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The Trend of Inflammatory Bowel Diseases in Taiwan: A Population-Based Study

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Abstract

Background and Aim

The purpose of this study was to estimate the sex- and age-specific incidence rates of inflammatory bowel diseases (IBD) in Taiwan. Site-specific cancer occurred in patients with IBD would be reported, too.

Methods

A retrospective study by analyzing the data from the National Health Insurance Research Database of Taiwan.

Results

Between 2000 and 2010, the overall incidence rate of Crohn’s disease (CD) and ulcerative colitis (UC) was 0.208 and 0.838 per 100,000 person-years. For male, the incidence rate of CD was 0.195 (95 % CI 0.113–0.276) per 100,000 persons in 2000 and increased to 0.318 (95 % CI 0.216–0.421) per 100,000 persons in 2010. For female, the incidence rate of CD was 0.092 (95 % CI 0.035–0.149) per 100,000 persons in 2000 and increased to 0.210 (95 % CI 0.128–0.293) per 100,000 persons in 2010. For male, the incidence rate of UC was 0.690 (95 % CI 0.537–0.843) per 100,000 persons in 2000 and increased to 1.351 (95 % CI, 1.140–1.562) per 100,000 persons in 2010. For female, the incidence rate of UC was 0.386 (95 % CI 0.269–0.503) per 100,000 persons in 2000 and increased to 0.858 (95 % CI 0.691–1.024) per 100,000 persons in 2010. Among the CD patients, 0.19 % had colorectal cancers (1/519). Among the UC patients, 0.24 % had colorectal cancers (5/2098).

Conclusions

This nationwide population-based longitudinal epidemiological study of IBD in Taiwan provides data for future global comparisons.

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Acknowledgments

CJ Kuo, KH Yu, CT Chiu, MY Su, CM Hsu, CF Kuo, and HW Wang developed the study concept and design and provided the critical revision of the manuscript for important intellectual content. LC See, MJ Chiou, and JR Liu collected and interpreted the data. All authors approved the final version of the manuscript.

Conflict of interest

The authors report no conflicts of interest.

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Authors and Affiliations

  1. Department of Gastroenterology and Hepatology, College of Medicine, Chang Gung Memorial Hospital, Chang Gung University, 5, Fushin Street, Kweishan, Taoyuan, Taiwan, ROC

    Chia-Jung Kuo, Cheng-Tang Chiu, Ming-Yao Su, Chen-Ming Hsu & Hung-Wei Wang

  2. College of Medicine, Chang Gung University, Taoyuan, Taiwan, ROC

    Chia-Jung Kuo, Kuang-Hui Yu, Lai-Chu See, Cheng-Tang Chiu, Ming-Yao Su, Chen-Ming Hsu, Chang-Fu Kuo, Meng-Jiun Chiou & Jia-Rou Liu

  3. Division of Rheumatology, Allergy, and Immunology, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC

    Kuang-Hui Yu & Chang-Fu Kuo

  4. Department of Public Health, Biostatistics Consulting Center, Chang Gung University, Taoyuan, Taiwan, ROC

    Lai-Chu See, Meng-Jiun Chiou & Jia-Rou Liu

  5. Biostatistics Core Laboratory, Molecular Medical Research Center, Chang Gung University, Taoyuan, Taiwan, ROC

    Lai-Chu See, Meng-Jiun Chiou & Jia-Rou Liu

Authors
  1. Chia-Jung Kuo
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  2. Kuang-Hui Yu
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Corresponding author

Correspondence to Cheng-Tang Chiu.

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Kuo, CJ., Yu, KH., See, LC. et al. The Trend of Inflammatory Bowel Diseases in Taiwan: A Population-Based Study. Dig Dis Sci 60, 2454–2462 (2015). https://doi.org/10.1007/s10620-015-3630-z

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  • DOI: https://doi.org/10.1007/s10620-015-3630-z

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