Skip to main content
SpringerLink
Log in

Propofol-induced coved-type electrocardiogram during catheter ablation of paroxysmal atrial fibrillation

A case of Brugada syndrome?

Propofol-induzierte coved-type ST-Streckenhebung während Katheterablation von paroxysmalem Vorhofflimmern

Ein Fall von Brugada-Syndrom?

  • Case Report
  • Published:
Herzschrittmachertherapie + Elektrophysiologie Aims and scope Submit manuscript

Abstract

We report a case of a young man with paroxysmal atrial fibrillation, in whom a characteristic coved-type Brugada pattern developed during catheter ablation performed under sedation with propofol. After immediate discontinuation of the propofol infusion, coved-type ST-segment elevation gradually resolved and no ventricular arrhythmias occurred. An ajmaline challenge failed to unmask a coved-type electrocardiogram and genetic testing was negative for ion channel mutations related to Brugada syndrome.

Zusammenfassung

Vorgestellt wird ein junger Patient mit paroxysmalem Vorhofflimmern, bei dem sich während der Katheterablation unter Propofol-Sedierung die für das Brugada-Syndrom charakteristische coved-type ST-Streckenhebung entwickelte. Nach sofortigem Abbruch der Propofol-Infusion bildete sich diese EKG-Veränderung allmählich zurück, und es traten keine ventrikulären Arrhythmien auf. Nach Ajmalin-Provokation kam es nicht zur Demaskierung einer coved-type ST-Streckenhebung, und die Genuntersuchung zeigte keine Ionenkanalmutationen mit Assoziation zum Brugada-Syndrom.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

References

  1. Junttila MJ, Gonzalez M, Lizotte E et al (2008) Induced Brugada-type electrocardiogram, a sign for imminent malignant arrhythmias. Circulation 117:1890–1893

    Article  PubMed  Google Scholar 

  2. Vernooy K, Delhaas T, Cremer OL et al (2006) Electrocardiographic changes predicting sudden death in propofol-related infusion syndrome. Heart Rhythm 3:131–137

    Article  PubMed  Google Scholar 

  3. Pappone C, Radinovic A, Manguso F et al (2009) New-onset atrial fibrillation as first clinical manifestation of latent Brugada syndrome: prevalence and clinical significance. Eur Heart J 30:2985–2992

    Article  PubMed  Google Scholar 

Download references

Conflict of interest

The corresponding author states that there are no conflicts of interest.

Author information

Authors and Affiliations

  1. Department of Electrophysiology, Heart Center, University of Leipzig, Strümpellstr. 39, 04289, Leipzig, Germany

    S. Richter MD

  2. The Heart Rhythm Management Centre, Cardiovascular Centre, Free University of Brussels (UZ Brussel), Brussels, Belgium

    P. Brugada MD, PhD

Authors
  1. S. Richter MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. P. Brugada MD, PhD
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to S. Richter MD.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Richter, S., Brugada, P. Propofol-induced coved-type electrocardiogram during catheter ablation of paroxysmal atrial fibrillation. Herzschr. Elektrophys. 23, 56–58 (2012). https://doi.org/10.1007/s00399-011-0156-8

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00399-011-0156-8

Keywords

Schlüsselwörter

Search

Navigation