Skip to main content
Log in

Surgical planning, manufacturing and implantation of an individualized cervical fusion titanium cage using patient-specific data

  • Ideas and Technical Innovations
  • Published:
European Spine Journal Aims and scope Submit manuscript

Abstract

Background

Most cervical fusion cages imperfectly mimic the anatomy of the intervertebral disc space. The production of individualized cages might be the next step to further improve spinal implants due to their enhanced load-bearing surface.

Objective

To evaluate the planning, manufacturing, and implantation of an individualized cervical cage in co-operation with EIT and 3D Systems.

Methods

A digital 3D model of the patient’s cervical spine was rendered from the patients CT data. It was then possible to correct degenerative deformities by digitally repositioning the vertebrae and virtually resecting the osteophytes. The implantation of the cage can be simulated to check the accuracy of the fit. The cage is made of trabecular titanium and manufactured by Direct Metal Printing.

Results

The pilot project for the implantation of the first individualized cervical cage ever, resulted in a highly accurate fit. During surgery, the cage self-located into the correct position after suspending distraction due to the implants unique end plate design. Furthermore, it was impossible to move the cage in any direction with the inserting instrument after suspending distraction for the same reason. Thus, it can be assumed that an individualized cervical implant provides excellent primary stability.

Conclusion

Preconditions for the manufacturing of individualized cervical fusion cages using specific patient data are given. The implantation is uncomplicated. The improved load-bearing surface will lower the rate of implant dislocation and subsidence. The production of individualized cages at a reasonable price has to be evaluated by spine surgeons and the industry.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8

Similar content being viewed by others

References

  1. Yamagata T, Takami T, Uda T, Ikeda H, Nagata T, Sakamoto S, Tsuyuguchi N, Ohata K (2012) Outcomes of contemporary use of rectangular titanium stand-alone cages in anterior cervical discectomy and fusion: cage subsidence and cervical alignment. J Clin Neurosci 19(12):1673–1678

    Article  PubMed  Google Scholar 

  2. Cabraja M, Oezdemir S, Koeppen D, Kroppenstedt S (2012) Anterior cervical discectomy and fusion: comparison of titanium and polyetheretherketone cages. BMC Musculoskelet Disord 13:172

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Wu WJ, Jiang LS, Liang Y, Dai LY (2012) Cage subsidence does not, but cervical lordosis improvement does affect the long-term results of anterior cervical fusion with stand-alone cage for degenerative cervical disc disease: a retrospective study. Eur Spine J 21(7):1374–1382

    Article  PubMed  Google Scholar 

  4. Kolstad F, Nygaard ØP, Andresen H, Leivseth G (2010) Anterior cervical arthrodesis using a “stand alone” cylindric titanium cage: prospective analysis of radiographic parameters. Spine (Phila Pa 1976) 35(16):1545–1550

    Article  Google Scholar 

  5. Aitasalo KM, Piitulainen JM, Rekola J, Vallittu PK (2014) Craniofacial bone reconstruction with bioactive fiber-reinforced composite implant. Head Neck 36(5):722–728

    Article  PubMed  Google Scholar 

  6. Rotaru H, Stan H, Florian IS, Schumacher R, Park YT, Kim SG, Chezan H, Balc N, Baciut M (2012) Cranioplasty with custom-made implants: analyzing the cases of 10 patients. J Oral Maxillofac Surg 70(2):e169–e176

    Article  PubMed  Google Scholar 

  7. Cabraja M, Klein M, Lehmann TN (2009) Long-term results following titanium cranioplasty of large skull defects. Neurosurg Focus 26(6):E10

    Article  PubMed  Google Scholar 

  8. Origitano TC, Izquierdo R, Scannicchio LB (1995) Reconstructing complex cranial defects with a preformed cranial prosthesis. Skull Base Surg 5(2):109–116

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. Skeppholm M, Svedmark P, Noz ME, Maguire GQ Jr, Olivecrona H, Olerud C (2015) Evaluation of mobility and stability in the Discover artificial disc: an in vivo motion study using high-accuracy 3D CT data. J Neurosurg Spine 23(3):383–389

    Article  PubMed  Google Scholar 

  10. Lee CH, Kim KJ, Hyun SJ, Yeom JS, Jahng TA, Kim HJ (2015) Subsidence as of 12 months after single-level anterior cervical inter-body fusion. Is it related to clinical outcomes? Acta Neurochir (Wien) 157(6):1063–1068

    Article  Google Scholar 

  11. Brenke C, Dostal M, Scharf J, Weiß C, Schmieder K, Barth M (2014) Influence of cervical bone mineral density on cage subsidence in patients following stand-alone anterior cervical discectomy and fusion. Eur Spine J. doi:10.1007/s00586-014-3725-9

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Stefan Alexander König.

Ethics declarations

Conflict of interest

The authors have no personal financial or institutional interest in any of the materials, or devices described in this article.

Electronic supplementary material

Below is the link to the electronic supplementary material.

Supplementary material 1 (MP4 342865 kb)

Supplementary material 2 (DOCX 11 kb)

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Spetzger, U., Frasca, M. & König, S.A. Surgical planning, manufacturing and implantation of an individualized cervical fusion titanium cage using patient-specific data. Eur Spine J 25, 2239–2246 (2016). https://doi.org/10.1007/s00586-016-4473-9

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00586-016-4473-9

Keywords

Navigation