Abstract
Background
Postoperative delirium is associated with adverse outcome. The aim of this study was to find a valid and easy-to-use tool to screen for postoperative delirium on the surgical ward.
Methods
Data were collected from 88 patients who underwent elective surgery. Delirium screening was performed daily until the sixth postoperative day using the Confusion Assessment Method (CAM), the Nursing Delirium Screening Scale (Nu-DESC), and the Delirium Detection Score (DDS), and the DSM-IV criteria as the gold standard.
Results
Seventeen of 88 patients (19%) developed delirium on at least one of the postoperative days according to the gold standard. The DDS scored positive for 40 (45%) patients, the CAM for 15 (17%), and the Nu-DESC for 28 (32%) patients. Sensitivity and specificity were 0.71 and 0.87 for the DDS, 0.75 and 1.00 for the CAM, and 0.98 and 0.92 for the Nu-DESC. The interrater reliability was 0.83 for the Nu-DESC, 0.77 for the DDS, and 1.00 for the CAM.
Conclusions
All scores showed high specificity but differed in their sensitivity. The Nu-DESC proved to be the most sensitive test for screening for a postoperative delirium on the surgical ward followed by the CAM and DDS when compared to the gold standard.
Similar content being viewed by others
References
Armstrong SC, Cozza KL, Watanabe KS (1997) The misdiagnosis of delirium. Psychosomatics 38:433–439
Elie M, Cole MG, Primeau FJ et al (1998) Delirium risk factors in elderly hospitalized patients. J Gen Intern Med 13:204–212
Fick DM, Agostini JV, Inouye SK (2002) Delirium superimposed on dementia: a systematic review. J Am Geriatr Soc 50:1723–1732
Inouye SK (1994) The dilemma of delirium: clinical and research controversies regarding diagnosis and evaluation of delirium in hospitalized elderly medical patients. Am J Med 97:278–288
Francis J (1992) Delirium in older patients. J Am Geriatr Soc 40:829–838
Liptzin B (1999) What criteria should be used for the diagnosis of delirium? Dement Geriatr Cogn Disord 10:364–367
Tucker GJ (1999) The diagnosis of delirium and DSM-IV. Dement Geriatr Cogn Disord 10:359–363
Lipowski ZJ (1980) Delirium updated. Compr Psychiatry 21:190–196
O’Keeffe ST (1999) Clinical subtypes of delirium in the elderly. Dement Geriatr Cogn Disord 10:380–385
Rockwood K, Cosway S, Stolee P et al (1994) Increasing the recognition of delirium in elderly patients. J Am Geriatr Soc 42:252–256
Corsinovi L, Bo M, Ricauda AN et al (2009) Predictors of falls and hospitalization outcomes in elderly patients admitted to an acute geriatric unit. Arch Gerontol Geriatr 49:142–145
Ely EW, Gautam S, Margolin R et al (2001) The impact of delirium in the intensive care unit on hospital length of stay. Intensive Care Med 27:1892–1900
Leslie DL, Zhang Y, Holford TR et al (2005) Premature death associated with delirium at 1-year follow-up. Arch Intern Med 165:1657–1662
O’Keeffe ST, Ni CA (1994) Postoperative delirium in the elderly. Br J Anaesth 73:673–687
Lundstrom M, Edlund A, Karlsson S et al (2005) A multifactorial intervention program reduces the duration of delirium, length of hospitalization, and mortality in delirious patients. J Am Geriatr Soc 53:622–628
Milisen K, Foreman MD, Abraham IL et al (2001) A nurse-led interdisciplinary intervention program for delirium in elderly hip-fracture patients. J Am Geriatr Soc 49:523–532
Naughton BJ, Saltzman S, Ramadan F et al (2005) A multifactorial intervention to reduce prevalence of delirium and shorten hospital length of stay. J Am Geriatr Soc 53:18–23
Yang FM, Inouye SK, Fearing MA et al (2008) Participation in activity and risk for incident delirium. J Am Geriatr Soc 56:1479–1484
Gaudreau JD, Gagnon P, Harel F et al (2005) Fast, systematic, and continuous delirium assessment in hospitalized patients: the nursing delirium screening scale. J Pain Symptom Manage 29:368–375
