Skip to main content

Advertisement

SpringerLink
Log in

Association Between Sarcopenic Obesity and Pulmonary Function in Korean Elderly: Results from the Korean National Health and Nutrition Examination Survey

  • Original Research
  • Published:
Calcified Tissue International Aims and scope Submit manuscript

Abstract

Although body composition is related to lung function, few studies have reported the effects of sarcopenic obesity on lung function. Thus, the aim of this study was to investigate the associations between lung function and sarcopenia in the presence and in the absence of obesity. We analyzed nationally representative data of 3044 adults aged > 60 years as collated by the ‘Korean National Health and Nutrition Examination Survey 2014–2016. Subjects were classified into four groups: non-sarcopenic non-obese (S−O−), non-sarcopenic obese (S−O+), sarcopenic non-obese (S+O−), and sarcopenic obese (S+O+) according to handgrip strength (GS) and body mass index (BMI). GS was found to be positively associated with forced volume vital capacity (FVC). The S+O+ group had significantly lower FVC values than the S−O− group. Subjects in the S+O+ group were more likely to have restrictive lung disease than those in the S−O− group (odds ratios [ORs] 2.81, 95% confidence interval [CI] 1.72–4.59), and the ORs of restrictive lung disease in S+O+ group were higher than in the S−O+ or S+O− groups. These results were consistent after stratifying by sex and age (61–70 and 71–80). FEV1/FVC ratios (a marker for obstructive lung disease) were not significantly different between S+O+ and S−O− groups. Sarcopenic obesity is associated with a higher risk of restrictive lung disease in Korean elderly.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

Similar content being viewed by others

References

  1. Batsis JA, Villareal DT (2018) Sarcopenic obesity in older adults: aetiology, epidemiology and treatment strategies. Nat Rev Endocrinol 14:513–537

    Article  Google Scholar 

  2. Marty E, Liu Y, Samuel A, Or O, Lane J (2017) A review of sarcopenia: enhancing awareness of an increasingly prevalent disease. Bone 105:276–286

    Article  Google Scholar 

  3. Janssen I (2006) Influence of sarcopenia on the development of physical disability: the cardiovascular health study. J Am Geriatr Soc 54:56–62

    Article  Google Scholar 

  4. Verschueren S, Gielen E, O’’eill TW, Pye SR, Adams JE, Ward KA, Wu FC, Szulc P, Laurent M, Claessens F, Vanderschueren D, Boonen S (2013) Sarcopenia and its relationship with bone mineral density in middle-aged and elderly European men. Osteoporos Int 24:87–98

    Article  CAS  Google Scholar 

  5. Lee J, Hong YP, Shin HJ, Lee W (2016) Associations of sarcopenia and sarcopenic obesity with metabolic syndrome considering both muscle mass and muscle strength. J Prev Med Public Health 49:35–44

    Article  Google Scholar 

  6. Arango-Lopera VE, Arroyo P, Gutierrez-Robledo LM, Perez-Zepeda MU, Cesari M (2013) Mortality as an adverse outcome of sarcopenia. J Nutr Health Aging 17:259–262

    Article  CAS  Google Scholar 

  7. Baumgartner RN, Wayne SJ, Waters DL, Janssen I, Gallagher D, Morley JE (2004) Sarcopenic obesity predicts instrumental activities of daily living disability in the elderly. Obes Res 12:1995–2004

    Article  Google Scholar 

  8. Baek SJ, Nam GE, Han KD, Choi SW, Jung SW, Bok AR, Kim YH, Lee KS, Han BD, Kim DH (2014) Sarcopenia and sarcopenic obesity and their association with dyslipidemia in Korean elderly men: the 2008–2010 Korea National Health and Nutrition Examination Survey. J Endocrinol Invest 37:247–260

    Article  CAS  Google Scholar 

  9. Lee S, Kim TN, Kim SH (2012) Sarcopenic obesity is more closely associated with knee osteoarthritis than is nonsarcopenic obesity: a cross-sectional study. Arthritis Rheum 64:3947–3954

    Article  Google Scholar 

  10. Jeon YK, Shin MJ, Kim MH, Mok JH, Kim SS, Kim BH, Kim SJ, Kim YK, Chang JH, Shin YB, Kim IJ (2015) Low pulmonary function is related with a high risk of sarcopenia in community-dwelling older adults: the Korea National Health and Nutrition Examination Survey (KNHANES) 2008–2011. Osteoporos Int 26:2423–2429

    Article  CAS  Google Scholar 

  11. Park CH, Yi Y, Do JG, Lee YT, Yoon KJ (2018) Relationship between skeletal muscle mass and lung function in Korean adults without clinically apparent lung disease. Medicine (Baltimore) 97:e12281

