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Nephrotic syndrome and IgA nephropathy in polycystic kidney disease

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Abstract

A 70-year-old man with polycystic kidney disease developed nephrotic syndrome, deteriorating to renal insufficiency. Histological examination revealed IgA nephropathy. With treatment of prednisolone, an angiotensin-converting enzyme inhibitor, and an angiotensin II receptor-blocker, his proteinuria markedly decreased and renal function was stabilized. This case supports the idea that renal biopsy is needed in patients with polycystic kidney disease with nephrotic-range proteinuria, for appropriate treatment and prevention of renal failure.

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Authors and Affiliations

  1. Department of Internal Medicine, Nagaoka Red Cross Hospital, 297-1 Terajima-machi, Nagaoka, Niigata, 940-2085, Japan

    Toru Hiura, Hajime Yamazaki, Takako Saeki, Shotetsu Kawabe & Shoji Miyamura

  2. Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medicine, Niigata, Japan

    Toru Hiura, Shotetsu Kawabe, Mitsuhiro Ueno, Shinichi Nishi & Fumitake Gejyo

Authors
  1. Toru Hiura
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  2. Hajime Yamazaki
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  3. Takako Saeki
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  4. Shotetsu Kawabe
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  5. Mitsuhiro Ueno
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  6. Shinichi Nishi
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  7. Shoji Miyamura
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  8. Fumitake Gejyo
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Correspondence to Hajime Yamazaki.

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Hiura, T., Yamazaki, H., Saeki, T. et al. Nephrotic syndrome and IgA nephropathy in polycystic kidney disease. Clin Exp Nephrol 10, 136–139 (2006). https://doi.org/10.1007/s10157-005-0403-6

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  • DOI: https://doi.org/10.1007/s10157-005-0403-6

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