Inouye SK, van Dyck CH, Alessi CA et al (1990) Clarifying confusion: the confusion assessment method. A new method for detection of delirium. Ann Intern Med 113:941–948
Otter H, Martin J, Basell K et al (2005) Validity and reliability of the DDS for severity of delirium in the ICU. Neurocrit Care 2:150–158
Laurila JV, Pitkala KH, Strandberg TE et al (2004) Impact of different diagnostic criteria on prognosis of delirium: a prospective study. Dement Geriatr Cogn Disord 18:240–244
Monette J, Galbaud du FG, Fung SH et al (2001) Evaluation of the confusion assessment method (CAM) as a screening tool for delirium in the emergency room. Gen Hosp Psychiatry 23:20–25
Laurila JV, Pitkala KH, Strandberg TE et al (2002) Confusion assessment method in the diagnostics of delirium among aged hospital patients: would it serve better in screening than as a diagnostic instrument? Int J Geriatr Psychiatry 17:1112–1119
Radtke FM, Franck M, Schneider M et al (2008) Comparison of three scores to screen for delirium in the recovery room. Br J Anaesth 101:338–343
Lee EW, Dubin N (1994) Estimation and sample size considerations for clustered binary responses. Stat Med 13:1241–1252
Bickel H, Gradinger R, Kochs E et al (2008) High risk of cognitive and functional decline after postoperative delirium. A three-year prospective study. Dement Geriatr Cogn Disord 26:26–31
McAlpine JN, Hodgson EJ, Abramowitz S et al (2008) The incidence and risk factors associated with postoperative delirium in geriatric patients undergoing surgery for suspected gynecologic malignancies. Gynecol Oncol 109:296–302
Minden SL, Carbone LA, Barsky A et al (2005) Predictors and outcomes of delirium. Gen Hosp Psychiatry 27:209–214
Norkiene I, Ringaitiene D, Misiuriene I et al (2007) Incidence and precipitating factors of delirium after coronary artery bypass grafting. Scand Cardiovasc J 41:180–185
Cole M, McCusker J, Dendukuri N et al (2003) The prognostic significance of subsyndromal delirium in elderly medical inpatients. J Am Geriatr Soc 51:754–760
Klugkist M, Sedemund-Adib B, Schmidtke C et al (2008) Confusion assessment method for the intensive care unit (CAM-ICU): diagnosis of postoperative delirium in cardiac surgery. Anaesthesist 57:464–474
Marcantonio E, Ta T, Duthie E et al (2002) Delirium severity and psychomotor types: their relationship with outcomes after hip fracture repair. J Am Geriatr Soc 50:850–857
Leung JM, Leung VW, Leung CM et al (2008) Clinical utility and validation of two instruments (the confusion assessment method algorithm and the chinese version of nursing delirium screening scale) to detect delirium in geriatric inpatients. Gen Hosp Psychiatry 30:171–176
Rolfson DB, McElhaney JE, Jhangri GS et al (1999) Validity of the confusion assessment method in detecting postoperative delirium in the elderly. Int Psychogeriatr 11:431–438
Inouye SK, Charpentier PA (1996) Precipitating factors for delirium in hospitalized elderly persons. Predictive model and interrelationship with baseline vulnerability. JAMA 275:852–857
Redelmeier DA, Thiruchelvam D, Daneman N (2008) Delirium after elective surgery among elderly patients taking statins. CMAJ 179:645–652
Yildizeli B, Ozyurtkan MO, Batirel HF et al (2005) Factors associated with postoperative delirium after thoracic surgery. Ann Thorac Surg 79:1004–1009
Inouye SK (2006) Delirium in older persons. N Engl J Med 354:1157–1165
Acknowledgment
This work was funded by Charité–Universitaetsmedizin Berlin.
Author information
Authors and Affiliations
Corresponding author
Additional information
F. M. Radtke and M. Franck contributed equally to this work.
Rights and permissions
About this article
Cite this article
Radtke, F.M., Franck, M., Schust, S. et al. A Comparison of Three Scores to Screen for Delirium on the Surgical Ward. World J Surg 34, 487–494 (2010). https://doi.org/10.1007/s00268-009-0376-9
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00268-009-0376-9