References
Fusco A., Grieco M., Santoro M., Berlingieri M.T., Di Fiore P.P., Pilotti S., Pierotti M.A., Deila Porta G., Vecchio G. A new oncogene in human thyroid papillary carcinomas and their lymph-nodal metastases. Nature 328: 170, 1987.
Grieco M., Santoro M., Berlingieri M.T., Melillo R.M., Donghi R., Bongarzone I., Pierotti M.A., Delia Porta G., Fusco A., Vecchio G. PTC is a novel rearranged form of the ret proto-oncogene and is frequently detected in vivo in human thyroid papillary carcinomas. Cell 60: 557, 1990.
Santoro M., Carlomagno F., Hay I.D., Herrmann M.A., Grieco M., Melillo R., Bongarzone I., Pierotti M.A., Delia Porta G., Berger N., Peix J.L., Paulin C, Fabien N., Vecchio G., Jenkins R.B., Fusco A. RET oncongene activation in human thyroid neoplasms is restricted to the papillary carcinoma subtype. J. Clin. Invest. 89: 1517, 1992.
Pierotti M.A., Santoro M., Jenkins R.B., Sozzi G., Bongarzone I., Grieco M., Monzini N., Miozzo M., Herrmann M.A., Fusco A., Hay I.D., Dello Porta G., Vecchio G. Characterization of a chromosome 10q inversion juxtaposing RET and H4 genes and creating the oncogenic sequence PTC. Proc. Natl. Acad. Sci. USA 89: 1616, 1992.
Bongarzone I., Monzini N., Borrello M.G., Carcano C, Ferraresi Arighi E., Mondellini P., Delia Porta G., Pierotti M.A. Molecular characterization of a thyroid tumor-specific transforming sequence formed by the fusion of ret tyrosine kinase and the regulatory subunit RI of cyclic AMP protein kinase A. Mol. Cell. Biol. 13: 358, 1993.
Santoro M., Dathan N.A., Berlingieri M.T., Bongarzone I., Paulin C, Grieco Pierotti M.A., Vecchio G., Fusco A. Molecular characterization of RET/PTC 3: a novel rearranged version of the RET protooncogene in a human thyroid papillary carcinoma. Oncogene 9: 509, 1994.
Santoro M., Rosati R., Grieco M., Berlingieri M.T., Colucci-DAmato G.L., De Franciscis V., Fusco A. The ret proto-oncogene is consistently expressed in human pheochromocytomas and thyroid medullary carcinomas. Oncogene 5: 1595, 1990.
Mulligan L.M., Kwok J.B.J., Healey C.S., Eisdon M.J., Eng C, Gardner E., Love D.R., Mole S.E., Moore J.K., Papi L., Ponder M.A., Telenius H., Tunnacliffe A., Ponder B.A.J. Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A. Nature 363: 458, 1993.
Donis-Keller H., Dou S., Chi D., Carlson K.M., Toshima K., Lairmore T., Howe J.R., Moley J.F., Goodfellow P., Wells S.A. Mutations in the RET proto-oncogene are associated with MEN2A and FMTC. Human Molecular Genetics 2: 851, 1993.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Fusco, A., Santoro, M., Grieco, M. et al. RET/PTC activation in human thyroid carcinomas. J Endocrinol Invest 18, 127–129 (1995). https://doi.org/10.1007/BF03349720
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF03349720