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Congenital peribronchial myofibroblastic tumor: prenatal imaging clues to differentiate from other fetal chest lesions

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Abstract

We present a prenatal case of congenital peribronchial myofibroblastic tumor referred as a congenital pulmonary airway malformation (CPAM) with hydrops and polyhydramnios at 30 weeks’ gestational age. US and fetal MRI findings did not fit with the referral diagnosis, raising the possibility of intrinsic lung tumor. Fetal hydrops worsened and the baby was successfully delivered by ex utero intrapartum treatment (EXIT) to resection at 31 weeks’ gestational age. To the best of our knowledge, this is a unique case of congenital peribronchial myofibroblastic tumor that underwent comprehensive prenatal evaluation and EXIT procedure with good outcome.

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References

  1. McGinnis M, Jacobs G, el-Naggar A et al (1993) Congenital peribronchial myofibroblastic tumor (so-called ‘congenital leiomyosarcoma’). A distinct neonatal lung lesion associated with nonimmune hydrops fetalis. Mod Pathol 6:487–492

    PubMed  CAS  Google Scholar 

  2. Reiss A, Goldberg Y, Monichor M et al (2005) Congenital pulmonary myofibroblastic tumor—pathology and prenatal sonographic appearance. Prenat Diagn 25:1064–1066

    Article  PubMed  Google Scholar 

  3. Horikoshi T, Kikuchi A, Matsumoto Y et al (2005) Fetal hydrops associated with congenital pulmonary myofibroblastic tumor. J Obstet Gynaecol Res 31:552–555

    Article  PubMed  Google Scholar 

  4. Rypens F, Metens T, Rocourt N et al (2001) Fetal lung volume: estimation at MR imaging—initial results. Radiology 219:236–241

    Article  PubMed  CAS  Google Scholar 

  5. Beydon N, Larroquet M, Coulomb A et al (2013) Comparison between US and MRI in the prenatal assessment of lung malformations. Pediatr Radiol 43:685–696

    Article  PubMed  Google Scholar 

  6. Dishop MK, Kuruvilla S (2008) Primary and metastatic lung tumors in the pediatric population: a review and 25-year experience at a large children’s hospital. Arch Pathol Lab Med 132:1079–1103

    PubMed  Google Scholar 

  7. Dishop MK, McKay EM, Kreiger PA et al (2010) Fetal lung interstitial tumor (FLIT): a proposed newly recognized lung tumor of infancy to be differentiated from cystic pleuropulmonary blastoma and other developmental pulmonary lesions. Am J Surg Pathol 34:1762–1772

    Article  PubMed  Google Scholar 

  8. Huppmann AR, Coffin CM, Hoot AC et al (2011) Congenital peribronchial myofibroblastic tumor: comparison of fetal and postnatal morphology. Pediatr Dev Pathol 14:124–129

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Radiology, MLC 5031, Cincinnati Children’s Hospital Medical Center, 3333 Burnet Ave., Cincinnati, OH, 45229-3026, USA

    Maria A. Calvo-Garcia, Constance Bitters & Beth M. Kline-Fath

  2. Department of Pediatric Surgery and Fetal Care Center of Cincinnati, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA

    Foong-Yen Lim

  3. Department of Pathology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA

    Jerzy Stanek

Authors
  1. Maria A. Calvo-Garcia
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  2. Foong-Yen Lim
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  3. Jerzy Stanek
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  4. Constance Bitters
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  5. Beth M. Kline-Fath
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Corresponding author

Correspondence to Maria A. Calvo-Garcia.

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Calvo-Garcia, M.A., Lim, FY., Stanek, J. et al. Congenital peribronchial myofibroblastic tumor: prenatal imaging clues to differentiate from other fetal chest lesions. Pediatr Radiol 44, 479–483 (2014). https://doi.org/10.1007/s00247-013-2817-8

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  • DOI: https://doi.org/10.1007/s00247-013-2817-8

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