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Soft-tissue tumors update: MR imaging features according to the WHO classification

  • Musculoskeletal
  • Published:
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Abstract

Soft-tissue tumors are a large and heterogeneous group of neoplasms. Hence, classification is often difficult. The most effective management decisions are made when a working group participates in the same diagnostic standard criteria in the evaluation of soft-tissue tumors. The purpose of this pictorial review is to highlight the new and the less well-known features on magnetic resonance (MR) imaging of soft-tissue tumors according to the World Health Organization (WHO) classification established in 2002. The article depicts the major changes of the WHO classification since it was established in 2002 and the most significant findings on MR imaging, thereby providing an update.

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References

  1. Fletcher CDM, Unni KK, Mertens F (2002) Pathology and genetics of tumours of soft tissue and bone. In: World Health Organization Classification of Tumours, IARC Press, Lyon

  2. Leonhardt J, Schirg E, Schmidt H, Gluer S (2004) Imaging characteristics of childhood lipoblastoma. Fortschr Rontgenstr 176:972–975

    Article  CAS  Google Scholar 

  3. Murphey MD, Carroll JF, Flemming DJ, Pope TL, Gannon FH, Kransdorf MD (2004) Benign musculoskeletal lipomatous lesions. Radiographics 24:1433–1466

    Article  PubMed  Google Scholar 

  4. Green RA, Cannon SR, Flannagan AM (2004) Chondroid lipoma: correlation of imaging findings and histopathology of an unusual benign lesion. Skeletal Radiol 33:670–673

    Article  PubMed  CAS  Google Scholar 

  5. Bancroft LW, Kransdorf MJ, Peterson JJ, Sundaram M, Murphey MD, O’Connor MI (2003) Imaging characteristics of spindle cell lipoma. AJR Am J Roentgenol 181:1251–1254

    PubMed  Google Scholar 

  6. Anderson SE, Schwab C, Stauffer E, Banic A, Steinbach LS (2001) Hibernoma: imaging characteristics of a rare benign soft tissue tumor. Skeletal Radiol 30:590–595

    Article  PubMed  CAS  Google Scholar 

  7. Kransdorf MJ, Bancroft LW, Peterson JJ, Murphey MD, Foster WC, Temple HT (2002) Imaging of fatty tumors: distinction of lipoma and well-differentiated liposarcoma. Radiology 224:99–104

    Article  PubMed  Google Scholar 

  8. Galant J, Marti-Bonmati L, Saez F, Soler R, Alcala-Santaella R, Navarro M (2003) The value of fat-suppressed T2 or STIR sequences in distinguishing lipoma from well-differentiated liposarcoma. Eur Radiol 13:337–343

    PubMed  CAS  Google Scholar 

  9. Ohguri T, Aoki T, Hisaoka M et al (2003) Differential diagnosis of peripheral lipoma from well-differentiated liposarcoma on MR imaging: is comparison of margins and internal characteristics useful? AJR Am J Roentgenol 180:1689–1694

    PubMed  Google Scholar 

  10. Sung MS, Kang HS, Suh JS, Lee JH, Park JM, Kim JY, Lee HG (2000) Myxoid liposarcoma: appearance at MR imaging with histologic correlation. Radiographics 20:1007–1019

    PubMed  CAS  Google Scholar 

  11. Wang XL, De Schepper AM, Vanhoenacker F, De Raeve H, Gielen J, Aparisi F, Rausin L, Somville J (2002) Nodular fasciitis: correlation of MRI findings and histopathology. Skeletal Radiol 31:155–1613

    Article  PubMed  CAS  Google Scholar 

  12. De Smet AA, Norris MA, Fisher DR (1992) Magnetic resonance imaging of myositis ossificans: analysis of seven cases. Skeletal Radiol 21:503–507

    PubMed  Google Scholar 

  13. Naylor MF, Nascimento AG, Sherrick AD, McLeod RA (1996) Elastofibroma dorsi: radiologic findings in 12 patients. AJR Am J Roentgenol 167:683–687

    PubMed  CAS  Google Scholar 

  14. Koujok K, Ruiz RE, Hernandez RJ (2005) Myofibromatosis: imaging characteristics. Pediatr Radiol 35:374–380

    Article  PubMed  Google Scholar 

  15. Fox MG, Kransdorf MJ, Bancroft LW, Peterson JJ, Flemming DJ (2003) MR imaging of fibroma of the tendon sheath. AJR Am J Roentgenol 180:1449–1453

