Abstract
We herein describe a 4-year-old boy who after being treated for pneumonia showed an abnormal shadow at the hilus of the right lung on chest X-rays with continued inflammatory findings in his laboratory data. CT and MR investigations suggested the existence of a neoplasm at that site. An open biopsy was thus performed for a definite diagnosis. The histological findings and the expression of TPM3–ALK fusion gene confirmed a diagnosis of an inflammatory myofibroblastic tumor. A right upper and middle lobectomy including the tumor was thus performed for a complete resection. In addition to the histological diagnosis, the detection of the tumor specific fusion gene provided objective evidence in making a diagnosis.
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Kinoshita, Y., Tajiri, T., Ieiri, S. et al. A case of an inflammatory myofibroblastic tumor in the lung which expressed TPM3–ALK gene fusion. Pediatr Surg Int 23, 595–599 (2007). https://doi.org/10.1007/s00383-006-1821-6
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DOI: https://doi.org/10.1007/s00383-006-1821-6