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Safety, efficacy, and patient-perceived satisfaction of peripherally inserted central catheters in terminally ill cancer patients: a prospective multicenter observational study

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Abstract

Purpose

The purpose of this study was to investigate the safety, efficacy, and subjective satisfaction of peripherally inserted central catheters (PICCs) in terminally ill cancer patients.

Methods

All PICCs were inserted by an interventional radiologist with radiological guidance. We monitored the occurrence of PICC-related complication and evaluated the patient-perceived satisfaction for PICC using semi-structured questionnaire.

Results

A total of 36 terminally ill cancer patients underwent PICC. Three patients had 2 PICC insertions; hence, finally 39 episodes during 829 PICC days were analyzed. All procedures were completed without any procedure-related complication. The median catheter life span was 19.0 days (95 % CI, 14.1–23.9). Thirty-four cases maintained the PICC until the intended time, while the other 5 cases (12.8 %; 6.1/1000 PICC days) were premature PICC removals. Totally 10 complications (25.6 %; 12.3/1000 PICC days) were reported including premature removals (n = 5), trivial bleedings (n = 3), and thrombophlebitis (n = 2). Patients reported that the procedure was not distressing (42 %), a little distressing (36 %), or distressing (21 %). Of 30 patients who had preserved cognitive function at fifth day, most patients (n = 25, 83 %) reported more comfort although the other 5 patients reported no change (n = 3) or less comfort (n = 2).

Conclusions

PICCs were safely inserted and showed favorable maintenance rate with acceptable complications. Additionally, most of the patients felt that parenteral access became much comfortable after PICC insertion. When considering the characteristics of terminally ill cancer patients, poor general condition and a limited period of survival, PICC could be a safe and effective method for intravenous access.

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References

  1. Cleeland CS (2000) Cancer-related symptoms. Semin Radiat Oncol 10(3):175–190

    Article  CAS  PubMed  Google Scholar 

  2. Mercadante S, Ferrera P, Girelli D, Casuccio A (2005) Patients’ and relatives’ perceptions about intravenous and subcutaneous hydration. J Pain Symptom Manag 30(4):354–358. doi:10.1016/j.jpainsymman.2005.04.004

    Article  Google Scholar 

  3. Walshe LJ, Malak SF, Eagan J, Sepkowitz KA (2002) Complication rates among cancer patients with peripherally inserted central catheters. J Clin Oncol Off J Am Soc Clin Oncol 20(15):3276–3281

    Article  Google Scholar 

  4. Ng PK, Ault MJ, Ellrodt AG, Maldonado L (1997) Peripherally inserted central catheters in general medicine. Mayo Clin Proc 72(3):225–233. doi:10.1016/s0025-6196(11)64753-8

    Article  CAS  PubMed  Google Scholar 

  5. Smith JR, Friedell ML, Cheatham ML, Martin SP, Cohen MJ, Horowitz JD (1998) Peripherally inserted central catheters revisited. Am J Surg 176(2):208–211

    Article  CAS  PubMed  Google Scholar 

  6. Gunst M, Matsushima K, Vanek S, Gunst R, Shafi S, Frankel H (2011) Peripherally inserted central catheters may lower the incidence of catheter-related blood stream infections in patients in surgical intensive care units. Surg Infect 12(4):279–282. doi:10.1089/sur.2008.058

    Article  Google Scholar 

  7. Kim HJ, Yun J, Kim HJ, Kim KH, Kim SH, Lee SC, Bae SB, Kim CK, Lee NS, Lee KT, Park SK, Won JH, Park HS, Hong DS (2010) Safety and effectiveness of central venous catheterization in patients with cancer: prospective observational study. J Korean Med Sci 25(12):1748–1753. doi:10.3346/jkms.2010.25.12.1748

    Article  PubMed  PubMed Central  Google Scholar 

  8. Park K, Lim HG, Hong JY, Song H (2014) Safety and efficacy of peripherally inserted central catheters in terminally ill cancer patients: single institute experience. Korean J Hosp Palliat Care 17(3):179–184

    Article  Google Scholar 

  9. Morita T, Tei Y, Tsunoda J, Inoue S, Chihara S (2001) Underlying pathologies and their associations with clinical features in terminal delirium of cancer patients. J Pain Symptom Manag 22(6):997–1006

