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Evaluating the optic nerve stiffness and optic nerve sheath diameter in idiopathic intracranial hypertension patients after the resolution of papilledema

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Abstract

Purpose

The objective of this study was to investigate the optic nerve’s elastic properties and optic nerve sheath diameter (ONSD) using shear-wave elastography (SWE) in patients with idiopathic intracranial hypertension (IIH) compared to healthy individuals.

Methods

The study included 22 IIH patients and 15 healthy subjects. SWEs were performed on the optic nerve and ONSD, and optic nerve stiffness were measured.

Results

The patients with IIH demonstrated higher stiffness of the optic nerve compared with that of healthy volunteers (P < 0.001). The optic nerve sheath diameter of the optic nerve in the IIH group was significantly larger than that in the control group (P < 0.001). There was no correlation between the disease duration and SWE values in the Spearman correlation test.

Conclusion

These findings suggest that ONSD can be used as a follow-up method in the treatment of IIH. However, there was not any correlation between the disease duration and SWE-based stiffness measurement of the optic nerve.

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Abbreviations

IIH:

Idiopathic intracranial hypertension

SWE:

Shear-wave elastography

ONSD:

Optic nerve sheath diameter

ICP:

Intracranial pressure

US:

Ultrasonography

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Authors and Affiliations

  1. Ophthalmology Department, Çam and Sakura City Hospital, Başakşehir Olimpiyat Bulvarı Yolu, 34480, Başakşehir, İstanbul, Turkey

    Fatma Selin Kaya

  2. Radiology Department, Bakirkoy Dr Sadi Konuk Training and Research Hospital, Bakirkoy, İstanbul, Turkey

    Ersoy Bayram & Ercan İnci

Authors
  1. Fatma Selin Kaya
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  2. Ersoy Bayram
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  3. Ercan İnci
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Correspondence to Fatma Selin Kaya.

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The authors declare no competing interests.

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The study was performed according to the ethical standards laid down in the 1964 Helsinki Declaration and its later amendments. Written informed consent was obtained from the participants.

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Kaya, F.S., Bayram, E. & İnci, E. Evaluating the optic nerve stiffness and optic nerve sheath diameter in idiopathic intracranial hypertension patients after the resolution of papilledema. Neurol Sci 42, 5165–5170 (2021). https://doi.org/10.1007/s10072-021-05208-z

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  • DOI: https://doi.org/10.1007/s10072-021-05208-z

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