    PubMed  Google Scholar 

  16. Robbin MR, Murphey MD, Temple T, Kransdorf MJ, Choi JJ (2001) Imaging of musculoskeletal fibromatosis. Radiographics 21:585–600

    PubMed  CAS  Google Scholar 

  17. Yacoe ME, Bergman AG, Ladd AL, Hellman BH (1993) Dupuytren’s contracture: MR imaging findings and correlation between MR signal intensity and cellularity of lesions. AJR Am J Roentgenol 160:813–817

    PubMed  CAS  Google Scholar 

  18. Morrison WB, Schweitzer ME, Wapner KL, Lackman RD (1994) Plantar fibromatosis: a benign neoplasm with a characteristic appearance on MR images. Radiology 193:841–845

    PubMed  CAS  Google Scholar 

  19. Vandevenne JE, De Schepper AM, De Beuckeleer L, Van Marck E, Aparisi F, Bloem JL, Erkorkmaz Z, Brijs S (1997) New concepts in understanding evolution of desmoid tumors: MR imaging of 30 lesions. Eur Radiol 7:1013–1019

    Article  PubMed  CAS  Google Scholar 

  20. Murphey MD, Fairbairn KJ, Parman LM, Baxter KG, Parsa MB, Smith ES (1995) Musculoskeletal angiomatous lesions: radiologic-pathologic correlation. Radiographics 15:893–917

    PubMed  CAS  Google Scholar 

  21. Waldt S, Rechl H, Rummeny EJ, Woertler K (2003) Imaging of benign and malignant soft tissue masses of the foot. Eur Radiol 13:1125–1136

    PubMed  Google Scholar 

  22. Dodd LG, Major N, Brigman B (2004) Malignant giant cell tumor of soft parts. Skeletal Radiol 33:295–299

    Article  PubMed  Google Scholar 

  23. Rosenberg AE (2003) Malignant fibrous histiocytoma: past, present, and future. Skeletal Radiol 32:613–619

    Article  PubMed  CAS  Google Scholar 

  24. Hwang JW, Ahn JM, Kang HS et al (1998) Vascular leiomyoma of an extremity: MR imaging-pathology correlation. AJR Am J Roentgenol 171:981–985

    PubMed  CAS  Google Scholar 

  25. Kugimoto Y, Asami A, Shigematsu M, Hotokebuchi T (2004) Giant vascular leiomyoma with extensive calcification in the forearm. J Orthop Sci 9:310–313

    Article  PubMed  Google Scholar 

  26. Misumi S, Irie T, Fukuda K, Tada S, Hosomura Y (2000) A case of deep soft tissue leiomyoma: CT and MRI findings. Radiat Med 18:253–256

    PubMed  CAS  Google Scholar 

  27. Watson GM, Saifuddin A, Sandison A (1999) Deep soft tissue leiomyoma of the thigh. Skeletal Radiol 28:411–414

    Article  PubMed  CAS  Google Scholar 

  28. Miyazaki T, Tamura S, Sugimura H et al (1993) Retroperitoneal leiomyosarcoma. Its MR manifestations. Clin Imaging 17:207–209

    Article  PubMed  CAS  Google Scholar 

  29. Killoran TP, Wells WA, Barth RJ, Goodwin DW (2003) Leiomyosarcoma of the popliteal vein. Skeletal Radiol 32:174–178

    Article  PubMed  Google Scholar 

  30. Vilanova JC, Barceló J, Smirniotopoulos JG et al (2004) Hemangioma from head to toe: MR imaging with pathologic correlation. Radiographics 24:367–385

    Article  PubMed  Google Scholar 

  31. Van Ruyssevelt CE, Vranckx P (2004) Subungual glomus tumor: enphasis on MR angiography. AJR Am J Roentgenol 182:263–264

    PubMed  Google Scholar 

  32. Liang GS, Loevner LA, Kumar P (2000) Laryngeal rhabdomyoma involving the paraglottic space. AJR Am J Roentgenol 174:1285–1287

    PubMed  CAS  Google Scholar 

  33. McCarville MB, Spunt SL, Pappo AS (2001) Rhabdomyosarcoma in pediatric patients: the good, the bad, and the unusual. AJR Am J Roentgenol 176:1563–1569

