. Psychol. 41: 417–440.

    Google Scholar 

  • Egger, H. L., Costello, E. J., Erkanli, A., and Angold, A. (1999). Somatic complaints and psychopathology in children and adolescents: Stomach aches, musculoskeletal pains, and headaches. J. Am. Acad. Child Adolesc. Psychiatry. 38: 852–860.

    Article  PubMed  Google Scholar 

  • Fanous, A., Gardner, C. O., Prescott, C. A., Cancro, R., and Kendler, K. S. (2002). Neuroticism, major depression, and gender: A population-based twin study. Psychol. Med. 32: 719–728.

    Article  PubMed  Google Scholar 

  • Feeney, S. L. (2004). The relationship between pain and negative affect in older adults: Anxiety as a predictor of pain. J. Anxiety Disord. 18: 733–744.

    Article  PubMed  Google Scholar 

  • Fergusson, D. M., and Horwood, L. J. (1997). Vulnerability to life events exposure. Psychol. Med. 17: 739–49.

    Google Scholar 

  • For-Wey, L., Fei-Yin, L., and Bih-Ching, S. (2002). The relationship between life adjustment and parental bonding in military personnel with adjustment disorder in Taiwan. Mil. Med. 167: 678–682.

    PubMed  Google Scholar 

  • Goldberg, L. R. (1992). The development of markers for the big-five factor structure. Psychol. Assess. 4: 26–42.

    Article  Google Scholar 

  • Goodwin, R. D., and Engstrom, G. (2002). Personality and the perception of health in the general population. Psychol. Med. 32: 325–332.

    PubMed  Google Scholar 

  • Goodwin, R. D., and Hamilton, S. P. (2002). Cigarette smoking and panic: The role of neuroticism. Am. J. Psychiatry 159: 1208–1213.

    Article  PubMed  Google Scholar 

  • Goodwin, R. D., and Stein, M. B. (under review). Personality factors and occupational disability among adults in the community.

  • Gordon, D., Fisher, S. G., Wilson, M., Fergus, E., Paterson, K. R., and Semple, C. G. (1993). Psychological factors and their relationship to diabetes control. Diabet. Med. 10: 530–534.

    PubMed  Google Scholar 

  • Goubert, L., Crombez, G., and Van Damme, S. (2004). The role of neuroticism, pain catastrophizing and pain-related fear in vigilance to pain: A structural equations approach. Pain 107: 234–241.

    Article  PubMed  Google Scholar 

  • Hayden, E. P., and Klein, D. N. (2001). Outcome of dysthymic disorder at 5-year follow-up: The effects of familial psychopathology, early adversity, personality, comorbidity, and chronic stress. Am. J. Psychiatry 158: 1864–1870.

    Article  PubMed  Google Scholar 

  • Horwood, L. J., and Fergusson, D. M. (1996). Neuroticism, depression and life events: A structural equation model. Soc. Psychiatry 21: 63–71.

    Article  Google Scholar 

  • Jain, A. K., Gupta, J. P., Gupta, S., Rao, K. P., and Bahre, P. B. (1995). Neuroticism and stressful life events in patients with non-ulcer dyspepsia. J. Assoc. Physicians India 43: 90–91.

    PubMed  Google Scholar 

  • Jang, Y., Mortimer, J. A., Haley, W. E., Chisolm, T. E., and Graves, A. B. (2002). Nonauditory determinants of self-perceived hearing problems among older adults: The role of stressful life conditions, neuroticism, and social resources. J. Gerontol. A Biol. Sci. Med. Sci. 57: 466–469.

    Google Scholar 

  • Johnson, W., and Krueger, R. F. (2005). Predictors of physical health: Toward an integrated model of genetic and environmental antecedents. J. Gerontol. B Psychol. Sci. Soc. Sci. 60: 42–52.

    PubMed  Google Scholar 

  • Jorm, A. F., Rodgers, B., Jacomb, P. A., Christensen, H., Henderson, S., and Korten, A. E. (1999). Smoking and mental health: Results from a community survey. Med. J. Aust. 18, 74–77.

    Google Scholar 

  • Kessler, R. C., Little, R. J. A., and Groves, R. M. (1995). Advances in strategies for minimizing and adjusting for survey nonresponse. Epidemiol. Rev. 17: 192–204.

    PubMed  Google Scholar 

  • Kessler, R. C., McGonagle, K. A., Zhao, S., Nelson, C. B., Hughes, M., Eshleman, H. U., Wittchen, H. U., and Kendler, K. S. (1994). Lifetime and 12–month prevalence of DSM-III-R psychiatric disorders in the United States: Results from the National Comorbidity Survey. Arch. Gen. Psychiatry 51: 8–19.

    PubMed  Google Scholar 

  • King, A. C., Bernardy, N. C., and Hauner, K. (2003). Stressful events, personality, and mood disturbance: Gender differences in alcoholics and problems drinkers. Addict. Behav. 28: 171–187.

