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Treatment outcomes of micropulse transscleral cyclophotocoagulation in advanced glaucoma

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Abstract

Glaucoma is the leading cause of irreversible blindness worldwide. The goal of this study was to describe our experience with the novel micropulse transscleral cyclophotocoagulation (MP-TSCPC; IRIDEX IQ810 Laser Systems, CA) in patients with advanced glaucoma. Patients with advanced glaucoma who underwent MP-TSCPC were included in our study. Laser settings were 2000 mW of 810 nm infrared diode laser set on micropulse delivery mode. The laser was delivered over 360° for 100–240 s. The duty cycle was 31.3 %, which translated to 0.5 ms of “on time” and 1.1 ms of “off time.” Surgical success was defined as an intraocular pressure (IOP) of 6–21 mmHg or a reduction of IOP by 20 % at the last follow-up visit. Failure was defined as an inability to meet the criteria for success or a need for incisional glaucoma surgery. Nineteen patients underwent MP-TSCPC with mean follow-up of 60.3 days. Mean IOP dropped from 37.9 mmHg preoperatively to 22.7 mmHg at last follow-up, representing a 40.1 % decrease. The success rate for initial treatment was 73.7 % (n = 14). Three patients underwent a second treatment, increasing the overall success rate to 89.5 % (n = 17). Four patients gained one line of vision, and four patients lost one line of vision. The novel MP-TSCPC laser had a high rate of surgical success after a short follow-up period in patients with advanced glaucoma. Further long-term evaluation and comparison to the traditional transscleral cyclophotocoagulation are warranted.

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Authors and Affiliations

  1. Glaucoma Research Center, Wills Eye Hospital, Philadelphia, PA, 19107, USA

    Sarah Kuchar, Marlene R. Moster, Courtney B. Reamer & Michael Waisbourd

Authors
  1. Sarah Kuchar
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  2. Marlene R. Moster
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  3. Courtney B. Reamer
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  4. Michael Waisbourd
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Corresponding author

Correspondence to Michael Waisbourd.

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Funding

Iridex Corporation provided the laser platform used in this study.

Ethical approval

All procedures performed in studies involving human participants were conducted in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. For this type of study (retrospective chart review), formal consent is not required.

Conflict of interest

Drs. Moster, Kuchar, and Waisbourd received research support from Iridex. Dr. Moster is a consultant for Alcon, Allergan, Solx, and Merck; was an expert testimony case witness in 2013; has grants from Aerie, Aeon, New World Medical, Alcon, Glaukos, and Bausch and Lomb; and receives payment for lectures from Alcon, Allergan, Ista, Merck, Bausch and Lomb, New World Medical, TBI, and Solx. Courtney Reamer has no conflicts of interest to declare.

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Kuchar, S., Moster, M.R., Reamer, C.B. et al. Treatment outcomes of micropulse transscleral cyclophotocoagulation in advanced glaucoma. Lasers Med Sci 31, 393–396 (2016). https://doi.org/10.1007/s10103-015-1856-9

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  • DOI: https://doi.org/10.1007/s10103-015-1856-9

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