    Article  Google Scholar 

  12. Lim S, Kwon SY, Yoon JW, Kim SY, Choi SH, Park YJ, Yoon HI, Chang YS, Lee JH, Lee CT, Kim KW, Park KS, Jang HC (2011) Association between body composition and pulmonary function in elderly people: the Korean Longitudinal Study on Health and Aging. Obesity (Silver Spring) 19:631–638

    Article  Google Scholar 

  13. Melo LC, Silva MA, Calles AC (2014) Obesity and lung function: a systematic review. Einstein (Sao Paulo) 12:120–125

    Article  Google Scholar 

  14. Li AM, Chan D, Wong E, Yin J, Nelson EA, Fok TF (2003) The effects of obesity on pulmonary function. Arch Dis Child 88:361–363

    Article  CAS  Google Scholar 

  15. Jones RL, Nzekwu MM (2006) The effects of body mass index on lung volumes. Chest 130:827–833

    Article  Google Scholar 

  16. Moon JH, Kong MH, Kim HJ (2015) Implication of sarcopenia and sarcopenic obesity on lung function in healthy elderly: using Korean National Health and Nutrition Examination Survey. J Korean Med Sci 30:1682–1688

    Article  Google Scholar 

  17. Cruz-Jentoft AJ, Bahat G, Bauer J, Boirie Y, Bruyere O, Cederholm T, Cooper C, Landi F, Rolland Y, Sayer AA, Schneider SM, Sieber CC, Topinkova E, Vandewoude M, Visser M, Zamboni M, Writing Group for the European Working Group on Sarcopenia in Older P, the Extended Group for E (2019) Sarcopenia: revised European consensus on definition and diagnosis. Age Ageing 48:16–31

    Article  Google Scholar 

  18. Kim Y (2014) The Korea National Health and Nutrition Examination Survey (KNHANES): current status and challenges. Epidemiol Health 36:e2014002

    Article  Google Scholar 

  19. Wind AE, Takken T, Helders PJ, Engelbert RH (2010) Is grip strength a predictor for total muscle strength in healthy children, adolescents, and young adults? Eur J Pediatr 169:281–287

    Article  Google Scholar 

  20. Son DH, Yoo JW, Cho MR, Lee YJ (2018) Relationship between handgrip strength and pulmonary function in apparently healthy older women. J Am Geriatr Soc 66:1367–1371

    Article  Google Scholar 

  21. Miller MR, Hankinson J, Brusasco V, Burgos F, Casaburi R, Coates A, Crapo R, Enright P, van der Grinten CP, Gustafsson P, Jensen R, Johnson DC, MacIntyre N, McKay R, Navajas D, Pedersen OF, Pellegrino R, Viegi G, Wanger J, Force AET (2005) Standardisation of spirometry. Eur Respir J 26:319–338

    Article  CAS  Google Scholar 

  22. Choi JK, Paek D, Lee JO (2005) Normal predictive values of spirometry in Korean population. Tuberc Respir Dis 58:230–242

    Article  Google Scholar 

  23. Yoo JI, Choi H, Ha YC (2017) Mean hand grip strength and cut-off value for Sarcopenia in korean adults using Knhanes VI. J Korean Med Sci 32:868–872

    Article  Google Scholar 

  24. Oh SW (2011) Obesity and metabolic syndrome in Korea. Diabetes Metab J 35:561–566

    Article  Google Scholar 

  25. Jeon YK, Shin MJ, Kim CM, Lee BJ, Kim SH, Chae DS, Park JH, So YS, Park H, Lee CH, Kim BC, Chang JH, Shin YB, Kim IJ (2018) Effect of squat exercises on lung function in elderly women with sarcopenia. J Clin Med 7:167

    Article  Google Scholar 

  26. Salome CM, King GG (1985) Berend N (2010) Physiology of obesity and effects on lung function. J Appl Physiol 108:206–211

    Article  Google Scholar 

  27. Aaron SD, Fergusson D, Dent R, Chen Y, Vandemheen KL, Dales RE (2004) Effect of weight reduction on respiratory function and airway reactivity in obese women. Chest 125:2046–2052

    Article  Google Scholar 

  28. van de Griendt EJ, van der Baan-Slootweg OH, van Essen-Zandvliet EE, van der Palen J, Tamminga-Smeulders CL, Benninga MA, van Aalderen WM (2012) Gain in lung function after weight reduction in severely obese children. Arch Dis Child 97:1039–1042

