Abstract
The first case of well-differentiated intrahepatic cholangiocarcinoma with remarkable follicular architecture resembling a follicular neoplasm of thyroid is described in a 52-year-old man. The follicles contained homogenous eosinophilic material akin to colloid and were lined by benign-looking cuboidal cells. Immunohistochemically, thyroid transcription factor-1 (TTF-1) and thyroglobulin were negative and the patient had no evidence of a previous or concomitant thyroid tumour. This case can be added to the list of extrathyroid primary tumours that resemble thyroid neoplasms.
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Acknowledgments
Professor Juan Rosai is thanked for having reviewed the case.
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We declare that we have no conflict of interest.
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Fornelli, A., Bondi, A., Jovine, E. et al. Intrahepatic cholangiocarcinoma resembling a thyroid follicular neoplasm. Virchows Arch 456, 339–342 (2010). https://doi.org/10.1007/s00428-009-0874-z
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DOI: https://doi.org/10.1007/s00428-009-0874-z