Skip to main content
Log in

Feasibility of a single-beat prospective ECG-gated cardiac CT for comprehensive evaluation of aortic valve disease using a 256-detector row wide-volume CT scanner: an initial experience

  • Original Paper
  • Published:
The International Journal of Cardiovascular Imaging Aims and scope Submit manuscript

Abstract

The aim of our study was to investigate the feasibility of single-beat prospective electrocardiogram (ECG)-gated cardiac computed tomography (CT) using a 256-detector row wide-volume CT scanner for functional and anatomical evaluation of the aortic valve (AV) and coronary arteries in patients with AV disease. A total of 50 patients who underwent cardiac CT scan with a wide-volume 256-detector row CT scanner for the evaluation of AV and aorta were retrospectively enrolled. Cardiac CT was performed using the prospective ECG-gated acquisition mode, and AV image quality was analyzed using a four-point grading system. Severity of aortic stenosis (AS) and aortic regurgitation (AR) were assessed by CT and correlated to that assessed by transthoracic echocardiography (TTE) based on kappa statistics (κ). Estimated radiation exposure was assessed. Among 50 patients, 44 underwent cardiac CT with single-beat acquisition. The median image quality score of AV was 3.0 on the systolic phase and 4.0 on the diastolic phase. Severity of AS and AR by CT showed moderate agreement with TTE. The mean effective radiation dose was 3.75 ± 1.43 mSv for CT angiography. Using 256-detector row wide-volume CT, the single-beat cardiac CT is feasible for evaluation of AV disease and the coronary arteries, with acceptable image quality and a low radiation dose of 3.75 mSv.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4

Similar content being viewed by others

Abbreviations

TTE:

Transthoracic echocardiography

AS:

Aortic stenosis

AR:

Aortic regurgitation

AVA:

Aortic valve area

ROA:

Regurgitant orifice area

DLP:

Dose-length product

mSv:

Millisieverts

References

  1. Sawaya F, Liff D, Stewart J, Lerakis S, Babaliaros V (2012) Aortic stenosis: a contemporary review. Am J Med Sci 343(6):490–496

    Article  PubMed  Google Scholar 

  2. Baumgartner H, Hung J, Bermejo J et al (2009) Echocardiographic assessment of valve stenosis: EAE/ASE recommendations for clinical practice. Eur J Echocardiogr 10(1):1–25

    Article  PubMed  Google Scholar 

  3. Weinreb JC, Larson PA, Woodard PK et al (2005) American College of Radiology clinical statement on noninvasive cardiac imaging. Radiology 235(3):723–727

    Article  PubMed  Google Scholar 

  4. Achenbach S, Delgado V, Hausleiter J, Schoenhagen P, Min JK, Leipsic JA (2012) SCCT expert consensus document on computed tomography imaging before transcatheter aortic valve implantation (TAVI)/transcatheter aortic valve replacement (TAVR). J Cardiovasc Comput Tomogr 6(6):366–380

    Article  PubMed  Google Scholar 

  5. Opolski MP, Staruch AD, Jakubczyk M et al (2016) CT angiography for the detection of coronary artery stenoses in patients referred for cardiac valve surgery: systematic review and meta-analysis. JACC Cardiovasc Imaging. doi:10.1016/j.jcmg.2015.09.028

    PubMed  Google Scholar 

  6. Pouleur AC, le Polain de Waroux JB, Pasquet A, Vanoverschelde JL, Gerber BL (2007) Aortic valve area assessment: multidetector CT compared with cine MR imaging and transthoracic and transesophageal echocardiography. Radiology 244(3):745–754

    Article  PubMed  Google Scholar 

  7. Alkadhi H, Desbiolles L, Husmann L et al (2007) Aortic regurgitation: assessment with 64-section CT. Radiology 245(1):111–121

    Article  PubMed  Google Scholar 

  8. Jeon MH, Choe YH, Cho SJ, Park SW, Park PW, Oh JK (2010) Planimetric measurement of the regurgitant orifice area using multidetector CT for aortic regurgitation: a comparison with the use of echocardiography. Korean J Radiol 11(2):169–177

    Article  PubMed  PubMed Central  Google Scholar 

  9. Clavel MA, Malouf J, Messika-Zeitoun D, Araoz PA, Michelena HI, Enriquez-Sarano M (2015) Aortic valve area calculation in aortic stenosis by CT and Doppler echocardiography. JACC Cardiovasc Imaging 8(3):248–257

    Article  PubMed  Google Scholar 

  10. Hirai N, Horiguchi J, Fujioka C et al (2008) Prospective versus retrospective ECG-gated 64-detector coronary CT angiography: assessment of image quality, stenosis, and radiation dose. Radiology 248(2):424–430