    Article  Google Scholar 

  29. Campos EC, Peixoto-Souza FS, Alves VC, Basso-Vanelli R, Barbalho-Moulim M, Laurino-Neto RM, Costa D (2018) Improvement in lung function and functional capacity in morbidly obese women subjected to bariatric surgery. Clinics (Sao Paulo) 73:e20

    Article  Google Scholar 

  30. Qaseem A, Wilt TJ, Weinberger SE, Hanania NA, Criner G, van der Molen T, Marciniuk DD, Denberg T, Schunemann H, Wedzicha W, MacDonald R, Shekelle P, American College of P, American College of Chest P, American Thoracic S, European Respiratory S (2011) Diagnosis and management of stable chronic obstructive pulmonary disease: a clinical practice guideline update from the American College of Physicians, American College of Chest Physicians, American Thoracic Society, and European Respiratory Society. Ann Intern Med 155:179–191

    Article  Google Scholar 

  31. Limpawattana P, Inthasuwan P, Putraveephong S, Boonsawat W, Theerakulpisut D, Sawanyawisuth K (2018) Sarcopenia in chronic obstructive pulmonary disease: A study of prevalence and associated factors in the Southeast Asian population. Chron Respir Dis 15:250–257

    Article  Google Scholar 

  32. Koo HK, Park JH, Park HK, Jung H, Lee SS (2014) Conflicting role of sarcopenia and obesity in male patients with chronic obstructive pulmonary disease: Korean National Health and Nutrition Examination Survey. PLoS ONE 9:e110448

    Article  Google Scholar 

  33. Zakaria R, Harif N, Al-Rahbi B, Aziz CBA, Ahmad AH (2019) Gender Differences and Obesity Influence on Pulmonary Function Parameters. Oman Med J 34:44–48

    Article  Google Scholar 

  34. LoMauro A, Aliverti A (2018) Sex differences in respiratory function. Breathe (Sheff) 14:131–140

    Google Scholar 

  35. Kweon S, Kim Y, Jang MJ, Kim Y, Kim K, Choi S, Chun C, Khang YH, Oh K (2014) Data resource profile: the Korea National Health and Nutrition Examination Survey (KNHANES). Int J Epidemiol 43:69–77

    Article  Google Scholar 

  36. Lee HE, Myong JP, Kim HR, Rhee CK, Yoon HK, Koo JW (2016) Incidence and prevalence of idiopathic interstitial pneumonia and idiopathic pulmonary fibrosis in Korea. Int J Tuberc Lung Dis 20:978–984

    Article  Google Scholar 

  37. Ko GT, Chan JC, Cockram CS, Woo J (1999) Prediction of hypertension, diabetes, dyslipidaemia or albuminuria using simple anthropometric indexes in Hong Kong Chinese. Int J Obes Relat Metab Disord 23:1136–1142

    Article  CAS  Google Scholar 

Download references

Acknowledgements

This work was supported by the Dongguk University Research Fund of 2017.

Author information

Authors and Affiliations

  1. Division of Endocrinology and Metabolism, Department of Internal Medicine, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, 27, Dongguk-ro, Ilsandong-gu, Goyang-Si, Gyeonggi-Do, Republic of Korea

    Seung Eun Lee, Kyoung-Ah Kim & Han Seok Choi

  2. Department of Statistics, Dongguk University, 30, Pildong-ro 1-gil, Jung-gu, Seoul, Republic of Korea

    Ju-Hyun Park

  3. Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, 27, Dongguk-ro, Ilsandong-gu, Goyang-Si, Gyeonggi-Do, Republic of Korea

    Yun-Seong Kang

Authors
  1. Seung Eun Lee
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Ju-Hyun Park
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Kyoung-Ah Kim
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Yun-Seong Kang
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Han Seok Choi
    View author publications

    You can also search for this author in PubMed Google Scholar

Contributions

Lee S.E. contributed to the study design and prepared the first draft of the paper. Park J.-H. was responsible for the statistical analysis. Kim K.-A. and Kang Y.-S. interpreted data and critically revised the manuscript. Choi H.S. conceptualized study and is guarantor of this paper. All authors approved the final version. Adjusted for age, education, alcohol consumption, smoking, physical activity, dyslipidemia, hypertension, and diabetes.

Corresponding author

Correspondence to Han Seok Choi.

Ethics declarations

Conflict of interest

The authors have no conflicts of interest to declare.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Lee, S.E., Park, JH., Kim, KA. et al. Association Between Sarcopenic Obesity and Pulmonary Function in Korean Elderly: Results from the Korean National Health and Nutrition Examination Survey. Calcif Tissue Int 106, 124–130 (2020). https://doi.org/10.1007/s00223-019-00623-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00223-019-00623-z

Keywords

Search

Navigation