    PubMed  CAS  Google Scholar 

  34. Vilanova JC, Barceló J, Villalón M (2004) MR and MR Angiography characterization of soft tissue vascular malformations. Curr Probl Diagn Radiol 33:161–170

    Article  PubMed  Google Scholar 

  35. Nakazono T, Kudo S, Matsuo Y (2000) Angiosarcoma associated with chronic lymphedema (Stewart-Treves syndrome) of the leg: MR imaging. Skeletal Radiol 29:413–416

    Article  PubMed  CAS  Google Scholar 

  36. Horcajadas AB, Lafuente JL, de la Cruz Burgos R et al (2003) Ultrasound and MR findings in tumor and tumor-like lesions of the fingers. Eur Radiol 13:672–685

    PubMed  Google Scholar 

  37. De Schepper AM (ed) (2001) Imaging of soft tissue tumors, 2nd edn. Springer, Berlin Heidelberg New York

    Google Scholar 

  38. Murphey MD, Smith WS, Smith SE, Kransdorf MJ, Temple HT (1999) Imaging of musculoskeletal neurogenic tumors: radiologic-pathologic correlation. Radiographics 19:1253–1280

    PubMed  CAS  Google Scholar 

  39. Bhargava R, Parham DM, Lasater OE et al (1997) MR imaging differentiation of benign and malignant peripheral nerve sheath tumors: use of the target sign. Pediatr Radiol 27:124–129

    Article  PubMed  CAS  Google Scholar 

  40. Luna A, Martínez S, Bossen (2005) Magnetic resonance imaging of intramuscular myxoma with histological comparison and a review of the literature. Skeletal Radiol 34:19–28

    Article  PubMed  CAS  Google Scholar 

  41. Stewart ST, McCarthy SM (2004) Case 77: aggressive angiomyxoma. Radiology 233:697–700

    Article  PubMed  Google Scholar 

  42. Schaffler G, Raith J, Ranner G, Weybora W, Jeserschek R (1997) Radiographic appearance of an ossifying fibromyxoid tumor of soft parts. Skeletal Radiol 26:615–618

    Article  PubMed  CAS  Google Scholar 

  43. Narvaez JA, Narvaez J, Aguilera C, De Lama E, Portabella F (2001) MR imaging of synovial tumors and tumor-like lesions. Eur Radiol 11:2549–2560

    Article  PubMed  CAS  Google Scholar 

  44. Chao KC, Chen C, Hsieh SC, Fang CL, Lao WT, Chan WP (2005) MRI of epithelioid sarcoma of the thigh. Clin Imaging 29:60–63

    Article  PubMed  Google Scholar 

  45. Suh JS, Cho J, Lee SH et al (2000) Alveolar soft part sarcoma: MR and angiographic findings. Skeletal Radiol 29:680–689

    Article  PubMed  CAS  Google Scholar 

  46. Harimaya K, Oda Y, Matsuda S, Tanaka K, Chuman H, Iwamoto Y (2003) Primitive neuroectodermal tumor and extraskeletal Ewing sarcoma arising primarily around the spinal column: report of four cases and a review of the literature. Spine 28:E408–E412

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Magnetic Resonance, Clínica Girona, Lorenzana, 36, 17002, Girona, Spain

    Joan C. Vilanova, Joaquim Barceló & Miguel Villalón

  2. Department of Radiology, Technische Universität Munich, Munich, Germany

    Klaus Woertler

  3. Department of Radiology, Hospital Universitari de Bellvitge - IDI. Hospitalet de Llobregat, Barcelona, Spain

    José A. Narváez

  4. Department of Radiology, Duke University Medical Center, Durham, North Carolina, USA

    Salutario J. Martínez

  5. Department of Pathology, Clínica Girona, Girona, Spain

    Josefina Miró

Authors
  1. Joan C. Vilanova
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  2. Klaus Woertler
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  3. José A. Narváez
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  4. Joaquim Barceló
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  5. Salutario J. Martínez
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  6. Miguel Villalón
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  7. Josefina Miró
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Correspondence to Joan C. Vilanova.

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Vilanova, J.C., Woertler, K., Narváez, J.A. et al. Soft-tissue tumors update: MR imaging features according to the WHO classification. Eur Radiol 17, 125–138 (2007). https://doi.org/10.1007/s00330-005-0130-0

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  • DOI: https://doi.org/10.1007/s00330-005-0130-0

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