    Article  PubMed  Google Scholar 

  11. Einstein AJ, Elliston CD, Arai AE et al (2010) Radiation dose from single-heartbeat coronary CT angiography performed with a 320–detector row volume scanner. Radiology 254(3):698–706

    Article  PubMed  PubMed Central  Google Scholar 

  12. Qin J, Liu LY, Fang Y et al (2012) 320-detector CT coronary angiography with prospective and retrospective electrocardiogram gating in a single heartbeat: comparison of image quality and radiation dose. Br J Radiol 85(1015):945–951

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  13. Shuman WP, Branch KR, May JM et al (2008) Prospective versus retrospective ECG gating for 64-detector CT of the coronary arteries: comparison of image quality and patient radiation dose. Radiology 248(2):431–437

    Article  PubMed  Google Scholar 

  14. Choo WS, Steeds RP (2011) Cardiac imaging in valvular heart disease. Br J Radiol 84(Spec No 3):S245–S257

    Article  PubMed  PubMed Central  Google Scholar 

  15. Lancellotti P, Tribouilloy C, Hagendorff A et al (2010) European Association of Echocardiography recommendations for the assessment of valvular regurgitation. Part 1: aortic and pulmonary regurgitation (native valve disease). Eur J Echocardiogr 11(3):223–244

    Article  PubMed  Google Scholar 

  16. Halliburton SS, Abbara S, Chen MY et al (2011) SCCT guidelines on radiation dose and dose-optimization strategies in cardiovascular CT. J Cardiovasc Comput Tomogr 5(4):198–224

    Article  PubMed  PubMed Central  Google Scholar 

  17. Halpern EJ, Mallya R, Sewell M, Shulman M, Zwas DR (2009) Differences in aortic valve area measured with CT planimetry and echocardiography (continuity equation) are related to divergent estimates of left ventricular outflow tract area. AJR Am J Roentgenol 192(6):1668–1673

    Article  PubMed  Google Scholar 

  18. Mullany CJ, Elveback LR, Frye RL et al (1987) Coronary artery disease and its management: influence on survival in patients undergoing aortic valve replacement. J Am Coll Cardiol 10(1):66–72

    Article  CAS  PubMed  Google Scholar 

  19. Thalji NM, Suri RM, Daly RC et al (2015) The prognostic impact of concomitant coronary artery bypass grafting during aortic valve surgery: implications for revascularization in the transcatheter era. J Thorac Cardiovasc Surg 149(2):451–460

    Article  PubMed  Google Scholar 

  20. Kurlansky PA, Williams DB, Traad EA, Carrillo RG, Zucker M, Ebra G (2007) Surgical management of aortic valve disease in elderly patients with and without coronary artery disease: influence on quality of life. J Cardiovasc Surg 48(2):215–226

    CAS  Google Scholar 

  21. Han K, Yang DH, Shin SY et al (2015) Subprosthetic pannus after aortic valve replacement surgery: cardiac CT findings and clinical features. Radiology 276(3):724–731

    Article  PubMed  Google Scholar 

  22. Latif MA, Sanchez FW, Sayegh K et al (2016) Volumetric single-beat coronary computed tomography angiography: relationship of image quality, heart rate, and body mass index. Initial patient experience with a new computed tomography scanner. J Comput Assist Tomogr 40(5):763–772

    Article  PubMed  Google Scholar 

  23. Soon J, Sulaiman N, Park JK et al (2016) The effect of a whole heart motion-correction algorithm on CT image quality and measurement reproducibility in Pre-TAVR aortic annulus evaluation. J Cardiovasc Comput Tomogr 10(5):386–390

    Article  PubMed  Google Scholar 

  24. Bennett CJ, Maleszewski JJ, Araoz PA (2012) CT and MR imaging of the aortic valve: radiologic-pathologic correlation. Radiographics 32(5):1399–1420

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Young Joo Suh.

Ethics declarations

Conflict of interest

All authors declare that there are no conflicts of interest.

Electronic supplementary material

Below is the link to the electronic supplementary material.

Supplementary material 1 (DOCX 20 KB)

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Kim, J.Y., Suh, Y.J., Chang, S. et al. Feasibility of a single-beat prospective ECG-gated cardiac CT for comprehensive evaluation of aortic valve disease using a 256-detector row wide-volume CT scanner: an initial experience. Int J Cardiovasc Imaging 34, 293–300 (2018). https://doi.org/10.1007/s10554-017-1223-y

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10554-017-1223-y

Keywords

Navigation