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Drug-Induced Acute Pancreatitis

A Critical Review

  • Adverse Drag Experience Review
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Summary

Acute pancreatitis has a high morbidity and significant mortality. Among its many causes ethanol is pre-eminent, but many other drugs have also been incriminated. This article begins with a definition of the mechanisms, pathogenesis and clinical features of acute pancreatitis; it then critically reviews the evidence for drugs, excluding ethanol, as being causative. The drugs which have been implicated are considered under 3 headings: definite associations, probable associations and unlikely associations: A brief outline of possible treatment, strategies and prognosis associated with acute pancreatitis concludes the article.

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Authors and Affiliations

  1. Department of Surgery, Clinical Cell Biology and Medicine, M.R.C. Clinical Research Centre and Northwick Park Hospital, London, England

    A. K. Banerjee, K. J. Patel & S. L. Grainger

  2. Gastrointestinal Laboratory, Rayne Institute, St Thomas’s Hospital, London, England

    A. K. Banerjee, K. J. Patel & S. L. Grainger

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  1. A. K. Banerjee
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  2. K. J. Patel
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  3. S. L. Grainger
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Banerjee, A.K., Patel, K.J. & Grainger, S.L. Drug-Induced Acute Pancreatitis. Med Toxicol Adverse Drug Exp 4, 186–198 (1989). https://doi.org/10.1007/BF03259996

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