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Percutaneous vertebroplasty immediately relieves pain of osteoporotic vertebral compression fractures and prevents prolonged immobilization of patients

  • Musculoskeletal
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Abstract

To assess the immediate efficacy of percutaneous vertebroplasty (PVP) in relief of pain and improving mobility of patients with vertebral compression fractures (VCF) secondary to osteoporosis, 205 cases (175 patients) underwent 250 percutaneous injections of polymethylmethacrylate (PMMA; unilateral, 247 levels; bilateral, 3 levels) into vertebrae under CT and fluoroscopic guidance for 34 months. Patients were prospectively asked to quantify their pain on a visual analog scale (VAS) before and a day after PVP. The interval to mobilization was recorded in those who were immobilized because of pain and/or bed-rest therapy (115 cases). PVP was technically successful in all patients, with three cases of minimal complications. The mean VAS score available for 196 cases was improved from 7.22±1.89 (range, 3–10) to 2.07±1.19 (range, 0–10) by PVP. Ninety-four of 115 immobilized cases (81.7%) were mobile by 24 h after PVP, and the mean value was 1.9±2.8 days. The incidence of recurrent and new fractures was 15.6% in 4–25 months (mean, 15.3 months). PVP is a safe and effective treatment for relieving the pain associated with osteoporotic VCF and strengthening the vertebrae, avoiding refractures. This therapy leads to early mobilization and avoidance of the dangers of conservative therapy of bed-rest.

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Acknowledgments

The authors thank Masato Fujiwara, MD; Susumu Sasaki, MD; Nobuaki Kawaraya, MD; Yasuhiro Shigaki, MD; Akitsugu Nishiyama, MD; Osamu Shiroeda, MD; Hiroko Ujigawa, MD; Tetsumi Nakagawa, RT; Keiji Imai, RT; Satoshi Kandani, RT; and Kasumi Akai, RN for their collaboration and support in this study.

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Authors and Affiliations

  1. Department of Radiology, Kyoto Renaiss Hospital, 1–38 Suehiro-cho, Fukuchiyama, Kyoto, 620-0054, Japan

    Kiyokazu Kobayashi & Keiji Shimoyama

  2. Department of Internal Medicine, Kyoto Renaiss Hospital, 1–38 Suehiro-cho, Fukuchiyama, Kyoto, 620-0054, Japan

    Keiya Nakamura

  3. Department of Radiology, Shiga University of Medical Science, Seta-Tsukinowa-cho, Otsu, Shiga, 520-2192, Japan

    Kiyoshi Murata

Authors
  1. Kiyokazu Kobayashi
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  2. Keiji Shimoyama
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  4. Kiyoshi Murata
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Correspondence to Kiyokazu Kobayashi.

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Kobayashi, K., Shimoyama, K., Nakamura, K. et al. Percutaneous vertebroplasty immediately relieves pain of osteoporotic vertebral compression fractures and prevents prolonged immobilization of patients. Eur Radiol 15, 360–367 (2005). https://doi.org/10.1007/s00330-004-2549-0

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  • DOI: https://doi.org/10.1007/s00330-004-2549-0

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