    Article  PubMed  Google Scholar 

  • Kuh, D., Hardy, R., Rodgers, B., and Wadsworth, M. E. (2002). Lifetime risk factors for women's psychological distress in midlife. Soc. Sci. Med. 55: 1957–1973.

    Article  PubMed  Google Scholar 

  • Krueger, R. F., Caspi, A., Moffitt, T. E., and Silva, P. A. (1998). The structure and stability of common mental disorders (DSM-III-R): A longitudinal-epidemiological study. J. Abnorm. Psychol. 107: 216–227.

    Article  PubMed  Google Scholar 

  • Levenstein, S. (2002). Bellyaching in these pages: Upper gastrointestinal disorders in psychosomatic medicine. Psychosom. Med. 64: 767–772.

    Article  PubMed  Google Scholar 

  • Lu, L. (1994). University transition: Major and minor life stressors, personality characteristics, and mental health. Psychol. Med. 24: 81–87.

    PubMed  Google Scholar 

  • McCrae, R. R., Costa, P. T., and Bosse, R. (1978). Anxiety, extraversion, and smoking. Br. J. Soc. Clin. Psychol. 17: 269–273.

    PubMed  Google Scholar 

  • McLennan, J., Buchanan, J. I., and Bates, G. W. (1994). Neuroticism and negative affect measures as predictors of psychological distress. Psychol. Rep. 75: 305–306.

    PubMed  Google Scholar 

  • Podar, I., Hannus, A., and Allik, J. (1999). Personality and affectivity characteristics associated with eating disorders: A comparison of eating disordered, weight-preoccupied, and normal samples. J. Pers. Assess. 73: 133–147.

    Article  PubMed  Google Scholar 

  • Poulton, R. G., and Andrews, G. (1992). Personality as a cause of adverse life events. Acta. Psychiatr. Scand. 85: 35–38.

    Article  PubMed  Google Scholar 

  • Research Triangle Institute (2000). Software for the statistical analysis of correlated data (SUDDAN), Release 7.5. Research Triangle Institute, Research Triangle Park, NC.

  • Roberts, S. B., and Kendler, K. S. (1999). Neuroticism and self-esteem as indices of the vulnerability to major depression in women. Psychol. Med. 29: 1101–1119.

    Article  PubMed  Google Scholar 

  • Shiner, R. L., Masten, A. S., and Roberts, J. M. (2003). Childhood personality foreshadows adult personality and life outcomes two decades later. J. Pers. 7: 1145–1170.

    Article  Google Scholar 

  • Steel, P., and Ones, D. S. (2002). Personality and happiness: A national-level analysis. J. Pers. Soc. Psychol. 83: 767–781.

    Article  PubMed  Google Scholar 

  • Talley, N. J., Boyce, P. M., and Jones, M. (1997). Predictors of health care seeking for irritable bowel syndrome: A population based study. Gut 41: 394–398.

    PubMed  Google Scholar 

  • Talley, N. J., Boyce, P. M., and Jones, M. (1998). Is the association between irritable bowel syndrome and abuse explained by neuroticism? Gut 42: 47–53.

    Article  PubMed  Google Scholar 

  • Van Os, J., and Jones, P. B. (2001). Neuroticism as a risk factor for schizophrenia. Psychol. Med. 31: 1129–1134.

    Article  PubMed  Google Scholar 

  • Wade, J. B., Dougherty, L. M., Hart, R. P., Rafii, A., and Price, D. D. (1992). A canonical correlation analysis of theinfluence of neuroticism and extraversion on chronic pain, suffering, and pain behavior.Pain. 51: 67–73.

    Article  PubMed  Google Scholar 

  • Wilson, K. C., Whiteoak, R., Dewey, M., and Watson, J. P. (1989). Aspects of personality of soldiers presenting to an endoscopy clinic. J. Psychosom. Res. 33: 85–91.

    Article  PubMed  Google Scholar 

  • Wittchen, H. U. (1994). Reliability and validity studies of the WHO Composite International Diagnostic Interview (CIDI): A critical review. J. Psychiatric. Res. 28: 57–84.

    Article  Google Scholar 

  • Wittchen, H. U., Kessler, R. C., Zhao, S., and Abelson, J. (1995). Reliability and clinical validity of UM-CIDI DSM-III-R generalized anxiety disorder. J. Psychiatric. Res. 29: 95–110.

    Article  Google Scholar 

  • Wittchen, H. U., Zhao, S., Abelson, J. M., Abelson, J. L., and Kessler, R. C. (1996). Reliability and procedural validity of UM-CIDI DSM-III-R phobic disorders. Psychol. Med. 25: 1169–1177.

    Article  Google Scholar 

  • World Health Organization (1990). Composite International Diagnostic Interview (CIDI), version 1.0. Geneva, WHO.

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Goodwin, R.D., Cox, B.J. & Clara, I. Neuroticism and Physical Disorders Among Adults in the Community: Results from the National Comorbidity Survey. J Behav Med 29, 229–238 (2006). https://doi.org/10.1007/s10865-006-9048-5

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