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Blinatumomab in relapsed/refractory diffuse large B cell lymphoma

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References

  1. Coiffier B, Lepage E, Briere J, Herbrecht R, Tilly H, Bouabdallah R, Morel P, Van Den Neste E, Salles G, Gaulard P, Reyes F, Lederlin P, Gisselbrecht C (2002) CHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large-B-cell lymphoma. N Engl J Med 346:235–242. doi:10.1056/NEJMoa011795

    Article  CAS  PubMed  Google Scholar 

  2. Tilly H, Vitolo U, Walewski J, Gomes da Silva M, Shpilberg O, André M, Pfreundschuch M, Dreyling M (2015) Diffuse large B-cell lymphoma (DLBCL): ESMO clinical practice guidelines for diagnosis, treatment and follow-up. Ann Oncol 26:v116–v125. doi:10.1093/annonc/mdv304

    Article  PubMed  Google Scholar 

  3. Philip T, Guglielmi C, Hagenbeek A, Somers R, Van Der Lelie H, Bron D, Sonneveld P, Gisselbrechts C, Cahn JY, Harousseau JL, Coiffier B, Biron P, Mandelli F, Chauvin F (1995) Autologous bone marrow transplantation as compared with salvage chemotherapy in relapses of chemotherapy-sensitive non-Hodgkin’s lymphoma. N Engl J Med 333:1540–1545. doi:10.1056/NEJM199512073332305

    Article  CAS  PubMed  Google Scholar 

  4. Gisselbrecht C, Glass B, Mounier N, Singh Gill D, Linch DC, Trneny M, Bosly A, Ketterer N, Shpilberg O, Hagberg H, Ma D, Brière J, Moskowitz CH, Schmitz N (2010) Salvage regimens with autologous transplantation for relapsed large B-cell lymphoma in the rituximab era. J Clin Oncol 28:4184–4190. doi:10.1200/JCO.2010.28.1618

    Article  PubMed  PubMed Central  Google Scholar 

  5. Viardot A, Goebeler ME, Hess G, Neumann S, Pfreundschuh M, Adrian N, Zetti F, Libicher M, Sayehli C, Stieglmaier J, Zhang A, Nagorsen D, Bargou RC (2016) Phase 2 study of the bispecific T-cell engager (BiTE) antibody blinatumomab in relapses/refractory diffuse large B-cell lymphoma. Blood 127:1410–1416. doi:10.1182/blood-2015-06-651380

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Goebeler ME, Knop S, Viardot A, Kufer P, Topp MS, Einsele H, Noppeney R, Hess G, Kallert S, Mackensen A, Rupertus K, Kanz L, Libicher M, Nagorsen D, Zugmaier G, Klinger M, Wolf A, Dorsch B, Quendnau BD, Schmidt M, Scheele J, Baeuerle PA, Leo E, Bargou RC (2016) Bispecific T-cell engager (BiTE) antibody construct Blinatumomab for the treatment of patients with relapsed/refractory non-Hodgkin lymphoma: final results from a phase 1 study. J Clin Oncol 34:1104–1111. doi:10.1200/JCO.2014.59.1586

    Article  CAS  PubMed  Google Scholar 

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Acknowledgments

All authors were part of the team that treated this patient. The term BiTE is a registered trademark of Amgen Inc.

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Authors and Affiliations

  1. Department of Internal Medicine, Leuven University Hospitals, Leuven, Belgium

    Ruben Van Dijck

  2. Department of Hematology, Leuven University Hospitals, Herestraat 49, 3000, Leuven, Belgium

    Ann Janssens, Daan Dierickx, Michel Delforge & Gregor Verhoef

  3. Department of Nuclear Medicine, Leuven University Hospitals, Leuven, Belgium

    Olivier Gheysens

  4. Department of Pathology, Leuven University Hospitals, Leuven, Belgium

    Thomas Tousseyn

Authors
  1. Ruben Van Dijck
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  2. Ann Janssens
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  3. Daan Dierickx
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  4. Michel Delforge
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  5. Olivier Gheysens
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  6. Thomas Tousseyn
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  7. Gregor Verhoef
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Corresponding author

Correspondence to Gregor Verhoef.

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Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.

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Van Dijck, R., Janssens, A., Dierickx, D. et al. Blinatumomab in relapsed/refractory diffuse large B cell lymphoma. Ann Hematol 96, 1759–1762 (2017). https://doi.org/10.1007/s00277-017-3088-5

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  • DOI: https://doi.org/10.1007/s00277-017-3088-5

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