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Regression of severe corneal stromal neovascularization with topical cyclosporine 0.05% after penetrating keratoplasty for fungal corneal ulcer

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Abstract

Purpose To report regression of corneal stromal neovascularizations with the use of topical cyclosporine 0.05% in a corneal transplant patient performed for fungal corneal ulcer. Design Case report. Methods A 14-year-old boy treated for fungal corneal ulceration developed 360° corneal stromal neovascularization peroperatively. Topical cyclosporine 0.05% was used to decrease the risk of rejection. Results The neovascularizations regressed totally within 2 months and no signs of graft rejection were present at 6 months follow up. Conclusion Topical cyclosporine 0.05% may result in regression of stromal corneal neovascularizations and help to reduce the risk of graft rejection in selected cases.

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Correspondence to Baris Sonmez.

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Sonmez, B., Beden, Ü. & Erkan, D. Regression of severe corneal stromal neovascularization with topical cyclosporine 0.05% after penetrating keratoplasty for fungal corneal ulcer. Int Ophthalmol 29, 123–125 (2009). https://doi.org/10.1007/s10792-007-9180-4

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  • DOI: https://doi.org/10.1007/s10792-007-9180-4

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