    Article  CAS  Google Scholar 

  10. Lundh Hagelin C, Seiger A, Furst CJ (2006) Quality of life in terminal care--with special reference to age, gender and marital status. Support Care Cancer : Off J Multinational Assoc Support Care Cancer 14(4):320–328. doi:10.1007/s00520-005-0886-4

    Article  CAS  Google Scholar 

  11. Lee GJ, Ahn HS, Go SE, Kim JH, Seo MW, Kang SH, Yang YR, Lee MY, Lee KO, Chun SH, Jin JY (2015) Patient’s factors at entering hospice affecting length of survival in a hospice center. Cancer Res Treatment : Off J Korean Cancer Assoc 47(1):1–8. doi:10.4143/crt.2013.148

    Article  CAS  Google Scholar 

  12. Llobera J, Esteva M, Rifa J, Benito E, Terrasa J, Rojas C, Pons O, Catalan G, Avella A (2000) Terminal cancer. Duration and prediction of survival time. Eur J Cancer (Oxford, England : 1990) 36(16):2036–2043

    Article  CAS  Google Scholar 

  13. Yamada R, Morita T, Yashiro E, Otani H, Amano K, Tei Y, Inoue S (2010) Patient-reported usefulness of peripherally inserted central venous catheters in terminally ill cancer patients. J Pain Symptom Manag 40(1):60–66. doi:10.1016/j.jpainsymman.2009.11.327

    Article  Google Scholar 

  14. Sansivero GE (2000) The microintroducer technique for peripherally inserted central catheter placement. Journal of intravenous nursing : the official publication of the intravenous nurses society 23 (6):345–351

  15. McGee DC, Gould MK (2003) Preventing complications of central venous catheterization. N Engl J Med 348(12):1123–1133. doi:10.1056/NEJMra011883

    Article  PubMed  Google Scholar 

  16. Li J, Fan YY, Xin MZ, Yan J, Hu W, Huang WH, Lin XL, Qin HY (2014) A randomised, controlled trial comparing the long-term effects of peripherally inserted central catheter placement in chemotherapy patients using B-mode ultrasound with modified Seldinger technique versus blind puncture. Eur J Oncol Nurs 18(1):94–103. doi:10.1016/j.ejon.2013.08.003

    Article  PubMed  Google Scholar 

  17. Yap YS, Karapetis C, Lerose S, Iyer S, Koczwara B (2006) Reducing the risk of peripherally inserted central catheter line complications in the oncology setting. Eur J Cancer Care 15(4):342–347. doi:10.1111/j.1365-2354.2006.00664.x

    Article  Google Scholar 

  18. Cheong K, Perry D, Karapetis C, Koczwara B (2004) High rate of complications associated with peripherally inserted central venous catheters in patients with solid tumours. Intern Med J 34(5):234–238. doi:10.1111/j.1444-0903.2004.00447.x

    Article  CAS  PubMed  Google Scholar 

  19. Mermel LA (2000) Prevention of intravascular catheter-related infections. Ann Intern Med 132(5):391–402

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Hematology-Oncology, KEPCO Medical Center, Seoul, South Korea

    Kwonoh Park

  2. Medical Oncology and Hematology, Department of Internal Medicine, Pusan National University Yangsan Hospital, 20, Geumo-ro, Mulgeum-eup, Yangsan-si, Gyeongsangnam-do, South Korea

    Kwonoh Park & So Yeon Oh

  3. Department of Internal medicine, Seoul Medical Center, Seoul, South Korea

    Hyun Jung Jun

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  1. Kwonoh Park
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  2. Hyun Jung Jun
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Correspondence to So Yeon Oh.

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The authors declare that they have no conflict of interest.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

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Park, K., Jun, H.J. & Oh, S.Y. Safety, efficacy, and patient-perceived satisfaction of peripherally inserted central catheters in terminally ill cancer patients: a prospective multicenter observational study. Support Care Cancer 24, 4987–4992 (2016). https://doi.org/10.1007/s00520-016-3360-6

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  • DOI: https://doi.org/10.1007/s00520-016-3360-6

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