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Degree and Distribution of Mineralization in the Human Mandibular Condyle

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Abstract

The degree of mineralization of bone (DMB) in the mandibular condyle reflects the age and remodeling rate of the bone tissue. Quantification of DMB facilitates a better understanding of possible effects of adaptive remodeling on mineralization of the condyle and its possible consequences for its mechanical quality. We hypothesized differences in the degree and distribution of mineralization between trabecular and cortical bone and between various cortical regions. Microcomputed tomography was used to measure mineralization in 10 human mandibular condyles. Mean DMB was higher in cortical (1,045 mg hydroxyapatite/cm3) than in trabecular bone (857 mg/cm3) and differed significantly between cortical regions (anterior 987 mg/cm3, posterior 1,028 mg/cm3, subchondral 1,120 mg/cm3). The variation of DMB distribution was significantly larger in the anterior cortex than in the posterior and subchondral cortex, indicating a larger amount of heterogeneity of mineralization anteriorly. Within the cortical bone, DMB increased with the distance from the cortical canals to the periphery. Similarly, the DMB of trabecular bone increased with the distance from the surface of the trabeculae to their cores. It was concluded that the rate of remodeling differs between condylar trabecular and cortical bone and between cortical regions and that DMB is not randomly distributed across the bone. The difference in DMB between condylar cortical and trabecular bone suggests a large difference in Young’s modulus.

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Acknowledgment

We are grateful to Irene Aartman for statistical advice, Peter Brugman for technical assistance, and Jan Harm Koolstra and Geerling Langenbach for their comments on the manuscript. This research was supported by the Inter-University Research School of Dentistry through the Academic Centre for Dentistry Amsterdam.

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Authors and Affiliations

  1. Department of Functional Anatomy, Academic Centre for Dentistry Amsterdam, Universiteit van Amsterdam and Vrije Universiteit, Meibergdreef 15, 1105, AZ, Amsterdam, The Netherlands

    G. A. P. Renders, L. Mulder, L. J. van Ruijven & T. M. G. J. van Eijden

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  1. G. A. P. Renders
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  2. L. Mulder
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  3. L. J. van Ruijven
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  4. T. M. G. J. van Eijden
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Correspondence to T. M. G. J. van Eijden.

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Renders, G.A.P., Mulder, L., van Ruijven, L.J. et al. Degree and Distribution of Mineralization in the Human Mandibular Condyle. Calcif Tissue Int 79, 190–196 (2006). https://doi.org/10.1007/s00223-006-0015-5

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  • DOI: https://doi.org/10.1007/s00223-006-0015-5

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